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The AGT Cytogenetics Laboratory Manual

by Marilyn Arsham Helen J. Lawce Margaret J. Barch

Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics. Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis of G-banded chromosomes, specialized stains that address specific chromosomal structures, and molecular probes, such as fluorescence in situ hybridization (FISH) and chromosome microarray analysis, which employ a variety of methods to highlight a region as small as a single, specific genetic sequence under investigation. The AGT Cytogenetics Laboratory Manual, Fourth Edition offers a comprehensive description of the diagnostic tests offered by the clinical laboratory and explains the science behind them. One of the most valuable assets is its rich compilation of laboratory-tested protocols currently being used in leading laboratories, along with practical advice for nearly every area of interest to cytogeneticists. In addition to covering essential topics that have been the backbone of cytogenetics for over 60 years, such as the basic components of a cell, use of a microscope, human tissue processing for cytogenetic analysis (prenatal, constitutional, and neoplastic), laboratory safety, and the mechanisms behind chromosome rearrangement and aneuploidy, this edition introduces new and expanded chapters by experts in the field. Some of these new topics include a unique collection of chromosome heteromorphisms; clinical examples of genomic imprinting; an example-driven overview of chromosomal microarray; mathematics specifically geared for the cytogeneticist; usage of ISCN’s cytogenetic language to describe chromosome changes; tips for laboratory management; examples of laboratory information systems; a collection of internet and library resources; and a special chapter on animal chromosomes for the research and zoo cytogeneticist. The range of topics is thus broad yet comprehensive, offering the student a resource that teaches the procedures performed in the cytogenetics laboratory environment, and the laboratory professional with a peer-reviewed reference that explores the basis of each of these procedures. This makes it a useful resource for researchers, clinicians, and lab professionals, as well as students in a university or medical school setting.

The AGT Cytogenetics Laboratory Manual

by Marilyn S. Arsham Margaret J. Barch Helen J. Lawce

Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics. Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis of G-banded chromosomes, specialized stains that address specific chromosomal structures, and molecular probes, such as fluorescence in situ hybridization (FISH) and chromosome microarray analysis, which employ a variety of methods to highlight a region as small as a single, specific genetic sequence under investigation. The AGT Cytogenetics Laboratory Manual, Fourth Edition offers a comprehensive description of the diagnostic tests offered by the clinical laboratory and explains the science behind them. One of the most valuable assets is its rich compilation of laboratory-tested protocols currently being used in leading laboratories, along with practical advice for nearly every area of interest to cytogeneticists. In addition to covering essential topics that have been the backbone of cytogenetics for over 60 years, such as the basic components of a cell, use of a microscope, human tissue processing for cytogenetic analysis (prenatal, constitutional, and neoplastic), laboratory safety, and the mechanisms behind chromosome rearrangement and aneuploidy, this edition introduces new and expanded chapters by experts in the field. Some of these new topics include a unique collection of chromosome heteromorphisms; clinical examples of genomic imprinting; an example-driven overview of chromosomal microarray; mathematics specifically geared for the cytogeneticist; usage of ISCN’s cytogenetic language to describe chromosome changes; tips for laboratory management; examples of laboratory information systems; a collection of internet and library resources; and a special chapter on animal chromosomes for the research and zoo cytogeneticist. The range of topics is thus broad yet comprehensive, offering the student a resource that teaches the procedures performed in the cytogenetics laboratory environment, and the laboratory professional with a peer-reviewed reference that explores the basis of each of these procedures. This makes it a useful resource for researchers, clinicians, and lab professionals, as well as students in a university or medical school setting.

The Agulhas Current

by Johann R.E. Lutjeharms

Based on the research findings of 60 years, the author describes the origins of the Agulhas Current, its behaviour, its influence on the adjacent continental shelf, its effect on local weather and its role in linking the Indian and Atlantic Oceans. The text is well-illustrated and includes asides on the history of research on the Current. An exhaustive bibliography gives easy access to present knowledge on this important current system.

The AH Receptor in Biology and Toxicology

by Raimo Pohjanvirta

This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this resource provides a comprehensive reference for readers interested in understanding the full spectrum of AHR, from basic concepts, toxicology analysis, and models to polymorphism and related diseases.

