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Low-Dose Radiation Effects on Animals and Ecosystems: Long-Term Study on the Fukushima Nuclear Accident
by Manabu FukumotoThis open access book summarizes the latest scientific findings regarding the biological effects of the Fukushima Daiichi Nuclear Power Plant (FNPP) accident in 2011.Various cases of changes in animals and organisms have been reported since the FNPP accident. However, it is often unknown whether they are actually due to radiation, since the dose or dose-rate are not necessarily associated with the changes observed. This book brings together the works of radiation biologists and ecologists to provide reliable radioecology data and gives insight into future radioprotection.The book examines the environmental pollution and radiation exposure, and contains valuable data from abandoned livestock in the ex-evacuation zone and from wild animals including invertebrates and vertebrates, aqueous and terrestrial animals, and plants that are subjected to long-term exposure in the area still affected by radiation. It also analyzes dose evaluation, and offers new perspectives gained from the accident, as well as an overview for future studies to promote radioprotection of humans and the ecosystem.Since the biological impact of radiation is influenced by various factors, it is difficult to scientifically define the effects of low-dose/low-dose-rate radiation. However, the detailed research data presented can be combined with the latest scientific and technological advances, such as artificial intelligence, to provide new insights in the future.This book is a unique and valuable resource for researchers, professionals and anyone interested in the impact of exposure to radiation or contamination with radioactive materials.
Food Security in Small Island States
by John Connell Kristen LowittThis book provides a contemporary overview of the social-ecological and economic vulnerabilities that produce food and nutrition insecurity in various small island contexts, including both high islands and atolls, from the Pacific to the Caribbean. It examines the historical and contemporary circumstances that have accompanied the shift from subsistence production to the consumption of imported, processed foods and drinks, and the impact of this transition on nutrition and the rise of non-communicable diseases. It also assesses the challenges involved in reversing this trend, and how more effective social and economic policies, agricultural and fisheries strategies, and governance arrangements could promote more resilient and sustainable small island food systems. It offers both theoretical and practical perspectives, and brings together a broad range of policy areas, e.g. agriculture, food, commerce, health, planning and socio-economic policy.Given its scope, the book offers a valuable resource for a range of disciplines in a number of regional contexts, and for the growing number of scholars and practitioners working on and in small island states. It will be of particular value as the first book to examine the diversity and commonalities of island states around the globe as they confront issues of food security.
Oxidative Stress in Heart Diseases
by Sajal Chakraborti Naranjan S Dhalla Nirmal K Ganguly Madhu DikshitThis book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
Fresh Water Pollution Dynamics and Remediation
by Humaira Qadri Rouf Ahmad Bhat Mohammad Aneesul Mehmood Gowhar Hamid DarFreshwater is a finite resource and is being deteriorated directly and indirectly by anthropogenic pressures. Preserving the quality and availability of freshwater resources is becoming one of the most pressing environmental challenges on the international horizon. To ensure the preservation as well as availability of freshwater resources, there is a need to understand the ecology of the freshwater systems, pollution problems, their impacts, restoration techniques to be opted and the conservation measures. In this backdrop the present book on ‘Freshwater Pollution Dynamics and Remediation’ has been compiled. The book provides an understanding about the present state of art, pollution impacts including the changes in the environmental quality as well as the shift in the aquatic biological communities of the fragile freshwater ecosystems. Besides, the impact of deteriorating quality of the freshwater ecosystems on the animal and human health is also discussed in detail. This book provides a comprehensive account of the techniques based on updated research in biotechnology, bio-remediation, phyto-remediation and nano-bioremediation. The role of biosorpers and biofilms as a remediation tool has also been detailed. The book is a ready reference for researchers, scientists and educators who are involved in the freshwater pollution, remediation and management studies. The book editors with an expertise in diverse research fields in freshwater ecosystems have congregated the most inclusive research accounts on the freshwater pollution and remediation and thus developed a repository of diverse knowledge on the subject
Nuclear Emergencies: A Holistic Approach to Preparedness and Response (Current Topics in Environmental Health and Preventive Medicine)
by Georg Steinhauser Akio Koizumi Katsumi ShozugawaThis book discusses nuclear events that may become imminent threats to the fabric of our society, and elucidates strategies for preventing these threats or mitigating their adverse effects. It addresses multidisciplinary aspects of various nuclear emergencies, including nuclear accidents, terror attacks involving nuclear materials, illicit trafficking of nuclear materials, and problems related to nuclear forensics and strikes with nuclear weapons/warheads. Very often, nuclear emergencies are only discussed within certain, specific communities. However, this volume brings together experts from various fields to provide a more holistic approach to the problem. Physical, chemical, environmental, social, and medical scientists, together with representatives from the media and authorities, present their views on and strategies for events that cause fear and anxiety among the public – an aspect that can be even more threatening than the direct health effects. The book offers a valuable guide for nuclear scientists, such as radioecologists, health physicists, radioanalytical scientists and nuclear engineers, as well as decision-makers and national/international authorities.
