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Advances in Transplant Dermatology: Clinical and Practical Implications

by Fiona Zwald Marc D. Brown

This book provides an informative update on scientific advances relating to transplant dermatology that may be applicable to clinical practice. Commentary is provided on the emerging role of viruses in transplant dermatology, the management of skin disease secondary to transplant medication, sunscreen use in transplant recipients, the role of revision of immunosuppression, and advances in photodynamic therapy. The latest staging and management criteria for high-risk squamous cell carcinoma and the implications for clinical practice are then analyzed. Finally, the management of other cutaneous malignancies is discussed, covering malignant melanoma, Merkel cell carcinoma, and rarer tumors that also behave aggressively and require special consideration in solid organ transplant patients. Each particular advance is addressed in an individual chapter by leaders in the field. The book both expands current knowledge and complements previous textbooks on the subject.

Psychosoziale Aspekte der Adipositas-Chirurgie

by Martina De Zwaan Stephan Herpertz Stephan Zipfel

Das Buch soll einen ersten Überblick über die psychotherapeutische Begleitung von Patienten vor und nach bariatrischen chirurgischen Eingriffen geben. Es richtet sich an die therapeutischen Teams, die mit Adipositaspatienten vor und nach der Operation arbeiten, soll aber auch Chirurgen für das Thema sensibilisieren. Durch die zunehmende Zahl an entsprechenden Operationen steigt die Notwendigkeit, diese Patienten während des gesamten Prozesses zu begleiten.

Psychosoziale Aspekte der Adipositas-Chirurgie

by Martina De Zwaan Stephan Herpertz Stephan Zipfel

Das Buch soll einen ersten Überblick über die psychotherapeutische Begleitung von Patienten vor und nach bariatrischen chirurgischen Eingriffen geben. Es richtet sich an die therapeutischen Teams, die mit Adipositaspatienten vor und nach der Operation arbeiten, soll aber auch Chirurgen für das Thema sensibilisieren. Durch die zunehmende Zahl an entsprechenden Operationen steigt die Notwendigkeit, diese Patienten während des gesamten Prozesses zu begleiten.

Health, Technologies, and Politics in Post-Soviet Settings: Navigating Uncertainties

by Olga Zvonareva Evgeniya Popova Klasien Horstman

This book uses a variety of empirical cases on topics including drug development, egg donation, and governance of healthcare facilities, to investigate how actors navigate the uncertainties that permeate the interfaces of health, technologies, and politics in post-Soviet settings and what the implications of their chosen navigation routes are. Contemporary societies are imbued with uncertainties, but the authors focus on settings where uncertainties multiply, making decisions, practises, and relations in everyday life precarious. Two worlds are brought into dialogue throughout the chapters of this book with the aim of facilitating mutual learning from one another - the world of science and technology studies (STS) and the high-income liberal democracies of the West, on one hand, and studies of post-socialism on the other. In so doing, this book encourages critical learning on ensuring the resilience of individual and societal health in situations of profound uncertainties. This timely collection will be of great interest to scholars, practitioners and policy makes in the fields of sociology, biomedicine, political science and public and global health.

Health, Technologies, and Politics in Post-Soviet Settings: Navigating Uncertainties

by Olga Zvonareva Evgeniya Popova Klasien Horstman

This book uses a variety of empirical cases on topics including drug development, egg donation, and governance of healthcare facilities, to investigate how actors navigate the uncertainties that permeate the interfaces of health, technologies, and politics in post-Soviet settings and what the implications of their chosen navigation routes are. Contemporary societies are imbued with uncertainties, but the authors focus on settings where uncertainties multiply, making decisions, practises, and relations in everyday life precarious. Two worlds are brought into dialogue throughout the chapters of this book with the aim of facilitating mutual learning from one another - the world of science and technology studies (STS) and the high-income liberal democracies of the West, on one hand, and studies of post-socialism on the other. In so doing, this book encourages critical learning on ensuring the resilience of individual and societal health in situations of profound uncertainties. This timely collection will be of great interest to scholars, practitioners and policy makes in the fields of sociology, biomedicine, political science and public and global health.