The AH Receptor in Biology and Toxicology

by Raimo Pohjanvirta

This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this resource provides a comprehensive reference for readers interested in understanding the full spectrum of AHR, from basic concepts, toxicology analysis, and models to polymorphism and related diseases.

The Aha! Moment: A Scientist's Take on Creativity

by David Jones

This book is about having ideas and—a much longer haul—making them work. David Jones, best known for his Daedalus column, tells a multitude of stories about creators and their creations, including his own fantastical-seeming contributions to mainstream science such as the unrideable bicycle and chemical gardens in space. His theory of creativity endows each of us with a Random-Ideas Generator, a Censor, and an Observer-Reasoner. Jones applies his theory to a wide range of weird scientific experiments that he has conducted for serious scientific papers, for challenging printed expositions, and for presentations to a TV audience. He even suggests new ones, not yet tried! Creativity is as essential to science as curiosity, physical intuition, and shrewd deduction from well-planned experiments. But, says Jones, ingenuity is very uncertain. Even for the greatest inventors, about 80 percent of ideas fail. Jokiness can help, and so can lots of random data. Jones has plenty of clever advice that will help spark that madly brilliant private thought in the first place—and will encourage you to take it further.Neither dense nor demanding, The Aha! Moment is engrossing, edifying, and scientifically serious; yet it is lightly written and asks lots of silly questions. As Jones shows, it can often pay to take an absurd idea seriously.

The Aha! Moment: A Scientist's Take on Creativity

by David Jones

This book is about having ideas and—a much longer haul—making them work. David Jones, best known for his Daedalus column, tells a multitude of stories about creators and their creations, including his own fantastical-seeming contributions to mainstream science such as the unrideable bicycle and chemical gardens in space. His theory of creativity endows each of us with a Random-Ideas Generator, a Censor, and an Observer-Reasoner. Jones applies his theory to a wide range of weird scientific experiments that he has conducted for serious scientific papers, for challenging printed expositions, and for presentations to a TV audience. He even suggests new ones, not yet tried! Creativity is as essential to science as curiosity, physical intuition, and shrewd deduction from well-planned experiments. But, says Jones, ingenuity is very uncertain. Even for the greatest inventors, about 80 percent of ideas fail. Jokiness can help, and so can lots of random data. Jones has plenty of clever advice that will help spark that madly brilliant private thought in the first place—and will encourage you to take it further.Neither dense nor demanding, The Aha! Moment is engrossing, edifying, and scientifically serious; yet it is lightly written and asks lots of silly questions. As Jones shows, it can often pay to take an absurd idea seriously.

Ahab's Rolling Sea: A Natural History of "Moby-Dick"

by Richard J. King

Although Herman Melville’s Moby-Dick is beloved as one of the most profound and enduring works of American fiction, we rarely consider it a work of nature writing—or even a novel of the sea. Yet Pulitzer Prize–winning author Annie Dillard avers Moby-Dick is the “best book ever written about nature,” and nearly the entirety of the story is set on the waves, with scarcely a whiff of land. In fact, Ishmael’s sea yarn is in conversation with the nature writing of Emerson and Thoreau, and Melville himself did much more than live for a year in a cabin beside a pond. He set sail: to the far remote Pacific Ocean, spending more than three years at sea before writing his masterpiece in 1851. A revelation for Moby-Dick devotees and neophytes alike, Ahab’s Rolling Sea is a chronological journey through the natural history of Melville’s novel. From white whales to whale intelligence, giant squids, barnacles, albatross, and sharks, Richard J. King examines what Melville knew from his own experiences and the sources available to a reader in the mid-1800s, exploring how and why Melville might have twisted what was known to serve his fiction. King then climbs to the crow’s nest, setting Melville in the context of the American perception of the ocean in 1851—at the very start of the Industrial Revolution and just before the publication of On the Origin of Species. King compares Ahab’s and Ishmael’s worldviews to how we see the ocean today: an expanse still immortal and sublime, but also in crisis. And although the concept of stewardship of the sea would have been entirely foreign, if not absurd, to Melville, King argues that Melville’s narrator Ishmael reveals his own tendencies toward what we would now call environmentalism. Featuring a coffer of illustrations and an array of interviews with contemporary scientists, fishers, and whale watch operators, Ahab’s Rolling Sea offers new insight not only into a cherished masterwork and its author but also into our evolving relationship with the briny deep—from whale hunters to climate refugees.