Differential Diagnosis of Fracture
by Yingze ZhangThis book covers diagnostic images of common and rare fractures for nearly every part of the human body, based on a large number of clinical cases. The highlight of this book is that both of three-dimensional X-ray images and CT/MRI images of thousands of fracture cases are presented for comparison and further discussion, according to the framework of AO classification. The first chapter gives a general introduction of various diagnostic imaging techniques for fractures, with attention to their advantages and disadvantages. The following chapters present detailed radiological images of upper extremity fractures, lower extremity fractures, axial skeleton fractures, and epiphyseal lesions. It helps readers to recognize the difference between various diagnostic techniques, and to select optimal imaging techniques. With the illustrative figures, this book is a valuable tool to orthopaedist, radiologists, trauma surgeons, emergency room doctors, professional clinical staff, and medical students.
Stereo Atlas of Vitreoretinal Diseases
by Hanyi MinThis book introduces up-to-date knowledge of vitreal and retinal diseases with color fundus illustrations. The retinal layers of different lesions normally look like a single plane for junior doctors in Ophthalmology. With the help of the fundus camera, the stereo color images with different shooting angles are taken and the retina looks vivid and stereoscopic in the photograph. Although the technology of "deciphering" retina diseases is constantly advancing, the stereo fundus photography (SFP) is still indispensable, which can not only reveals the retina stereoscopically and comprehensively, but also has been the gold standard for certain diseases, such as glaucoma and retina angiomatous proliferation (RAP). Meanwhile, the equipment demands for SFP are not so high and can be easily promoted in the grass-roots hospitals. In this book, we carefully collected and organized more than 300 stereo color fundus images and angiography pictures of various vitreal and retinal diseases for readers to recognize the three dimensional features at first glance, such as retinal bleeding at different layers, optic disc change of glaucoma, macular diseases, tumors, RAP and polypoidal choroidal vasculopathy (PCV).
Oxidative Stress in Lung Diseases: Volume 1
by Sajal Chakraborti Tapati Chakraborti Salil Kumar Das Dhrubajyoti ChattopadhyayThis first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.
Health, Safety and Well-Being of Workers in the Informal Sector in India: Lessons for Emerging Economies
by Sigamani Panneer Sanghmitra S. Acharya Nagarajan SivakamiThis book focuses on the core problems of occupational health, safety and well-being of workers in the informal sector in developing countries, where it accounts for most of the rural labour force and a substantial percentage of the urban labour force. The sector is characterised by low incomes, unstable employment and lack of protection in the form of legislation/policies or trade unions. Though some health and problem-solving measures have been introduced, a focused academic effort to address the problems confronting workers in the unorganised sector, or informal economy, is lacking.The book evaluates workers’ physical and mental health in the context of labour migration, social inclusion of minorities and the differently abled, provisions for women workers, demonetisation, occupational safety for hazardous work, and in connection with various areas of informal work, e.g. agriculture, construction, transportation, sanitation, tanning, the tobacco industry, powerloom industry, surrogacy, and self-employment. It provides a well-rounded description of an analytical reflection on the challenges these workers face and focuses on social policy changes to help alleviate them. Accordingly, it offers a valuable asset for researchers and students interested in development studies, the sociology of work, health and labour economics, public health, and social work.
In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials (Current Topics in Environmental Health and Preventive Medicine)
by Toru Takebayashi Robert Landsiedel Masashi GamoThis edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomaterials and related issues. For each screening method, it provides up-to-date information on the test procedures, interpretation of the test results, useful applications, and related technologies. In view of the increasing variety of nanomaterials in practical use, the book offers a basis for building a framework for grouping and read-across assessments of nanomaterials. With contributions by academic and industrial experts, In vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials is a pragmatic reference resource for readers who are responsible for assessing the safety of nanomaterials in R&D and business, as well as researchers.
