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Enzymology and Molecular Biology of Carbonyl Metabolism 3 (Advances in Experimental Medicine and Biology #284)
by David W. Crabb Henry Weiner Bendicht WermuthThe Fifth International Workshop on the Enzymology and Molecular Biology of Carbonyl Metabolism was held at Purdue University in June, 1990. This represents the fifth time that I had the privilege of organizing the scientific program. It was the first time that I actually hosted the meeting. I wish to salute my four previous co-organizers and the thousands of scientists who have hosted other meetings. It is much easier to arrange the scientific program and edit the proceedings. No local organization could occur without the help of ones research group and, in this case, my wife. I sincerely thank Esther and my research group for their advise and help. At this Workshop, similar to the preceeding ones, much new information was presented. It was apparent how molecular biological techniques were influencing the direction of the research on the three families of enzymes discussed. It also was apparent that not all biochemical problems could be solved by using these techniques. Many of the presentations showed how important advances still could be made using more traditional biochemical approaches.
Epidemiology and Biology of Multiple Myeloma
by MichaelPotter G. IrisObramsOn March 27, 1990, the National Cancer Institute sponsored a workshop on the epidemiology of multiple myeloma, held at the National Institutes of Health. This book comprises articles prepared by participants in this work shop. Discussed in these papers are: the descriptive and analytic epidemi ology, differences in risk factors between blacks and whites, monoclonal gammopathies and their progression, and hypotheses regarding the etiology and pathogenesis of multiple myeloma. Several epidemiologic research areas received particular attention during this workshop, and are reviewed in detail in this volume. There have been striking increases in the incidence of multiple myeloma over the past thirty years, especially among older individuals and blacks, which may not be entirely explained by changes in diagnostic capabilities. Occupational and environmental exposures have been associated with an increased risk of multiple myeloma, including farming exposures, occupational exposure to petroleum and rubber processing, exposure to ionizing radiation, and asso ciations with persistent virus infections. The most striking epidemiological finding is reflected in the differences in incidence rates of multiple myeloma which are twice as high in blacks as compared with whites. Further, since 1950 the mortality rates for multiple myeloma have quadrupled in blacks while doubling for whites. Among hematopoietic malignancies, multiple myeloma is the only one with increased incidence and mortality rates among blacks. 1\vo major possibilities for explaining ethnic/racial differences in suscepti bility to multiple myeloma are genetic and environmental factors.
Epidemiology of Peripheral Vascular Disease
by F. G. R.FowkesMajor epidemiologists from the UK, USA and Europe contribute to the first ever, much needed comprehensive review of the epidemiology of peripheral vascular disease in the lower limbs.
The Epigenesis of Mind: Essays on Biology and Cognition (Jean Piaget Symposia Series)
by Susan Carey Rochel GelmanReflecting the focus of a Jean Piaget Symposium entitled Biology and Knowledge: Structural Constraints on Development, this volume presents many of the emergent themes discussed. Among these themes are: Structural constraints on cognitive development and learning come in many shapes and forms and involve appeal to more than one level of analysis. To postulate innate knowledge is not to deny that humans can acquire new concepts. It is unlikely that there is only one learning mechanism, even if one prefers to work with general as opposed to domain-specific mechanisms. The problems of induction with respect to concept acquisition are even harder than originally thought.
The Epigenesis of Mind: Essays on Biology and Cognition (Jean Piaget Symposia Series)
by Susan Carey Rochel GelmanReflecting the focus of a Jean Piaget Symposium entitled Biology and Knowledge: Structural Constraints on Development, this volume presents many of the emergent themes discussed. Among these themes are: Structural constraints on cognitive development and learning come in many shapes and forms and involve appeal to more than one level of analysis. To postulate innate knowledge is not to deny that humans can acquire new concepts. It is unlikely that there is only one learning mechanism, even if one prefers to work with general as opposed to domain-specific mechanisms. The problems of induction with respect to concept acquisition are even harder than originally thought.
Epistemics and Economics: A Critique of Economic Doctrines
by G. L. ShackleIt is Shackle's view that human conduct is chosen with a view to its consequences. But these are in the future, which cannot be directly known. Expectation will confine itself to what is deemed possible, but this leaves it free to entertain widely diverse and rival hypotheses. How can such skeins of mutually conflicting ideas serve the formation of individual or institutional policy? This is the chief question this book examines.
Epistemics and Economics: A Critique of Economic Doctrines
by G. L. ShackleIt is Shackle's view that human conduct is chosen with a view to its consequences. But these are in the future, which cannot be directly known. Expectation will confine itself to what is deemed possible, but this leaves it free to entertain widely diverse and rival hypotheses. How can such skeins of mutually conflicting ideas serve the formation of individual or institutional policy? This is the chief question this book examines.