Ahab's Rolling Sea: A Natural History of "Moby-Dick"

by Richard J. King

Although Herman Melville’s Moby-Dick is beloved as one of the most profound and enduring works of American fiction, we rarely consider it a work of nature writing—or even a novel of the sea. Yet Pulitzer Prize–winning author Annie Dillard avers Moby-Dick is the “best book ever written about nature,” and nearly the entirety of the story is set on the waves, with scarcely a whiff of land. In fact, Ishmael’s sea yarn is in conversation with the nature writing of Emerson and Thoreau, and Melville himself did much more than live for a year in a cabin beside a pond. He set sail: to the far remote Pacific Ocean, spending more than three years at sea before writing his masterpiece in 1851. A revelation for Moby-Dick devotees and neophytes alike, Ahab’s Rolling Sea is a chronological journey through the natural history of Melville’s novel. From white whales to whale intelligence, giant squids, barnacles, albatross, and sharks, Richard J. King examines what Melville knew from his own experiences and the sources available to a reader in the mid-1800s, exploring how and why Melville might have twisted what was known to serve his fiction. King then climbs to the crow’s nest, setting Melville in the context of the American perception of the ocean in 1851—at the very start of the Industrial Revolution and just before the publication of On the Origin of Species. King compares Ahab’s and Ishmael’s worldviews to how we see the ocean today: an expanse still immortal and sublime, but also in crisis. And although the concept of stewardship of the sea would have been entirely foreign, if not absurd, to Melville, King argues that Melville’s narrator Ishmael reveals his own tendencies toward what we would now call environmentalism. Featuring a coffer of illustrations and an array of interviews with contemporary scientists, fishers, and whale watch operators, Ahab’s Rolling Sea offers new insight not only into a cherished masterwork and its author but also into our evolving relationship with the briny deep—from whale hunters to climate refugees.

Ahab's Rolling Sea: A Natural History of "Moby-Dick"

by Richard J. King

Although Herman Melville’s Moby-Dick is beloved as one of the most profound and enduring works of American fiction, we rarely consider it a work of nature writing—or even a novel of the sea. Yet Pulitzer Prize–winning author Annie Dillard avers Moby-Dick is the “best book ever written about nature,” and nearly the entirety of the story is set on the waves, with scarcely a whiff of land. In fact, Ishmael’s sea yarn is in conversation with the nature writing of Emerson and Thoreau, and Melville himself did much more than live for a year in a cabin beside a pond. He set sail: to the far remote Pacific Ocean, spending more than three years at sea before writing his masterpiece in 1851. A revelation for Moby-Dick devotees and neophytes alike, Ahab’s Rolling Sea is a chronological journey through the natural history of Melville’s novel. From white whales to whale intelligence, giant squids, barnacles, albatross, and sharks, Richard J. King examines what Melville knew from his own experiences and the sources available to a reader in the mid-1800s, exploring how and why Melville might have twisted what was known to serve his fiction. King then climbs to the crow’s nest, setting Melville in the context of the American perception of the ocean in 1851—at the very start of the Industrial Revolution and just before the publication of On the Origin of Species. King compares Ahab’s and Ishmael’s worldviews to how we see the ocean today: an expanse still immortal and sublime, but also in crisis. And although the concept of stewardship of the sea would have been entirely foreign, if not absurd, to Melville, King argues that Melville’s narrator Ishmael reveals his own tendencies toward what we would now call environmentalism. Featuring a coffer of illustrations and an array of interviews with contemporary scientists, fishers, and whale watch operators, Ahab’s Rolling Sea offers new insight not only into a cherished masterwork and its author but also into our evolving relationship with the briny deep—from whale hunters to climate refugees.