Laron Syndrome - From Man to Mouse: Lessons from Clinical and Experimental Experience

by Zvi Laron and J. Kopchick

Laron syndrome (LS), or primary growth hormone (GH) insensitivity, was first described in 1966. Since then, many patients worldwide have been diagnosed with LS, which involves defects in the GH receptor that cause combined congenital deficiency of GH and IGF-I activities. In this comprehensive book the authors draw upon 50 years of multidisciplinary clinical and investigative follow-up of the large Israeli cohort of LS patients. The genetic basis of the syndrome is fully considered, and all aspects of the pathophysiology of IGF-I deficiency are described. Data derived from the recently generated mouse model of LS are reviewed and compared with the human LS experience. Valuable advice is provided on treatment, and treatment effects, such as metabolic effects, adipose tissue alterations, and impact on aging, are fully explored. Together, this book condenses, consolidates, compares, and contrasts data derived from the human and mouse LS experiences and provides a unique resource for clinical and basic scientists to evaluate and compare IGF-I and GH actions.

De dokter en de dood: Optimale zorg in de laatste levensfase

by Lia Van Zuylen Agnes van der Heide Suzanne van de Vathorst Erik Geijteman

Iedereen kent het ongenuanceerde verhaal: dokters zijn opgeleid en gemotiveerd om mensen beter te maken. Maar betekent dat dan automatisch ook dat zulke professionals hun focus verliezen bij patiënten met een infauste prognose?Dokters kunnen zich juist ook in de laatste levensfase buitengewoon verdienstelijk maken.Een complicatie daarbij is wel dat de geneeskunde-opleiding tot op de huidige dag tekort schiet in het overdragen van kennis over (be)handelen zonder curatieve intentie. Mogelijk dat prioriteiten in een overvolle doktersdag daarom wel eens in het voordeel uitvallen van patiënten met een redelijke prognose.Dit boek biedt een praktisch houvast voor artsen en andere zorgprofessionals om optimale omstandigheden te creëren voor patiënten in tijdnood.47 Vakgenoten bewijzen in dit boek dat optimale zorg haalbaar is in de hectische praktijk van alledag.Elk hoofdstuk start met een herkenbare casus. Dan volgt een breder getrokken beschouwing over de geschetste problematiek. Een paragraaf met praktische conclusies completeert het geheel steeds.Aldus komen - soms hoofdbrekende - thema's aan bod:Wat is 'op tijd' vertellen?Hoe gaat een arts om met een terminale patiënt die hoop houdt?Kunnen alle betrokken behandelaars alle relevante gegevens kennen?Is palliatieve sedatie in sommige gevallen geen sluitroute voor euthanasie?waar ligt de grens tussen goed behandelen en te lang doorbehandelen?Maar ook het contact met de familie komt aan de orde. Evenals de wenselijke zorg om de zorgverlener zelf, die immers per definitie vaak moet omgaan met het lijden van patiënten en hun omgeving.“Er is volop discussie gaande over de vraag of mensen die ‘klaar’ zijn met leven geholpen zouden kunnen worden binnen de euthanasiewet. De uitkomst van die discussie kan de grenzen verschuiven, mede afhankelijk van wat de beroepsgroep van artsen tot haar taak en domein rekent.”

Analyzing Ecological Data (Statistics for Biology and Health)

by Alain Zuur Elena N. Ieno Graham M. Smith

This book provides a practical introduction to analyzing ecological data using real data sets. The first part gives a largely non-mathematical introduction to data exploration, univariate methods (including GAM and mixed modeling techniques), multivariate analysis, time series analysis, and spatial statistics. The second part provides 17 case studies. The case studies include topics ranging from terrestrial ecology to marine biology and can be used as a template for a reader’s own data analysis. Data from all case studies are available from www.highstat.com. Guidance on software is provided in the book.