Epistemological Foundations of Mathematical Experience (Recent Research in Psychology)
by Leslie P. SteffeOn the 26th, 27th, and 28th of February of 1988, a conference was held on the epistemological foundations of mathematical experience as part of the activities of NSF Grant No. MDR-8550463, Child Generated Multiplying and Dividing Algorithms: A Teaching Experiment. I had just completed work on the book Construction of Arithmetical Meanings and Strategies with Paul Cobb and Ernst von Glasersfeld and felt that substantial progress had been made in understanding the early numerical experiences of the six children who were the subjects of study in that book. While the book was in preparation, I was also engaged in the teaching experiment on mUltiplying and dividing algorithms. My focus in this teaching experiment was on investigating the mathematical experiences of the involved children and on developing a language through which those experiences might be expressed. However, prior to immersing myself in the conceptual analysis of the mathematical experiences of the children, I felt that it was crucial to critically evaluate the progress that we felt we had made in our earlier work. It was toward achieving this goal that I organized the conference. When trying to understand the mathematical experiences of a child, one can do no better than to interact with the child in a mathematical context guided by the intention to specify the child's current knowledge and the progress the child might make.
Epistemology and Cognition (Studies in Cognitive Systems #6)
by James H. FetzerThis series will include monographs and collections of studies devoted to the investigation and exploration of knowledge, information, and data-processing systems of all kinds, no matter whether human, (other) animal, or machine. Its scope is intended to span the full range of interest from classical problems in the philosophy of mind and philosophical psychology through issues in cognitive psychology and sociobiology (concerning the mental powers of other species) to ideas related to artificial intelligence and computer science. While primary emphasis will be placed upon theoretical, conceptual, and epistemological aspects of these problems and domains, empirical, experimen tal, and methodological studies will also appear from time to time. The present volume reflects the kind of insights that can be obtained when research workers in philosophy, artificial intelligence, and computer science explore problems of common concern. The issues here tend to fall into two broad but varied sets, namely: those concerned with content and concepts, on the one hand, and those concerned with semantics and epistemology, on the other. The collection begins with a prologue that focuses upon the relations between connectionism and alternative conceptions of nativism and ends with an epilogue that examines the significance of alternative conceptions of the Frame Problem for artificial intelligence. Because these papers are rich and diverse, they ought to appeal to a wide and heterogeneous audience. J.H.F.
Epistle to the Ephesians: A Commentary
by Rudolf SchnackenburgA classic ecumenical commentary on Ephesians. In addition to detailed exegesis, Schnackenburg pays special attention to the history of interpretation of Ephesians, taking account of comparative material in the history of religion and, at the end of each exegetical section, shows how findings are relevant for today. The theological focus is the concept of the church, giving rise to ecumenical discussion about ministry and office in the church. This commentary has proved invaluable for biblical scholars, clergy and theological students.
Epstein-Barr Virus and Human Disease · 1990 (Experimental Biology and Medicine #24)
by D. V. Ablashi A. T. Huang J. S. Pagano G. R. Pearson C. S. YangThe Epstein-Barr virus (EBV), isolated in 1966, continues to draw worldwide attention as an important human pathogen. Its impor tance is largely related to the continuing accumulation of evidence that implicates EBV as an etiological factor for certain types of human cancer. More recent investigations on this virus have focused on the identity of the viral genes responsible for the different disease mani festations observed following viral infection. It is hoped that by thorough investigation of this virus, clues to how cancer develops from a normal cell will surface. In addition, many of the gene products are now being exploited for the development of new and more sensitive tests for the diagnosis and clinical management of individu als with EBV -associated diseases. Thus, studies on this virus continue to provide new information of importance to our understanding of the malignant process. In an effort to attract both basic and clinical scientists to the same meeting for purposes of scientific exchange and fostering a closer interaction between these individuals, a series of international symposia was initiated in 1984. The first meeting was held in Loutraki, Greece, and was attended by approximately 100 participants. The second international symposium was held in St. Petersburg, Florida, in 1986, and was attended by approximately twice as many partici pants as attended the Loutraki meeting.
Equal in Monastic Profession: Religious Women in Medieval France (Women in Culture and Society)
by Penelope D. JohnsonIn this study of the manner in which medieval nuns lived, Penelope Johnson challenges facile stereotypes of nuns living passively under monastic rule, finding instead that collectively they were empowered by their communal privileges and status to think and act without many of the subordinate attitudes of secular women. In the words of one abbess comparing nuns with monks, they were "different as to their sex but equal in their monastic profession." Johnson researched more than two dozen nunneries in northern France from the eleventh century through the thirteenth century, balancing a qualitative reading of medieval monastic documents with a quantitative analysis of a lengthy thirteenth-century visitation record which allows an important comparison of nuns and monks. A fascinating look at the world of medieval spirituality, this work enriches our understanding of women's role in premodern Europe and in church history.