Ahab's Rolling Sea: A Natural History of "Moby-Dick"

by Richard J. King

Although Herman Melville’s Moby-Dick is beloved as one of the most profound and enduring works of American fiction, we rarely consider it a work of nature writing—or even a novel of the sea. Yet Pulitzer Prize–winning author Annie Dillard avers Moby-Dick is the “best book ever written about nature,” and nearly the entirety of the story is set on the waves, with scarcely a whiff of land. In fact, Ishmael’s sea yarn is in conversation with the nature writing of Emerson and Thoreau, and Melville himself did much more than live for a year in a cabin beside a pond. He set sail: to the far remote Pacific Ocean, spending more than three years at sea before writing his masterpiece in 1851. A revelation for Moby-Dick devotees and neophytes alike, Ahab’s Rolling Sea is a chronological journey through the natural history of Melville’s novel. From white whales to whale intelligence, giant squids, barnacles, albatross, and sharks, Richard J. King examines what Melville knew from his own experiences and the sources available to a reader in the mid-1800s, exploring how and why Melville might have twisted what was known to serve his fiction. King then climbs to the crow’s nest, setting Melville in the context of the American perception of the ocean in 1851—at the very start of the Industrial Revolution and just before the publication of On the Origin of Species. King compares Ahab’s and Ishmael’s worldviews to how we see the ocean today: an expanse still immortal and sublime, but also in crisis. And although the concept of stewardship of the sea would have been entirely foreign, if not absurd, to Melville, King argues that Melville’s narrator Ishmael reveals his own tendencies toward what we would now call environmentalism. Featuring a coffer of illustrations and an array of interviews with contemporary scientists, fishers, and whale watch operators, Ahab’s Rolling Sea offers new insight not only into a cherished masterwork and its author but also into our evolving relationship with the briny deep—from whale hunters to climate refugees.

Ahab's Rolling Sea: A Natural History of "Moby-Dick"

by Richard J. King

Although Herman Melville’s Moby-Dick is beloved as one of the most profound and enduring works of American fiction, we rarely consider it a work of nature writing—or even a novel of the sea. Yet Pulitzer Prize–winning author Annie Dillard avers Moby-Dick is the “best book ever written about nature,” and nearly the entirety of the story is set on the waves, with scarcely a whiff of land. In fact, Ishmael’s sea yarn is in conversation with the nature writing of Emerson and Thoreau, and Melville himself did much more than live for a year in a cabin beside a pond. He set sail: to the far remote Pacific Ocean, spending more than three years at sea before writing his masterpiece in 1851. A revelation for Moby-Dick devotees and neophytes alike, Ahab’s Rolling Sea is a chronological journey through the natural history of Melville’s novel. From white whales to whale intelligence, giant squids, barnacles, albatross, and sharks, Richard J. King examines what Melville knew from his own experiences and the sources available to a reader in the mid-1800s, exploring how and why Melville might have twisted what was known to serve his fiction. King then climbs to the crow’s nest, setting Melville in the context of the American perception of the ocean in 1851—at the very start of the Industrial Revolution and just before the publication of On the Origin of Species. King compares Ahab’s and Ishmael’s worldviews to how we see the ocean today: an expanse still immortal and sublime, but also in crisis. And although the concept of stewardship of the sea would have been entirely foreign, if not absurd, to Melville, King argues that Melville’s narrator Ishmael reveals his own tendencies toward what we would now call environmentalism. Featuring a coffer of illustrations and an array of interviews with contemporary scientists, fishers, and whale watch operators, Ahab’s Rolling Sea offers new insight not only into a cherished masterwork and its author but also into our evolving relationship with the briny deep—from whale hunters to climate refugees.