Autistic Community and the Neurodiversity Movement: Stories from the Frontline
by Steven K. KappThis open access book marks the first historical overview of the autism rights branch of the neurodiversity movement, describing the activities and rationales of key leaders in their own words since it organized into a unique community in 1992. Sandwiched by editorial chapters that include critical analysis, the book contains 19 chapters by 21 authors about the forming of the autistic community and neurodiversity movement, progress in their influence on the broader autism community and field, and their possible threshold of the advocacy establishment. The actions covered are legendary in the autistic community, including manifestos such as “Don’t Mourn for Us”, mailing lists, websites or webpages, conferences, issue campaigns, academic project and journal, a book, and advisory roles. These actions have shifted the landscape toward viewing autism in social terms of human rights and identity to accept, rather than as a medical collection of deficits and symptoms to cure.
Koku in Food Science and Physiology: Recent Research on a Key Concept in Palatability
by Toshihide Nishimura Motonaka KurodaThis is the first book to explore the science underlying the concept of “koku”, which is central to an understanding of the palatability of food within Japanese cuisine and is attracting increasing interest among food scientists and professionals worldwide. Koku may be defined as the sensation that results from the complexity of the food (i.e., its richness or body), its lingering aftertaste or persistence, and its heartiness in terms of taste, aroma, and texture. A variety of substances have been found to impact significantly on koku, including umami substances, phytosterols, certain aromatic compounds, and kokumi substances. In Koku – Food Science and Physiology, readers will find full explanation of the conceptual aspects and the latest research results on a wide range of topics, including the relevant flavor chemistry and sensory analysis. Written by leading scientists in the field, the book will be a valuable resource for students and researchers in the fields of food chemistry, nutritional science, taste physiology, and neuroscience, as well as for professionals in the food industry.
Glaucoma (Current Practices in Ophthalmology)
by Parul IchhpujaniThis book covers all the latest aspects of what’s happening in all the micro-fields of glaucoma. The chapters cover pathogenesis, structural and functional tests, and medical, laser and surgical therapies. An entire chapter is devoted to the future of glaucoma management. All the chapters are supported with illustrations to enhance understanding of the developments.A lot of innovations are happening in the field of basic research, pharmacology, surgical devices and imaging equipment for glaucoma.As part of the series “Current Practices in Ophthalmology” this volume is meant for residents, fellows-in-training, generalist ophthalmologists and specialists alike.
Updates on Myopia: A Clinical Perspective
by Marcus Ang Tien Y. WongThis book is open access under a CC BY 4.0 license.This open access book discusses basic clinical concepts of myopia, prevention of progression and surgical treatments for myopia and pathological myopia. It also summarises the latest evidence and best practices for managing myopia, high myopia and its complications. Written by leading experts, the book addresses clinical diagnosis and interpretation of imaging modalities, and various complications of myopia such as glaucoma, choroidal neovascularization, retinal degeneration and cataracts. It is a valuable comprehensive resource for general and sub-specialist ophthalmologists as well as residents and ophthalmologists in training.
Microbiome in Plant Health and Disease: Challenges and Opportunities
by Vivek Kumar Ram Prasad Manoj Kumar Devendra K. ChoudharyThe book discusses the complex interactions between plants and their associated microbial communities. It also elucidates the ways in which these microbiomes are connected with the plant system, and how they affect plant health. The different chapters describe how microbiomes affect plants with regard to immunity, disease conditions, stress management and productivity. In addition, the book describes how an ‘additional plant genome’ functions as a whole organ system of the host, and how it presents both challenges and opportunities for the plant system. Moreover, the book includes a dedicated section on using omics tools to understand these interactions, and on exploiting them to their full potential.
Atmospheric Reactive Nitrogen in China: Emission, Deposition and Environmental Impacts
by Xuejun Liu Enzai DuAtmospheric reactive nitrogen (N) emissions, as an important component of global N cycle, have been significantly altered by anthropogenic activities, and consequently have had a global impact on air pollution and ecosystem services. Due to rapid agricultural, industrial, and urban development, China has been experiencing an increase in reactive N emissions and deposition since the late 1970s. Based on a literature review, this book summarizes recent research on: 1) atmospheric reactive N in China from a global perspective (Chapter 1); 2) atmospheric reactive N emissions, deposition and budget in China (Chapters 2-5); 3) the contribution of atmospheric reactive N to air pollution (e.g., haze, surface O3, and acid deposition) (Chapters 6-8); 4) the impacts of N deposition on sensitive ecosystems (e.g., forests, grasslands, deserts and lakes) (Chapters 9-12); and 5) the regulatory strategies for mitigation of atmospheric reactive N pollution from agricultural and non-agricultural sectors in China (Chapters 13-14). As such it offers graduate students, researchers, educators in agricultural, ecological and environmental sciences, and policy makers a glimpse of the environmental issues related to reactive N in China .