Equal in Monastic Profession: Religious Women in Medieval France (Women in Culture and Society)
by Penelope D. JohnsonIn this study of the manner in which medieval nuns lived, Penelope Johnson challenges facile stereotypes of nuns living passively under monastic rule, finding instead that collectively they were empowered by their communal privileges and status to think and act without many of the subordinate attitudes of secular women. In the words of one abbess comparing nuns with monks, they were "different as to their sex but equal in their monastic profession." Johnson researched more than two dozen nunneries in northern France from the eleventh century through the thirteenth century, balancing a qualitative reading of medieval monastic documents with a quantitative analysis of a lengthy thirteenth-century visitation record which allows an important comparison of nuns and monks. A fascinating look at the world of medieval spirituality, this work enriches our understanding of women's role in premodern Europe and in church history.
Equality and Liberty: Analyzing Rawls and Nozick
by J. Angelo CorlettEquality and Liberty: Analysing Rawls and Nozick is an indispensable source for those seriously interested in some rigorous assessments of the ideas of America's two most popular political philosophers. The essays in this volume cover a wide range of topics, some engaging each other in their analyses of particular Rawlsian or Nozickian themes. This collection of recent essays brings the student up-to-date concerning some of the more recent developments and assessments of Rawlsian and Nozickian ideas.
Equilibrium and Kinetics in Contact Metamorphism: The Ballachulish Igneous Complex and Its Aureole
by Gerhard Voll Jutta Töpel David R. M. Pattison Friedrich SeifertWith the new global tectonics approach in the Earth Sciences, the quan titative aspects of the dynamics of rock-forming processes came into focus: geologists are no longer satisfied knowing the pressure-tempera ture conditions of the formation of a metamorphic rock or of the emplace ment of a magmatic body, but instead would like to learn the time history of these rocks as well, i. e. , derive the temperature-pressure-time path and relate it to a tectonic process. To achieve this goal, a knowledge of both pressure-temperature-dependent equilibria and the time scales at which these equilibria may be attained are essential. However, the latter kinetic information is much more difficult to retrieve than that on equilibria: whereas equilibria are controlled by state variables, and proper laboratory experiments may be directly applied to equilibrium natural assemblages, kinetics also depends on factors other than state variables, such as grain size, dislocation density, and especially time (rate of heating, duration of annealing, rate of cooling). Extrapolation of kinetic data obtained at high temperatures on laboratory time scales to more realistic lower tempera tures and geological time scales are dangerous because, for example, of possible changes from an intrinsically controlled defect regime to an extrinsic one as temperature is lowered, or from an interface-controlled to a diffusion-controlled reaction mechanism.
Equilibrium Theory in Infinite Dimensional Spaces (Studies in Economic Theory #1)
by M. Ali Khan Nicholas C. YannelisApart from the underlying theme that all the contributions to this volume pertain to models set in an infinite dimensional space, they differ on many counts. Some were written in the early seventies while others are reports of ongoing research done especially with this volume in mind. Some are surveys of material that can, at least at this point in time, be deemed to have attained a satisfactory solution of the problem, while oth ers represent initial forays into an original and novel formulation. Some furnish alternative proofs of known, and by now, classical results, while others can be seen as groping towards and exploring formulations that have not yet reached a definitive form. The subject matter also has a wide leeway, ranging from solution concepts for economies to those for games and also including representation of preferences and discussion of purely mathematical problems, all within the rubric of choice variables belonging to an infinite dimensional space, interpreted as a commodity space or as a strategy space. Thus, this is a collective enterprise in a fairly wide sense of the term and one with the diversity of which we have interfered as little as possible. Our motivation for bringing all of this work under one set of covers was severalfold.