Ahab's Rolling Sea: A Natural History of "Moby-Dick"

by Richard J. King

Although Herman Melville’s Moby-Dick is beloved as one of the most profound and enduring works of American fiction, we rarely consider it a work of nature writing—or even a novel of the sea. Yet Pulitzer Prize–winning author Annie Dillard avers Moby-Dick is the “best book ever written about nature,” and nearly the entirety of the story is set on the waves, with scarcely a whiff of land. In fact, Ishmael’s sea yarn is in conversation with the nature writing of Emerson and Thoreau, and Melville himself did much more than live for a year in a cabin beside a pond. He set sail: to the far remote Pacific Ocean, spending more than three years at sea before writing his masterpiece in 1851. A revelation for Moby-Dick devotees and neophytes alike, Ahab’s Rolling Sea is a chronological journey through the natural history of Melville’s novel. From white whales to whale intelligence, giant squids, barnacles, albatross, and sharks, Richard J. King examines what Melville knew from his own experiences and the sources available to a reader in the mid-1800s, exploring how and why Melville might have twisted what was known to serve his fiction. King then climbs to the crow’s nest, setting Melville in the context of the American perception of the ocean in 1851—at the very start of the Industrial Revolution and just before the publication of On the Origin of Species. King compares Ahab’s and Ishmael’s worldviews to how we see the ocean today: an expanse still immortal and sublime, but also in crisis. And although the concept of stewardship of the sea would have been entirely foreign, if not absurd, to Melville, King argues that Melville’s narrator Ishmael reveals his own tendencies toward what we would now call environmentalism. Featuring a coffer of illustrations and an array of interviews with contemporary scientists, fishers, and whale watch operators, Ahab’s Rolling Sea offers new insight not only into a cherished masterwork and its author but also into our evolving relationship with the briny deep—from whale hunters to climate refugees.

Ahab's Rolling Sea: A Natural History of "Moby-Dick"

by Richard J. King

Although Herman Melville’s Moby-Dick is beloved as one of the most profound and enduring works of American fiction, we rarely consider it a work of nature writing—or even a novel of the sea. Yet Pulitzer Prize–winning author Annie Dillard avers Moby-Dick is the “best book ever written about nature,” and nearly the entirety of the story is set on the waves, with scarcely a whiff of land. In fact, Ishmael’s sea yarn is in conversation with the nature writing of Emerson and Thoreau, and Melville himself did much more than live for a year in a cabin beside a pond. He set sail: to the far remote Pacific Ocean, spending more than three years at sea before writing his masterpiece in 1851. A revelation for Moby-Dick devotees and neophytes alike, Ahab’s Rolling Sea is a chronological journey through the natural history of Melville’s novel. From white whales to whale intelligence, giant squids, barnacles, albatross, and sharks, Richard J. King examines what Melville knew from his own experiences and the sources available to a reader in the mid-1800s, exploring how and why Melville might have twisted what was known to serve his fiction. King then climbs to the crow’s nest, setting Melville in the context of the American perception of the ocean in 1851—at the very start of the Industrial Revolution and just before the publication of On the Origin of Species. King compares Ahab’s and Ishmael’s worldviews to how we see the ocean today: an expanse still immortal and sublime, but also in crisis. And although the concept of stewardship of the sea would have been entirely foreign, if not absurd, to Melville, King argues that Melville’s narrator Ishmael reveals his own tendencies toward what we would now call environmentalism. Featuring a coffer of illustrations and an array of interviews with contemporary scientists, fishers, and whale watch operators, Ahab’s Rolling Sea offers new insight not only into a cherished masterwork and its author but also into our evolving relationship with the briny deep—from whale hunters to climate refugees.

Aharon Katzir Memorial Volume (Biomembranes #7)

by Henryk Eisenberg Ephraim Katchalski-Katzir Lionel A. Manson

It was a warm, sunny morning in Rehovot. The sky was c1ear as it always is in June. As I walked to the Institute that morning, too many cars were passing by, too many people were hurrying onto the Institute's grounds. No one was smiling, acquaintances were recognized by a slight nod of the head. When I turned the corner, a few people already had gathered on the lawn in front of the Jacob Ziskind building. This number was to swell to thousands before the service was over. We were to be joined by the President of Israel, its first Prime Minister, many members of the cabinet, and other great, near-great, working colleagues, and residents of the town. The purpose of all this activity was written on everyone's face, and underlined by the casket that lay in the rotunda of the building. His wife was sitting there, his children, his brother, his students both past and present. One could hear the silence of the participants. I stood inside for a while, overlooking the rotunda. A long line of mourners filed by, offering their sympathies to the family. Suddenly a woman, dressed in black, fell to her knees in front 9f Rina, sobbing. It was the wife of the Japanese Ambassador to Israel. I moved to join the crowd outside. People were standing on the lawn, gingerly trying to avoid stepping on a flower.

