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Ethical and Legal Issues in Neurology (ISSN #Volume 118)

Advances in our understanding of the brain and rapid advances in the medical practice of neurology are creating questions and concerns from an ethical and legal perspective. Ethical and Legal Issues in Neurology provides a detailed review of various general aspects of neuroethics, and contains chapters dealing with a vast array of specific issues such as the role of religion, the ethics of invasive neuroscience research, and the impact of potential misconduct in neurologic practice. The book focuses particular attention on problems related to palliative care, euthanasia, dementia, and neurogenetic disorders, and concludes with examinations of consciousness, personal identity, and the definition of death. This volume focuses on practices not only in North America but also in Europe and the developing world. It is a useful resource for all neuroscience and neurology professionals, researchers, students, scholars, practicing clinical neurologists, mental health professionals, and psychiatrists. A comprehensive introduction and reference on neuroethics Includes coverage of how best to understand the ethics and legal aspects of dementia, palliative care, euthanasia and neurogenetic disorders Brings clarity to issues regarding ethics and legal responsibilities in the age of rapidly evolving brain science and related clinical practice

Big Data in Healthcare: Extracting Knowledge from Point-of-Care Machines (SpringerBriefs in Pharmaceutical Science & Drug Development)

This book reviews a number of issues including: Why data generated from POC machines are considered as Big Data. What are the challenges in storing, managing, extracting knowledge from data from POC devices? Why is it inefficient to use traditional data analysis with big data? What are the solutions for the mentioned issues and challenges? What type of analytics skills are required in health care? What big data technologies and tools can be used efficiently with data generated from POC devices? This book shows how it is feasible to store vast numbers of anonymous data and ask highly specific questions that can be performed in real-time to give precise and meaningful evidence to guide public health policy.

Challenges in Mechanics of Time Dependent Materials, Mechanics of Biological Systems and Materials & Micro-and Nanomechanics, Volume 2: Proceedings of the 2021 Annual Conference & Exposition on Experimental and Applied Mechanics (Conference Proceedings of the Society for Experimental Mechanics Series)

Challenges in Mechanics of Time-Dependent Materials, Mechanics of Biological Systems and Materials, and Micro-and Nanomechanics, Volume 2 of the Proceedings of the 2021 SEM Annual Conference & Exposition on Experimental and Applied Mechanics, the second volume of four from the Conference, brings together contributions to this important area of research and engineering. The collection presents early findings and case studies on fundamental and applied aspects of Experimental Mechanics, including papers in the following general technical research areas: Characterization Across Length Scales Extreme Conditions & Environmental Effects Damage, Fatigue and Fracture Structure, Function and Performance Rate Effects in Elastomers Viscoelasticity & Viscoplasticity Research in Progress Extreme Nanomechanics In-Situ Nanomechanics Expanding Boundaries in Metrology Micro and Nanoscale Deformation MEMS for Actuation, Sensing and Characterization 1D & 2D Materials Cardiac Mechanics Cell Mechanics Biofilms and Microbe Mechanics Traumatic Brain Injury Orthopedic Biomechanics Ligaments and Soft Materials

Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology (pdf)

Radiology of the Lower Urinary Tract (Medical Radiology)

Significant recent advances in the imaging of the lower urinary tract are comprehensively presented in this handbook. It offers information on both imaging examinations and interventional techniques with all the modern modalities, including MRI and ultrasound. The contributors are all experts in clinical urology; their varying and at times conflicting opinions track the fast-moving pace in the field and demonstrate the complexity of the subject. The approach is disease-oriented, though grouped by anatomic region. Each chapter covers etiology, physiology, pathology, epidemiology, clinical presentations and especially diagnostic imaging, but also the appropriate interventional radiologic techniques for both diagnosis and treatment.

Stem Cell Technologies in Neuroscience (Neuromethods #126)

This volume provides comprehensive knowledge on the fundamental techniques and detailed laboratory protocols used in stem cell research and their potential application in the field of neuroscience. The chapters in this book cover detailed descriptions of techniques for isolation, maintenance, differentiation, and characterization of neural stem cells, and the development of in vitro stem cell-based neurological disease model. There are detailed methods on leading techniques for stem cell genetic engineering and intra-organ transplantation for research and therapeutic purposes, in vivo imaging of donor stem cells, and essential requirements for setting up a new stem cell laboratory. Neuromethods series offers chapters with key advice and procedure specifics to empower the readers to successfully achieve their own scientific and experimental goals. Cutting-edge and pragmatic, Stem Cell Technologies in Neuroscience is a valuable resource for academic and translational researchers, industry scientists, biology teachers, and life science graduate students to grasp the vital pulse of the rapidly growing field of stem cell research.