Equity and Choice: An Essay in Economics and Applied Philosophy
by Julian Le GrandOffering a new answer to an age-old problem: the meaning of a just or equitable distribution of resources, Julian Le Grand examines the principal interpretations of equity used by economists and political philosophers. He argues that none captures the essence of the term as well as an alternative conception relating equity to the existence or other
Equity and Choice: An Essay in Economics and Applied Philosophy
by Julian Le GrandOffering a new answer to an age-old problem: the meaning of a just or equitable distribution of resources, Julian Le Grand examines the principal interpretations of equity used by economists and political philosophers. He argues that none captures the essence of the term as well as an alternative conception relating equity to the existence or other
Erectile Dysfunction
by J. H. Abicht W. Bähren G. A. Broderick H. Gall I. Goldstein P. M. Hanno U. Hartmann D. Hauri M. W. Hengeveld R. D. Hesch G. Holzki Udo Jonas K. P. Jünemann F. Kulvelis R. M. Levin F. J. Levine T. F. Lue W. Scherb T. H. Schürmeyer C. Sparwasser J. Staubesand W. D. Steers Christian Stief W. F. Thon K. Van Arsdalen G. Wagner A. J. Wein E. Wespes U. WetterauerThe basic principles of the phenomenon "erection" have been known since the pioneering work of Kolliker, Eckhard and Langley in the nineteenth century. Nonetheless, under the influence of Freud, erectile dysfunction was predominantly at tributed to psychogenic factors. A more liberal perception of sexuality since the 1960s, the development of new and refined diagnostic techniques, and the expansion of basic research activity resulted in a new concept of erectile dysfunction, identifying arteriogenic, venogenic, endocrinologic or myopathic (cavernous smooth muscle dysfunction) factors. From this research other considerations such as autonomic innervation, cavernous endo thelial intactness or impaired neurotransmitter pool are being introduced into routine clinical assessment. A reevaluation of psychogenic etiology with a consequential new concept of psy chogenic impotence is on the rise. In this book the new concepts of basic knowledge on cavernous smooth muscle function and its supraspinal, spinal, and local control; the new diagnostic approaches in psychogenic and autonomic factors; and the new developments of reconstructive therapeutic options for the patient have been tied together. Outstanding and internationally renowned experts in the field of erectile dysfunction have given detailed insight into the latest basic and clinical developments. Well-established diagnostic and thera peutic techniques are presented by experienced colleagues. We hope that this book will help the reader to get an overview of the current concepts of erection. Furthermore, we hope that international collaboration in basic and clinical research in the field of erectile dysfunction will render an update necessary in the near future.
Erfahrung, Erinnerung, Erkenntnis: Untersuchungen zum Wahrheitsbegriff der Hermeneutik Gadamers
by Dieter Teichert
Erfolgsfaktoren in Filialsystemen: Diagnose und Umsetzung im strategischen Controlling
by Christian Kube
Erfolgsorientierte Steuerung kleiner und mittlerer Unternehmen: Funktionale, instrumentelle und organisatorische Aspekte eines größengerechten Controlling-Systems (Betriebswirtschaftliche Studien)
by Peter SchusterDie gesamtwirtschaftliche Bedeutung von kleinen und mittleren Unternehmen ist beachtlich - bezogen auf die Anzahl aller Unternehmen, den Anteil der in ihnen beschäftigten Personen und durch sie realisierten Umsätze sind sie in der Unternehmenspraxis sogar dominierend. Controlling zur Führungsunterstützung gewinnt auch in diesen Unternehmen zunehmend an Bedeutung. Äit der vorliegenden Arbeit wird auf IÄhalte, Funktion, Instrumente und Organisationen eines Controlling für die genannten Unternehmen eingegangeÄb Controlling als Managementaufgabe der Führungkräfte im Unternehmen wird begrifflich präzisiert und abgegrenzt; Bedeutung und Verbreitung von Controlling, Kostenrechnung und Unternehmensplanung in kleinen und mittleren Unternehmen werden untersucht. Mögliche Controllinginstrumente werden entwickelt und dargestellt und ihre größenspezifische Eignung geprüft. Abschließend werden organisatorische Aspekte des Controlling im kleinen und mittleren Unternehmen behandelt, und es wird gezeigt, wie Controlling dort eingeführt und organisatorisch verankert werden kann. Dieses Buch hilft, basierend auf der umfangreichen Literatur zu dem Thema, die von der Wissenschaft entwickelten Erkenntnisse auf kleine und mittlere Unternehmen zu übertragen und liefert einen Lösungsvorschlag für eine wirksame, erfolgsorientierte Unternehmenssteuerung kleiner und mittlerer Unternehmen.
Erfolgsstrategien für Zulieferer: Von der Abhängigkeit zur Partnerschaft Automobil- und Kommunikationsindustrie
by Robert Fieten
Ergonomics, Work and Health
by Stephen PheasantThis book introduces the main elements of ergonomics to the medical professions. Written by a well-known ergonomist, it explains how improvements to working (and resting) conditions and design can help both professionals and patients. Such an understanding is essential when dealing with the pains and strains all too frequently encountered by GPs, physiotherapists, OTs, osteopaths, chiropractors and occupational physicians.