AI and Big Data in Cardiology: A Practical Guide

by Nicolas Duchateau Andrew P. King

This book provides a detailed technical overview of the use and applications of artificial intelligence (AI), machine learning and big data in cardiology. Recent technological advancements in these fields mean that there is significant gain to be had in applying these methodologies into day-to-day clinical practice. Chapters feature detailed technical reviews and highlight key current challenges and limitations, along with the available techniques to address them for each topic covered. Sample data sets are also included to provide hands-on tutorials for readers using Python-based Jupyter notebooks, and are based upon real-world examples to ensure the reader can develop their confidence in applying these techniques to solve everyday clinical problems.Artificial Intelligence and Big Data in Cardiology systematically describes and technically reviews the latest applications of AI and big data within cardiology. It is ideal for use by the trainee and practicing cardiologist and informatician seeking an up-to-date resource on the topic with which to aid them in developing a thorough understanding of both basic concepts and recent advances in the field.

AI and Human Thought and Emotion

by Sam Freed

The field of artificial intelligence (AI) has grown dramatically in recent decades from niche expert systems to the current myriad of deep machine learning applications that include personal assistants, natural-language interfaces, and medical, financial, and traffic management systems. This boom in AI engineering masks the fact that all current AI systems are based on two fundamental ideas: mathematics (logic and statistics, from the 19th century), and a grossly simplified understanding of biology (mainly neurons, as understood in 1943). This book explores other fundamental ideas that have the potential to make AI more anthropomorphic. Most books on AI are technical and do not consider the humanities. Most books in the humanities treat technology in a similar manner. AI and Human Thought and Emotion, however is about AI, how academics, researchers, scientists, and practitioners came to think about AI the way they do, and how they can think about it afresh with a humanities-based perspective. The book walks a middle line to share insights between the humanities and technology. It starts with philosophy and the history of ideas and goes all the way to usable algorithms. Central to this work are the concepts of introspection, which is how consciousness is viewed, and consciousness, which is accessible to humans as they reflect on their own experience. The main argument of this book is that AI based on introspection and emotion can produce more human-like AI. To discover the connections among emotion, introspection, and AI, the book travels far from technology into the humanities and then returns with concrete examples of new algorithms. At times philosophical, historical, and technical, this exploration of human emotion and thinking poses questions and provides answers about the future of AI.

AI and Human Thought and Emotion

by Sam Freed

The field of artificial intelligence (AI) has grown dramatically in recent decades from niche expert systems to the current myriad of deep machine learning applications that include personal assistants, natural-language interfaces, and medical, financial, and traffic management systems. This boom in AI engineering masks the fact that all current AI systems are based on two fundamental ideas: mathematics (logic and statistics, from the 19th century), and a grossly simplified understanding of biology (mainly neurons, as understood in 1943). This book explores other fundamental ideas that have the potential to make AI more anthropomorphic. Most books on AI are technical and do not consider the humanities. Most books in the humanities treat technology in a similar manner. AI and Human Thought and Emotion, however is about AI, how academics, researchers, scientists, and practitioners came to think about AI the way they do, and how they can think about it afresh with a humanities-based perspective. The book walks a middle line to share insights between the humanities and technology. It starts with philosophy and the history of ideas and goes all the way to usable algorithms. Central to this work are the concepts of introspection, which is how consciousness is viewed, and consciousness, which is accessible to humans as they reflect on their own experience. The main argument of this book is that AI based on introspection and emotion can produce more human-like AI. To discover the connections among emotion, introspection, and AI, the book travels far from technology into the humanities and then returns with concrete examples of new algorithms. At times philosophical, historical, and technical, this exploration of human emotion and thinking poses questions and provides answers about the future of AI.

