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Biological Timekeeping: Clocks, Rhythms and Behaviour

by Vinod Kumar

This book is a concise, comprehensive and up-to-date account of fundamental concepts and potential applications of biological timekeeping mechanisms in animals and humans. It also discusses significant aspects of the organization and importance of timekeeping mechanisms in both groups. Divided into seven sections, it addresses important aspects including fundamental concepts; animal and human clocks; clock interactions; clocks and metabolism and immune functions; pineal, melatonin and timekeeping; and clocks, photoperiodism and seasonal behaviours. The book also focuses on biological clock applications in a 24x7 human society, particularly in connection with life-style associated disorders like obesity and diabetes. It is a valuable resource for advanced undergraduates, researchers and professionals engaged in the study of the science of biological timekeeping.

Mealybugs and their Management in Agricultural and Horticultural crops

by M. Mani C. Shivaraju

This book is a compilation of information on all basic aspects of mealybugs, as well as management strategies for mealybug species affecting different crop plants in different countries. It highlights the latest information on morphology, cytogenetics, taxonomy, molecular characterization, biology, damage, ecology, natural enemies, ant association, control measures, insecticide resistance and pheromones – essential aspects which will equip researchers to pursue further research on mealybugs. The book examines current trends in the management of mealybugs for a variety of agricultural and horticultural crops, forest plants and mulberry in different countries, while also addressing the negative effects of chemical control methods and presenting success stories of mealybug control that utilize their natural enemies. It offers a valuable guide for crop growers, government officials and other stakeholders in the industry, as well as researchers and students engaged in related research and development activities.

Evolutionary Population Genetics of Drosophila ananassae

by Pranveer Singh

This book introduces readers to classical population genetics and the ways in which it can be applied to practical problems, including testing for natural selection, genetic drift, genetic differentiation, population structuring, gene flow and linkage disequilibrium. It provides a comprehensive monograph on the topic, addressing the theory, applications and evolutionary deductions, which are clearly explained using experimental results. It also offers separate chapters on origin, establishment and spread of chromosomal aberrations in populations along with details of culturing, maintaining and using Drosophila ananassae (genetically unique and the most commonly used species along with D. melanogaster) for genetic research. Encompassing topics like genetics, evolution, Drosophila genetics, population genetics, population structuring, natural selection and genetic drift in considerable detail, it provides a valuable resource to undergraduate and postgraduate students, as well as researchers at all level.This book explores some fundamental questions concerning the role of natural selection and genetic drift on the degree of inversion polymorphism. India, with its wide diversity in geo-climatic conditions, provides an excellent platform to conduct such studies. The book showcases sampling records of inversion frequencies in natural Indian populations of D. ananassae that cover more than two decades. It highlights case studies in which sampling data on inversion frequencies was combined with that from earlier surveys, generating a time series that allows the evolutionary dynamics of inversion polymorphism to be explored. Such long time series are rare but nonetheless crucial for studying the evolutionary dynamics of inversion polymorphism. The population-genetic analysis discussed is unprecedented in terms of its temporal (two decades) and spatial (most regions of India covered) scale and investigates the patterns of polymorphic system in D. ananassae to see if there is any temporal divergence. It endeavors to present a holistic picture of inversion polymorphism across the country (India).Chromosomal aberrations, particularly paracentric inversions, are used as a tool for discussing population genetic studies, helping human geneticists, gynecologists and other medical professionals understand why some aberrations are fatal in humans, with affected embryos often not surviving the first trimester of pregnancy, while similar aberrations in Drosophila flies aid in their adaptation to the environmental heterogeneity across the globe.