Auf dem Wege zu Einer Anthropologischen Psychiatrie: Gesammelte Aufsätze

by Jürg Zutt

Aus der Fülle dessen, was uns im Lauf der Jahrzehnte eines Lebens in der Klinik erfahrbar begegnet, was sich uns dort zuspricht, vernehmen wir nur einen kleinen Teil. Das meiste aber zieht an uns vorüber, ohne in uns eine Spur zu hinterlassen. Wir vernehmen zunächst das, worauf wir von unseren Lehrern und der übernommenen Lehre verwiesen werden, was unseren zeit­ bedingten, theoretischen Vorstellungen entspricht. Es zeugt schon von einer guten empirischen Begabung, wenn einer sieht, was ihm keiner gezeigt hat. Gerade dem guten Empiriker drängt sich die Erkenntnis auf, wie vieles, was uns an sich offenbar sein könnte, gleichwohl verborgen, daß unser Wissen immer zur Bescheidenheit mahnendes Stückwerk bleibt, immer im Hinblick auf das Ganze des erfahrbar Begegnenden ein Torso. Schließlich kann es uns drängen, das Geschaute und Gedachte zur Sprache zu bringen, es niederzuschreiben. In dieser freudvoll-mühevollen Arbeit ent­ steht aber ein neues Problem: Nicht jedem ist es gegeben, im Ganzen, in einem ausgewogenen überblick, ohne sich in Einzelheiten zu verlieren und ohne über Problematisches oberflächlich hinwegzugehen, das zu sagen, was er sagen sollte und möchte. So kommt es dann zu kasuistischen Beiträgen mit Fallinterpretationen, Stellungnahmen zu Einzelfragen, zusammenfassenden Darstellungen größerer Zusammenhänge, die aber alle über sich hinausweisen, insofern sie transparent bleiben, auch für eine im Ganzen individuelle Weise das Begegnende zu erfahren, das Erfahrene zu ordnen und darzustellen. Dem Mißverhältnis von Erfahrbarem und wirklich Erfahrenem entspricht das Mißverhältnis von Sagbarem und wirklich Gesagtem.

Freiheitsverlust und Freiheitsentziehung: Schicksale sogenannter Geisteskranker

by Jürg Zutt

Mit einem Nachtrag: Freiheitsverzicht und Freiheitsgewinn

Anorectal Disease: Contemporary Management

by Massarat Zutshi

This book provides a concise yet comprehensive summary of the current status of the field that guides patient management and stimulate investigative efforts. It is an easy reference for day-to-day anorectal pathology. The text reviews new testing procedures for anorectal diseases and provides new treatment options about anorectal disease both benign and malignant. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information. The text includes highly practical presentations of typical patients seen in the clinical practice of proctology in the form of case presentations with expert analysis and commentary. Example cases would include common but challenging cases such as an anal tumor, chronic anal pain and anal discharge.Anorectal Disease: Contemporary Management is a comprehensive, state-of-the-art review of this field and serves as a valuable resource for residents, clinicians, surgeons and researchers with an interest anorectal disease.

Biologische Probleme der Rassehygiene und die Kulturvölker (Grenzfragen des Nerven- und Seelenlebens)

by Stavros Zurukzoglu

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

Malaria in Colonial South Asia: Uncoupling Disease and Destitution

by Sheila Zurbrigg

This book highlights the role of acute hunger in malaria lethality in colonial South Asia and investigates how this understanding came to be lost in modern medical, epidemic, and historiographic thought. Using the case studies of colonial Punjab, Sri Lanka, and Bengal, it traces the loss of fundamental concepts and language of hunger in the inter-war period with the reductive application of the new specialisms of nutritional science and immunology, and a parallel loss of the distinction between infection (transmission) and morbid disease. The study locates the final demise of the ‘Human Factor’ (hunger) in malaria history within pre- and early post-WW2 international health institutions – the International Health Division of the Rockefeller Foundation and the nascent WHO’s Expert Committee on Malaria. It examines the implications of this epistemic shift for interpreting South Asian health history, and reclaims a broader understanding of common endemic infection (endemiology) as a prime driver, in the context of subsistence precarity, of epidemic mortality history and demographic change. This book will be useful to scholars and researchers of public health, social medicine and social epidemiology, imperial history, epidemic and demographic history, history of medicine, medical sociology, and sociology.