AI and Neuro-Degenerative Diseases: Insights and Solutions (Studies in Computational Intelligence #1131)

by Loveleen Gaur Ajith Abraham Reuel Ajith

This book explores the current state of healthcare practice and provides a roadmap for harnessing artificial intelligence (AI) and other modern cognitive technologies for neurogenerative diseases. The main goal of this book is to look at how these techniques can be used to classify patients with neurodegenerative diseases by extracting data from multiple modalities. It demonstrates that the growing development of computer-aided diagnosis systems has a lot of potential to help with the diagnostic process. It offers an analysis of the prospective and perils in implementing such state of the art.Progressive brain disorders with a high prevalence in the general population include Parkinson's disease, Alzheimer's disease and other types of dementia, Huntington's disease, and motor neuron disease. Worldwide, it is estimated that 33 million people have Alzheimer's disease, and 10 million people have Parkinson's disease. The global health economy is significantly impacted by these disorders, which affect both the patient and the caregivers. Various diagnostic techniques are used for differential diagnoses, such as brain imaging, EEG analysis, molecular analysis, and cognitive, psychological, and physical examination. The book aims to develop effective treatments, enhance patient quality of life, and extend life expectancy. It focuses on novel artificial intelligence approaches to clarify the pathogenesis of neurodegenerative disorders and provide early diagnosis.The authors compile recent developments based on machine learning and deep learning techniques to diagnose neurodegenerative diseases using imaging, genetic, and clinical data. The authors support initiatives and methods that aim to improve the application of algorithms in diagnostic practice.

AI and SWARM: Evolutionary Approach to Emergent Intelligence

by Hitoshi Iba

This book provides theoretical and practical knowledge on AI and swarm intelligence. It provides a methodology for EA (evolutionary algorithm)-based approach for complex adaptive systems with the integration of several meta-heuristics, e.g., ACO (Ant Colony Optimization), ABC (Artificial Bee Colony), and PSO (Particle Swarm Optimization), etc. These developments contribute towards better problem-solving methodologies in AI. The book also covers emerging uses of swarm intelligence in applications such as complex adaptive systems, reaction-diffusion computing, and diffusion-limited aggregation, etc. Another emphasis is its real-world applications. We give empirical examples from real-world problems and show that the proposed approaches are successful when addressing tasks from such areas as swarm robotics, silicon traffics, image understanding, Vornoi diagrams, queuing theory, and slime intelligence, etc. Each chapter begins with the background of the problem followed by the current state-of-the-art techniques of the field, and ends with a detailed discussion. In addition, the simulators, based on optimizers such as PSO and ABC complex adaptive system simulation, are described in detail. These simulators, as well as some source codes, are available online on the author’s website for the benefit of readers interested in getting some hands-on experience of the subject. The concepts presented in this book aim to promote and facilitate the effective research in swarm intelligence approaches in both theory and practice. This book would also be of value to other readers because it covers interdisciplinary research topics that encompass problem-solving tasks in AI, complex adaptive systems, and meta-heuristics.

AI and SWARM: Evolutionary Approach to Emergent Intelligence

by Hitoshi Iba

This book provides theoretical and practical knowledge on AI and swarm intelligence. It provides a methodology for EA (evolutionary algorithm)-based approach for complex adaptive systems with the integration of several meta-heuristics, e.g., ACO (Ant Colony Optimization), ABC (Artificial Bee Colony), and PSO (Particle Swarm Optimization), etc. These developments contribute towards better problem-solving methodologies in AI. The book also covers emerging uses of swarm intelligence in applications such as complex adaptive systems, reaction-diffusion computing, and diffusion-limited aggregation, etc. Another emphasis is its real-world applications. We give empirical examples from real-world problems and show that the proposed approaches are successful when addressing tasks from such areas as swarm robotics, silicon traffics, image understanding, Vornoi diagrams, queuing theory, and slime intelligence, etc. Each chapter begins with the background of the problem followed by the current state-of-the-art techniques of the field, and ends with a detailed discussion. In addition, the simulators, based on optimizers such as PSO and ABC complex adaptive system simulation, are described in detail. These simulators, as well as some source codes, are available online on the author’s website for the benefit of readers interested in getting some hands-on experience of the subject. The concepts presented in this book aim to promote and facilitate the effective research in swarm intelligence approaches in both theory and practice. This book would also be of value to other readers because it covers interdisciplinary research topics that encompass problem-solving tasks in AI, complex adaptive systems, and meta-heuristics.