Handbook of Endovascular Interventions

Handbook of Endovascular Interventions presents a step-wise approach to the techniques of peripheral vascular interventions. Covering interventions in all major organ systems, this concise and comprehensive resource provides the rationale on why these approaches have been adopted by most practicing vascular interventionalists. This volume also presents key information on intervention techniques and pitfalls, complications and their management, surgical management options, as well as landmark papers on the topic. Unique to this book is the inclusion of sections building an endovascular suite, and coding as well as international training paradigms across the globe.Authored by international experts from around the globe, Handbook of Endovascular Interventions is a true how-to book for the busy interventionalist.

Cancer Neuroscience

This volume is the first on the market to address and discuss the emerging field of cancer neuroscience. Edited by pioneers in the field with contributions from top researchers, the volume serves as a comprehensive overview of the role of nerves in tumorigenesis and cancer progression. Chapters will address how the innervation of tumors can serve as both prognostic and predictive biomarkers as well as actionable therapeutic targets. Authors will describe current research efforts, and future directions for study and translation to the clinic. It is becoming increasingly apparent that certain treatments will need to consider interactions between the nervous system and cancer, and the novel concepts presented in the book address related accumulating evidence regarding therapeutic strategies. This unique volume will be useful for cancer researchers, neuroscientists, cancer biologists, oncologists, and others looking to gain a greater understanding of this emerging field.

Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye

Undoubtedly, Drosophila melanogaster, fruit fly, has proved to be one of the most popular invertebrate model organisms, and the work horse for modern day biologists. Drosophila, a highly versatile model with a genetic legacy of more than a century, provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human diseases. One of the most important questions in biology focuses on how does a multi-cellular organism develop from a single-celled embryo. The discovery of the genes responsible for pattern formation has helped refine this question, and led to other questions, such as the role of various genetics and cell biological pathways in regulating the crucial process of pattern formation and growth during organogenesis. Drosophila eye model has been extensively used to study molecular genetic mechanisms involved in patterning and growth. Since the genetic machinery involved in the Drosophila eye is similar to humans, it has been used to model human diseases and homology to eyes in other taxa. This book will discuss molecular genetic mechanisms of pattern formation, mutations in axial patterning, Genetic regulation of growth in Drosophila eye, and more. There have been no titles in the past ten years covering this topic, thus an update is urgently needed.​

La voce: Uno strumento dei professionisti che promuovono la salute (Metodologie Riabilitative in Logopedia #21)

L'opera offre una panoramica multidisciplinare sulla voce. Racchiude contributi che discipline diverse hanno dato allo studio della voce: strumento essenziale di ogni relazione e di quella d'aituo in particolare.

Water Soluble Polymers: Solution Properties and Applications

This volume contains a series of papers originally presented at the symposium on Water Soluble Polymers: Solution Properties and Applications, sponsored by the Division of Colloids and Surface Chemistry of the American Chemical Society. The symposium took place in Las Vegas City, Nevada on 9 to 11th September, 1997 at the 214th American Chemical Society National Meeting. Recognized experts in their - spective fields were invited to speak. There was a strong attendance from academia, g- ernment, and industrial research centers. The purpose of the symposium was to present and discuss recent developments in the solution properties of water soluble polymers and their applications in aqueous systems. Water soluble polymers find applications in a number of fields of which the following may be worth mentioning: cosmetics, detergent, oral care, industrial water treatment, g- thermal, wastewater treatment, water purification and reuse, pulp and paper production, sugar refining, and many more. Moreover, water soluble polymers play vital role in the oil industry, especially in enhanced oil recovery. Water soluble polymers are also used in ag- culture and controlled release pharmaceutical applications. Therefore, a fundamental kno- edge of solution properties of these polymers is essential for most industrial scientists. An understanding of the basic phenomena involved in the application of these polymers, such as adsorption and interaction with different substrates (i. e. , tooth enamel, hair, reverse - mosis membrane, heat exchanger surfaces, etc. ) is of vital importance in developing high performance formulations for achieving optimum efficiency of the system.

Reizen en ziekte

Steeds meer mensen maken verre reizen. De enorme toename van het internationaal reizen confronteert de huisarts met een groeiende vraag naar advies over vaccinatie en chemoprofylaxe bij het vertrek, en met de diagnostiek van een mogelijk exotische aandoening bij terugkeer. In Reizen en ziekte wordt uitvoerig op deze ontwikkeling ingespeeld. Reizen en ziekte is uit vijf delen opgebouwd. In deel 1 komen algemene onderwerpen aan bod waaronder reizigersconsult en keuring. Deel 2 geeft een overzicht van onderwerpen die van belang zijn voor de vertrekkende reiziger. Op reis gaan met specifieke gezondheidsproblemen of gezondheidsrisico's komt in het derde deel aan bod. Het vierde deel behandelt klachten van de thuiskomende reiziger, zoals diarree, zweten, worminfecties, en deel vijf behandelt de medische problemen bij migranten en adoptiekinderen.