Sorghum Molecular Breeding

by R. Madhusudhana P. Rajendrakumar J. V. Patil

This book provides an up-to-date overview of international research work on sorghum. Its comprehensive coverage of our current understanding of transgenic development in sorghum and the strategies that are being applied in molecular breeding make this book unique. Important areas such as genetic diversity, QTL mapping, heterosis prediction, genomic and bioinformatics resources, post-genome sequencing developments, molecular markers development using bioinformatics tools, genetic transformation and transgenic research are also addressed. The availability of the genome sequence along with other recent developments in sequencing and genotyping technologies has resulted in considerable advances in the area of sorghum genomics. These in turn have led to the generation of a large number of DNA-based markers and resulted in the identification and fine mapping of QTL associated with grain yield, its component traits, biotic and abiotic stress tolerance as well as grain quality traits in sorghum. Though a large volume of information has accumulated over the years, especially following the sequencing of the sorghum genome, until now it was not available in a single reference resource. This book fills that gap by documenting advances in the genomics and transgenic research in sorghum and presenting critical reviews and future prospects. “Sorghum Molecular Breeding” is an essential guide for students, researchers and managers who are involved in the area of molecular breeding and transgenic research in sorghum and plant biologists in general.

Plant Biology and Biotechnology: Volume I: Plant Diversity, Organization, Function and Improvement

by Bir Bahadur Manchikatla Venkat Rajam Leela Sahijram K. V. Krishnamurthy

This volume offers a much-needed compilation of essential reviews on diverse aspects of plant biology, written by eminent botanists. These reviews effectively cover a wide range of aspects of plant biology that have contemporary relevance. At the same time they integrate classical morphology with molecular biology, physiology with pattern formation, growth with genomics, development with morphogenesis, and classical crop-improvement techniques with modern breeding methodologies. Classical botany has been transformed into cutting-edge plant biology, thus providing the theoretical basis for plant biotechnology.It goes without saying that biotechnology has emerged as a powerful discipline of Biology in the last three decades. Biotechnological tools, techniques and information, used in combination with appropriate planning and execution, have already contributed significantly to economic growth and development. It is estimated that in the next decade or two, products and processes made possible by biotechnology will account for over 60% of worldwide commerce and output. There is, therefore, a need to arrive at a general understanding and common approach to issues related to the nature, possession, conservation and use of biodiversity, as it provides the raw material for biotechnology. More than 90% of the total requirements for the biotechnology industry are contributed by plants and microbes, in terms of goods and services. There are however substantial plant and microbial resources that are waiting for biotechnological exploitation in the near future through effective bioprospection. In order to exploit plants and microbes for their useful products and processes, we need to first understand their basic structure, organization, growth and development, cellular process and overall biology. We also need to identify and develop strategies to improve the productivity of plants.In view of the above, in this two-volume book on plant biology and biotechnology, the first volume is devoted to various aspects of plant biology and crop improvement. It includes 33 chapters contributed by 50 researchers, each of which is an expert in his/her own field of research. The book begins with an introductory chapter that gives a lucid account on the past, present and future of plant biology, thereby providing a perfect historical foundation for the chapters that follow. Four chapters are devoted to details on the structural and developmental aspects of the structures of plants and their principal organs. These chapters provide the molecular biological basis for the regulation of morphogenesis of the form of plants and their organs, involving control at the cellular and tissue levels. Details on biodiversity, the basic raw material for biotechnology, are discussed in a separate chapter, in which emphasis is placed on the genetic, species and ecosystem diversities and their conservation.Since fungi and other microbes form an important component of the overall biodiversity, special attention is paid to the treatment of fungi and other microbes in this volume. Four chapters respectively deal with an overview of fungi, arbuscularmycorrhizae and their relation to the sustenance of plant wealth, diversity and practical applications of mushrooms, and lichens (associated with a photobiont). Microbial endosymbionts associated with plants and phosphate solubilizing microbes in the rhizosphere of plants are exhaustively treated in two separate chapters. The reproductive strategies of bryophytes and an overview on Cycads form the subject matter of another two chapters, thus fulfilling the need to deal with the non-flowering Embryophyte group of plants.Angiosperms, the most important group of plants from a biotechnological perspective, are examined exhaustively in this volume. The chapters on angiosperms provide an overview and cover the genetic basis of flowers development, pre-and post-fertilization reproductive growth and development, seed biology and technology, plant secondary metabolism, photosynthesis, and plant volatile chemicals. A special effort ha