Malaria in Colonial South Asia: Uncoupling Disease and Destitution

by Sheila Zurbrigg

This book highlights the role of acute hunger in malaria lethality in colonial South Asia and investigates how this understanding came to be lost in modern medical, epidemic, and historiographic thought. Using the case studies of colonial Punjab, Sri Lanka, and Bengal, it traces the loss of fundamental concepts and language of hunger in the inter-war period with the reductive application of the new specialisms of nutritional science and immunology, and a parallel loss of the distinction between infection (transmission) and morbid disease. The study locates the final demise of the ‘Human Factor’ (hunger) in malaria history within pre- and early post-WW2 international health institutions – the International Health Division of the Rockefeller Foundation and the nascent WHO’s Expert Committee on Malaria. It examines the implications of this epistemic shift for interpreting South Asian health history, and reclaims a broader understanding of common endemic infection (endemiology) as a prime driver, in the context of subsistence precarity, of epidemic mortality history and demographic change. This book will be useful to scholars and researchers of public health, social medicine and social epidemiology, imperial history, epidemic and demographic history, history of medicine, medical sociology, and sociology.

Behandlung der Verletzungen und Eiterungen an Fingern und Hand

by M. Zur Verth

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

Infections Causing Human Cancer

by Harald zur Hausen

Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. The establishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies. In this book, Professor zur Hausen (Nobel Prize in Physiology/Medicine 2008) provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer. The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart viruses play a role in the development of this type of cancer.

New Method of Identifying Family Related Skulls: Forensic Medicine, Anthropology, Epigenetics

by Zvonka Zupanic Slavec

If DNA cannot be isolated, don't give up the identification! The author has used for the same purpose methods ranging from physical anthropology to forensic medicine and especially a recent method of comparison of epigenetic traits, which proved to be very useful for the identification of family related skulls in connection with historical and other data. The kinship of 18 identified skulls (buried together in a family vault) is established by comparison of X-ray images of paranasal cavities (frontal and maxillary sinuses, orbital and nasal cavities), the shape and size of which are strongly genetically determined. The comparison also extends to numerous other epigenetic trait similarities on the skulls. It is recommended for: scientists working on human identification and studying heredity, forensic scientists, physical anthropologists, radiologists, stomatologists, paleopathologists, geneticists, historians and many others.

Animals, Political Liberalism and Public Reason

by Federico Zuolo

This book explores the problem of disagreement concerning the treatment of animals in a liberal society. Current laws include an unprecedented concern for animal welfare, yet disagreement remains pervasive. This issue has so far been neglected both in political philosophy and animal ethics. Although starting from disagreement has been the hallmark of many politically liberal theories, none have been devoted to the treatment of animals, and conversely, most theories in animal ethics do not take the disagreement on this issue seriously. Bridging this divide with a change of perspective, Zuolo argues that we should begin from the disagreement on the moral status of animals and the treatment we owe them. Reconstructing the epistemic nature of disagreement about animals, Zuolo proposes a novel form of public justification to find principles acceptable to all. By setting out a unified framework which honours the liberal principles of respect for diversity, a robust liberal political theory capable of dealing with diverse forms of disagreement, and even some forms of radical dissent, is achieved.

Zur Physiologie und Hygiene der Luftfahrt: 3. Heft (Luftfahrt und Wissenschaft #3)

by N. Zuntz

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

Designing Exoskeletons

by Luis Adrian Zuñiga-Aviles Giorgio Mackenzie Cruz-Martinez

Designing Exoskeletons focuses on developing exoskeletons, following the lifecycle of an exoskeleton from design to manufacture. It demonstrates how modern technologies can be used at every stage of the process, such as design methodologies, CAD/CAE/CAM software, rapid prototyping, test benches, materials, heat and surface treatments, and manufacturing processes. Several case studies are presented to provide detailed considerations on developing specific topics. Exoskeletons are designed to provide work-power, rehabilitation, and assistive training to sports and military applications. Beginning with a review of the history of exoskeletons from ancient to modern times, the book builds on this by mapping out recent innovations and state-of-the-art technologies that utilize advanced exoskeleton design. Presenting a comprehensive guide to computer design tools used by bioengineers, the book demonstrates the capabilities of modern software at all stages of the process, looking at computer-aided design, manufacturing, and engineering. It also details the materials used to create exoskeletons, notably steels, engineering polymers, composites, and emerging materials. Manufacturing processes, both conventional and unconventional are discussed—for example, casting, powder metallurgy, additive manufacturing, and heat and surface treatments. This book is essential reading for those in the field of exoskeletons, such as designers, workers in research and development, engineering and design students, and those interested in robotics applied to medical devices.

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