Lymphocyte Stimulation: Differential Sensitivity to Radiation Biochemical and Immunological Processes

This book is a collection of some of the papers presented at the EMBO Lecture Course on "Lymphocyte stimulation: differential sensitivity to radiation; biochemical and immunological properties." The Course was organized with the aim of fostering interactions between photoradiobiologists and immunologists interested in the problem of DNA damage and repair studied at the lymphocyte level. The papers presented in this book are mainly centered on the problem of radiation sensitivity of lymphocytes in relation to DNA repair phenomena. The radiation biology of human lymphocytes is dominated by two phenomena: (a) high radiosensitivity of lymphocytes which die in interphase (b) PHA-induced relative radioresistance of those cells which, after stimulation, escape the interphase death and eventually die in mitosis. These phenomena constitute a good system to study some of the factors which control the response of human cells to irradiation. In addition it is possible to correlate the development of the relative radioresistance in PHA-stimulated lymphocytes with the biochemical changes connected with the transformation processes. The papers presented in this book constitute a real contribution to the scientific knowledge in this field of research and suggest that lymphocytes could be a very interesting test material useful for measuring the DNA repair capability of human cells to furnish an indication of individual radiosensitivity in man.

The Use of Human Cells for the Evaluation of Risk from Physical and Chemical Agents

In this volume are collected 30 papers, 9 round table discus­ sions and 11 communications presented at the ASI Course on "The use of human cells for the evaluation of risk from physical and chemical agents", sponsored by NATO and organized by ENEA. The aim of the Course was to present different scientific ap­ proaches and technical advices in order to get dose-effect relation­ ships which are the basis for risk evaluation. The scientific back­ ground which is behind this approach was extensively discussed. Emphasis has been given to the use of human cells or human data in order to attempt to have a correct and realistic evaluation of the damage in humans. There are many criticisms on the use of animal data for human risk evaluation because of differences between species and between strains within the same species: differences in metabolism, activa­ tion processes and DNA repair ability makes uncertain the extrapola­ tion of animal data to humans. Also data obtained using specific strains or highly inbred strains in order to reduce the variance are not applicable due to the heterogeneity of the human population connected with individual responses. In this respect only the use of human cells enable us to detect the individual variability and to identify sensitive subpopu­ lations that would be at greater risk. My appreciation to Pieranita and Alberto Castellani for the as­ sistance during the meeting and to Giuseppe Biondi for his help in some of the editorial work.

Ion-Selective Microelectrodes: Principles, Design and Application (Advances In Experimental Medicine And Biology Ser. #50)

Fortschritte in der Pankreasfunktionsdiagnostik: Beitrag zum Problem der Diagnose von subakut-chronischen Pankreasaffektionen unter spezieller Berücksichtigung der Stuhlenzymmethode und des Pankreozymin-Secretintests (Experimentelle Medizin, Pathologie und Klinik #22)

Hydrocephalus: What do we know? And what do we still not know?

This book provides the reader with a well-structured, comprehensive approach to hydrocephalus and related syndromes. It also addresses the ethical dilemmas of managing hydrocephalus, of which many neurosurgeons are unaware, and presents cutting-edge research genetic and pathophysiology research on hydrocephalus. The book presents a new classification for the Dandy Walker syndrome, based on a new understanding of different hydrocephalic problems. Further, it puts forward a wholly new theory on the pathophysiology and development of multiloculated hydrocephalus. This book helps the reader to devise a long-term strategic plan to treat patients, based on research of favorable long-term outcomes of hydrocephalus. It uniquely provides evidence-based approaches to managing hydrocephalus, presenting the experience and thoughts of renowned and highly experienced neurosurgeons from the USA, Canada, Japan, Europe and the Middle East.

Learning and Career Development in Neurosurgery: Values-Based Medical Education

The neurosurgical, surgical and medical training and practice models have to keep up with the technological revolution in the 21st Century as our lives changed on a swift base. Making bioethics and metacognition a cornerstone in medical education and practice will flourish our humane societies. Metacognition is thinking about one’s thinking, to plan, monitor and assess one’s understanding and performance. By adherence to medical ethics and Values-Based Medicine (VsBM) as guiding principles, we can develop benevolent medical practice. To enhance knowledge application, skills, and character qualities in realms beyond the immediate context in which they were learned. In this book, we developed a framework on how to evolve medical education and training by utilizing hi-tech. We divided the book into five principal components; Current and traditional root analysis of the learning process, Ethics and metacognition of education, learning and career development, Obstacles, difficulties and setbacks in learning and career development process, Learning in the digital era, and Mentorship. The author believes we are entering a new era of information technology, which will have a significant impact on the education, sciences, strategies and philosophy. Therefore, in preparation for this colossal transformation, the author brings together the best brains in the neurosurgical field from around the globe. Twenty distinguished Professors of Neurosurgery and educators from Canada, the USA, Colombia, the UK, Italy, the Netherland, India, Japan, China, Rwanda, Egypt and Saudi Arabia gathered their experiences and thoughts in this book to shade light on an evolving world that will be the norm in near future.