HIV/AIDS in China: Epidemiology, Prevention and Treatment (Public Health In China Ser. #1)
by Zunyou Wu Yu Wang Roger Detels Marc Bulterys Jennifer M. McGooganWith HIV becoming the leading cause of infectious-disease mortality in Mainland China, this book focuses on tackling HIV/AIDS in the face of rapid political and economic change in China. Featuring contributions by over a dozen leading figures in the field, this book is the go-to text for any student or reader interested in how national and international organizations’ are attempting to control this epidemic. The book includes chapters on the epidemiology, treatment, and prevention of HIV, as well as several chapters that discuss in detail specific provincial- and national-level programs to control and treat HIV. It chronicles the Chinese government’s amazing about-face, as it replaced underfunded, non-evidence based policy decisions with successful, science-based approaches to disease control and prevention, including the adoption of once controversial needle-exchange programs and the establishment of a national HIV/AIDS data registry. It measures the success of national policy decisions, the implementation of treatment policies, and discusses the difficulty of accessing high-risk communities, including people who inject drugs, sex workers, and men who have sex with men – groups not easy to reach, study, engage in prevention programs, or treatment, for fear of stigmatization and loss of social status. Further, it documents the spread of HIV to other provinces, and the tragedy that befell repeat plasma donors in Henan and other poor provinces, where reused or improperly sterilized lab equipment caused some villages to have epidemic-level incidence rates. This book represents a positive contribution to the field of AIDS research, making vital, new information available to an interested readership.
Neuro-ophthalmic Disorders (Current Practices in Ophthalmology)
by Preeti Patil ChhablaniThis book discusses in detail the major advances in the field of neuro-ophthalmology. Based on the latest research from across the globe, it highlights recent developments in all areas of neuro-ophthalmology, including optic neuritis and the associated demyelinating diseases – especially the changing paradigms in the diagnosis and management of multiple sclerosis and neuromyelitis optica. It also covers the various types of hereditary optic neuropathies as well as nystagmus and its management. In order to provide comprehensive information in a single volume, it addresses topics of interest in pediatric neuro-ophthalmology, such as pediatric optic neuritis and cortical visual impairment, innovations in the management of ocular motility disorders and other disorders of the optic nerve and central nervous system, including ischemic neuropathies and idiopathic intracranial hypertension.This book provides a one-stop source of information on all key topics of neuro-ophthalmology, enabling trainee fellows and practitioners to keep abreast of the current thoughts in this field.As part of the series “Current Practices in Ophthalmology” this volume is intended for residents and fellows-in-training, as well as generalist and specialist ophthalmologists alike.
Orbit and Oculoplastics: Newer Trends (Current Practices in Ophthalmology)
by Adit Gupta Prerana TahilianiThis book covers the advances in the field of ophthalmic plastic and orbital surgery. This book aims at educating the general and specialist ophthalmologists and residents about the various facets that this niche subspecialty has to offer in the future. It covers the latest evidence-based approach in the diagnosis and management of various oculoplastic disorders. Chapters are supplemented with ample illustrations and well labelled diagrams wherever necessary. Chapters include key topics such as imaging, orbital decompression, lacrimal surgery, and orbital trauma. Chapters on navigation-guided orbital surgery, oculo-facial aesthetics, socket surgery, and targeted therapies on peri-ocular and orbital malignancies complete the coverage. A special chapter on photographic documentation in oculoplastics guides readers on how to capture the images for future reference and work.As part of the series “Current Practices in Ophthalmology” this volume is meant for residents, fellows-in-training, generalist ophthalmologists and specialists alike.
Inflammatory and Infectious Ocular Disorders (Retina Atlas)
by Hyeong Gon YuThis atlas covers most ocular inflammatory and infectious diseases of importance with clinical significance. It includes chapters on non-infectious diseases and chapters on infectious diseases. For each chapter, essential information regarding the clinical features, diagnosis, and management is described in the text based on the up-to-date knowledge, and more than 240 carefully selected photographs are provided. World-famous experts in this field have included as many as valuable photographs of patients as possible. New imaging tests of ultra-wide field retinal images and high-resolution optical coherence tomography are included in addition to conventional fundus photos and fluorescein angiographs. Especially, chapters on infectious diseases provide invaluable photos of rare but clinically important diseases. Designed to assist in the diagnosis and treatment of ocular inflammation and infection, this book is meant for the retina specialist, researchers of ocular inflammation, general ophthalmologist, resident and retina fellow. Inflammatory and Infectious Ocular Disorders atlas is one of the nine volumes of the series Retina Atlas. This series provides global perspective on vitreoretinal diseases, covering imaging basics, retinal vascular disease, macular disorders, ocular inflammatory and infectious disorders, retinal degeneration, surgical retina, ocular oncology, pediatric retina and trauma. This comprehensive atlas is spread over 9 volumes and about 100 chapters, covering validated and comprehensive information on retinal disorders.