AI and the Future of Education: Teaching in the Age of Artificial Intelligence

by Priten Shah

Clear away the fog surrounding AI in education—and regain your peace of mind Among teachers, there is a cloud of rumors, confusion, and fear surrounding the rise of artificial intelligence. AI and the Future of Education is a timely response to this general state of panic, showing you that AI is a tool to leverage, not a threat to teaching and learning. By understanding what AI is, what it does, and how it can be used to enhance education, you can let go of anxiety and uncertainty, and learn to embrace artificial intelligence. It's true that, along with tremendous opportunities, AI presents some challenges for the field of education. In this book, Priten Shah, a Harvard M.Ed. with a robust background in educational innovation, helps you face these challenges head on, so you can gain the knowledge and skills you need to use AI effectively in your classroom. Thanks to this thorough consideration of ethical considerations and practical approaches, you can develop your own strategy for leveraging AI in administrative tasks, lesson design, professional development, and beyond. Understand what AI and machine learning are, and learn about new developments like ChatGPT Discover strategies for engaging students more fully using AI Automate administrative tasks, grading and feedback, and assessments Use AI in innovative ways to promote higher-order thinking skills Examine ethical considerations of AI, including the achievement gap, privacy concerns, and bias For K-12 educators, as well as leaders and policymakers who want to understand the role of technology in education, AI and the Future of Education is a valuable resource that can change AI from an unknown entity to an indispensable tool.

AI and the Future of Education: Teaching in the Age of Artificial Intelligence

by Priten Shah

Clear away the fog surrounding AI in education—and regain your peace of mind Among teachers, there is a cloud of rumors, confusion, and fear surrounding the rise of artificial intelligence. AI and the Future of Education is a timely response to this general state of panic, showing you that AI is a tool to leverage, not a threat to teaching and learning. By understanding what AI is, what it does, and how it can be used to enhance education, you can let go of anxiety and uncertainty, and learn to embrace artificial intelligence. It's true that, along with tremendous opportunities, AI presents some challenges for the field of education. In this book, Priten Shah, a Harvard M.Ed. with a robust background in educational innovation, helps you face these challenges head on, so you can gain the knowledge and skills you need to use AI effectively in your classroom. Thanks to this thorough consideration of ethical considerations and practical approaches, you can develop your own strategy for leveraging AI in administrative tasks, lesson design, professional development, and beyond. Understand what AI and machine learning are, and learn about new developments like ChatGPT Discover strategies for engaging students more fully using AI Automate administrative tasks, grading and feedback, and assessments Use AI in innovative ways to promote higher-order thinking skills Examine ethical considerations of AI, including the achievement gap, privacy concerns, and bias For K-12 educators, as well as leaders and policymakers who want to understand the role of technology in education, AI and the Future of Education is a valuable resource that can change AI from an unknown entity to an indispensable tool.

The AI Does Not Hate You: Superintelligence, Rationality and the Race to Save the World

by Tom Chivers

'The AI does not hate you, nor does it love you, but you are made of atoms which it can use for something else'This is a book about AI and AI risk. But it's also more importantly about a community of people who are trying to think rationally about intelligence, and the places that these thoughts are taking them, and what insight they can and can't give us about the future of the human race over the next few years. It explains why these people are worried, why they might be right, and why they might be wrong. It is a book about the cutting edge of our thinking on intelligence and rationality right now by the people who stay up all night worrying about it.Along the way, we discover why we probably don't need to worry about a future AI resurrecting a perfect copy of our minds and torturing us for not inventing it sooner, but we perhaps should be concerned about paperclips destroying life as we know it; how Mickey Mouse can teach us an important lesson about how to program AI; and how a more rational approach to life could be what saves us all.

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