Neurosurgical Ethics in Practice: Value-based Medicine

Good neurosurgical practice is based not only on evidence, skills, and modern equipment, but also on good values. This book is the first to discuss specifically the ethical issues that arise during the daily practice of neurosurgery. It is divided into three parts addressing patients’ rights, ethical issues relating to the working environment, and wider societal aspects such as dealings of neurosurgeons with the legal system, the media, and companies. The authors are well-established neurosurgeons who present the ethical problems that they have encountered during their careers and explain what they have learned in confronting these problems. In all, more than 50 neurosurgical cases drawn from real life are reported and discussed from an ethical point of view. This book will be especially informative for young neurosurgeons and will provide all who work in this very special field with a road map on how to avoid violations of medical ethics in neurosurgical practice.

Advances in Disease Vector Research (Advances in Disease Vector Research #10)

Volume 10 of Advances in Disease Vector Research consists of seven chapters on vectors that affect human or animal health and six chapters on plant pathogens and their vectors. In Chapter 1, Yasuo Chinzei and DeMar Taylor discuss hormonal regulation of vitellogenesis in ticks. Many blood sucking insects and ticks transmit pathogens by engorgement, which induces vitellogenesis and oviposition in adult animals. To investigate the pathogen transmission mechanism in vector animals, information on the host physiological and endocrinological conditions after engorgement is useful and important because pathogen development or proliferation occurs in the vector hosts at the same time as the host reproduction. Chinzei and Taylor have shown that in ticks, juvenile hormone (JH) is not involved in the endocrinological processes inducing vitellogenin biosynthesis. Synganglion (tick brain) factor(s) (vitellogenesis inducing factor, VIF) is more important to initiate vitellogenesis after engorgement, and ecdysteroids are also related to induction of vitellogenin synthesis. In their chapter, based mainly on their own experimental data, the authors discuss the characterization of main yolk protein, vitellogenin (Vg) , biosynthesis and processing in the fat body, and hormonal regulation of Vg synthesis in tick systems, including ixodid and argasid ticks.

An Introduction to Mathematics of Emerging Biomedical Imaging (Mathématiques et Applications #62)

Biomedical imaging is a fascinating research area to applied mathematicians. Challenging imaging problems arise and they often trigger the investigation of fundamental problems in various branches of mathematics. This is the first book to highlight the most recent mathematical developments in emerging biomedical imaging techniques. The main focus is on emerging multi-physics and multi-scales imaging approaches. For such promising techniques, it provides the basic mathematical concepts and tools for image reconstruction. Further improvements in these exciting imaging techniques require continued research in the mathematical sciences, a field that has contributed greatly to biomedical imaging and will continue to do so. The volume is suitable for a graduate-level course in applied mathematics and helps prepare the reader for a deeper understanding of research areas in biomedical imaging.

Mathematical Modeling in Biomedical Imaging I: Electrical and Ultrasound Tomographies, Anomaly Detection, and Brain Imaging (Lecture Notes in Mathematics #1983)

Mathematical Modeling in Biomedical Imaging II: Optical, Ultrasound, and Opto-Acoustic Tomographies (Lecture Notes in Mathematics #2035)

This volume reports on recent mathematical and computational advances in optical, ultrasound, and opto-acoustic tomographies. It outlines the state-of-the-art and future directions in these fields and provides readers with the most recently developed mathematical and computational tools. It is particularly suitable for researchers and graduate students in applied mathematics and biomedical engineering.

Polarization and Moment Tensors: With Applications to Inverse Problems and Effective Medium Theory (Applied Mathematical Sciences #162)

This book presents important recent developments in mathematical and computational methods used in impedance imaging and the theory of composite materials. By augmenting the theory with interesting practical examples and numerical illustrations, the exposition brings simplicity to the advanced material. An introductory chapter covers the necessary basics. An extensive bibliography and open problems at the end of each chapter enhance the text.

The Thermal Human Body: A Practical Guide to Thermal Imaging

This book is a guide for the constantly growing community of the users of medical thermal imaging. It describes where and how an infrared equipment can be used in a strictly standardised way and how one can ultimately comprehensively report the findings. Due to their insight into the complex mechanisms behind the distribution of surface temperature, future users of medical thermal imaging should be able to provide careful, and cautious, interpretations of infrared thermograms, thus avoiding the pitfalls of the past. The authors are well-known pioneers of the technique of infrared imaging in medicine who have combined strict standard-based evaluation of medical thermal images with their expertise in clinical medicine and related fields of health management.