Trauma and Miscellaneous Disorders in Retina (Retina Atlas)
by Eduardo Büchele Rodrigues Carsten Helmut Meyer Eduardo TomazoniThis atlas presents common and rare traumatic conditions of the retina and related intraocular tissues (choroidal rupture, commotio retinae, intraocular foreign body). It also covers intraocular tumors and congenital conditions such as myelinated retinal nerve fibers. Including numerous high-quality figures using various modalities, the book reviews the basic management principles in a reader-friendly style to help readers gain a better understanding of the diseases discussed.Trauma and Miscellaneous Disorders in Retina is one of nine volumes in the series Retina Atlas. This series provides comprehensive information on vitreoretinal diseases, covering imaging basics, retinal vascular disease, ocular inflammatory disease, retinal degeneration, retinal surgery, macular disorders, ocular oncology, pediatric retina and trauma.
International Handbook of Elder Abuse and Mistreatment
by Mala Kapur ShankardassThis first-of-its-kind work on elder abuse and mistreatment provides a comprehensive and up-to-date overview of the subject. Covering almost all regions of the world, it highlights different dimensions of elder abuse and mistreatment in terms of their prevalence, incidence, prevention, treatment, management and response from governments and civil society, academic and research communities, and society in general. Written by international specialists from various disciplinary and presenting the latest findings and data, the handbook includes sections on the Americas; the Caribbean; Europe; Central, West and South Asia; East Asia and Asia-Pacific; and Africa. The chapters offer clarity on the concept and forms of elder abuse and neglect, discuss research methodology, and provide policy options, legislative solutions and programmatic responses to give relief to older people as victims of abuse and neglect as well as to deal with the perpetrators. This book is intended for a wide range of students and researchers interested in aging, from sociology, to social work, community medicine, public health, clinical psychology, and human rights/law.
Laparoscopic Pelvic Anatomy in Females: Applied Surgical Principles
by Shailesh Puntambekar Sambit M. Nanda Kajal ParikhThis book offers a concise and easy-to-understand overview of facts and concepts in pelvic anatomy. Laparoscopy provides good vision in a limited field, which means that surgeons have to rely on their anatomical knowledge of what structures lie in the vicinity and which structures need to be preserved. Focusing on surgical anatomy, the book helps laparoscopic surgeons better understand the female pelvic structures so improve their surgical skills.
Protein Allostery in Drug Discovery (Advances in Experimental Medicine and Biology #1163)
by Jian Zhang Ruth NussinovThe book focuses on protein allostery in drug discovery. Allosteric regulation, ʹthe second secret of lifeʹ, fine-tunes virtually most biological processes and controls physiological activities. Allostery can both cause human diseases and contribute to development of new therapeutics. Allosteric drugs exhibit unparalleled advantages compared to conventional orthosteric drugs, rendering the development of allosteric modulators as an appealing strategy to improve selectivity and pharmacodynamic properties in drug leads. The Series delineates the immense significance of protein allostery—as demonstrated by recent advances in the repertoires of the concept, its mechanistic mechanisms, and networks, characteristics of allosteric proteins, modulators, and sites, development of computational and experimental methods to predict allosteric sites, small-molecule allosteric modulators of protein kinases and G-protein coupled receptors, engineering allostery, and the underlying role of allostery in precise medicine. Comprehensive understanding of protein allostery is expected to guide the rational design of allosteric drugs for the treatment of human diseases. The book would be useful for scientists and students in the field of protein science and Pharmacology etc.
Development of Novel Stability Indicating Methods Using Liquid Chromatography
by Mukesh Maithani Parveen BansalReversed-phase high-performance liquid chromatography (RP-HPLC) has become the most widely used method for pharmaceutical analysis, as it ensures accuracy, specificity and reproducibility for the quantification of drugs, while avoiding interference from any of the excipients that are normally present in pharmaceutical dosage forms. This book presents a simple methodology for developing stability-indicating methods and offers a ‘how-to guide’ to creating novel stability-indicating methods using liquid chromatography. It provides the detailed information needed to devise a stability-indicating method for drug substances and drug products that comply with international regulatory guidelines. As such, it is a must-read for anyone engaged in analytical and bioanalytical chemistry: professionals at reference, test, and control laboratories; students and academics at research laboratories, and scientists working for chemical, pharmaceutical, and biotechnology companies.