Plant Biology and Biotechnology: Volume II: Plant Genomics and Biotechnology

by Bir Bahadur Manchikatla Venkat Rajam Leela Sahijram K. V. Krishnamurthy

Plant genomics and biotechnology have recently made enormous strides, and hold the potential to benefit agriculture, the environment and various other dimensions of the human endeavor. It is no exaggeration to claim that the twenty-first century belongs to biotechnology. Knowledge generation in this field is growing at a frenetic pace, and keeping abreast of the latest advances and calls on us to double our efforts. Volume II of this two-part series addresses cutting-edge aspects of plant genomics and biotechnology. It includes 37 chapters contributed by over 70 researchers, each of which is an expert in his/her own field of research.Biotechnology has helped to solve many conundrums of plant life that had long remained a mystery to mankind. This volume opens with an exhaustive chapter on the role played by thale cress, Arabidopsis thaliana, which is believed to be the Drosophila of the plant kingdom and an invaluable model plant for understanding basic concepts in plant biology. This is followed by chapters on bioremediation, biofuels and biofertilizers through microalgal manipulation, making it a commercializable prospect; discerning finer details of biotic stress with plant-fungal interactions; and the dynamics of abiotic and biotic stresses, which also figure elsewhere in the book.Breeding crop plants for desirable traits has long been an endeavor of biotechnologists. The significance of molecular markers, marker assisted selection and techniques are covered in a dedicated chapter, as are comprehensive reviews on plant molecular biology, DNA fingerprinting techniques, genomic structure and functional genomics. A chapter dedicated to organellar genomes provides extensive information on this important aspect. Elsewhere in the book, the newly emerging area of epigenetics is presented as seen through the lens of biotechnology, showcasing the pivotal role of DNA methylation in effecting permanent and transient changes to the genome. Exclusive chapters deal with bioinformatics and systems biology. Handy tools for practical applications such as somatic embryogenesis and micropropagation are included to provide frontline information to entrepreneurs, as is a chapter on somaclonal variation.Overcoming barriers to sexual incompatibility has also long been a focus of biotechnology, and is addressed in chapters on wide hybridization and hybrid embryo rescue. Another area of accomplishing triploids through endosperm culture is included as a non-conventional breeding strategy. Secondary metabolite production through tissue cultures, which is of importance to industrial scientists, is also covered.Worldwide exchange of plant genetic material is currently an essential topic, as is conserving natural resources in situ. Chapters on in vitro conservation of extant, threatened and other valuable germplasms, gene banking and related issues are included, along with an extensive account of the biotechnology of spices – the low-volume, high-value crops. Metabolic engineering is another emerging field that provides commercial opportunities. As is well known, there is widespread concern over genetically modified crops among the public. GM crops are covered, as are genetic engineering strategies for combating biotic and abiotic stresses where no other solutions are in sight. RNAi- and micro RNA- based strategies for crop improvement have proved to offer novel alternatives to the existing non-conventional techniques, and detailed information on these aspects is also included. The book’s last five chapters are devoted to presenting the various aspects of environmental, marine, desert and rural biotechnology. The state-of-the-art coverage on a wide range of plant genomics and biotechnology topics will be of great interest to post-graduate students and researchers, including the employees of seed and biotechnology companies, and to instructors in the fields of plant genetics, breeding and biotechnology.

Veterinary Mycology

by Indranil Samanta

This book is a comprehensive overview of the fungi that are clinically relevant for animals and humans. It is divided in three major parts: the first part comprises the history of veterinary and medical mycology, general aspects of morphology, growth, nutrition, reproduction and classification of fungi. In the second part, the etiologic agents of cutaneous, subcutaneous and systemic mycoses are described in detail with special emphasis on emerging and uncommon pathogenic fungi. Each chapter consists of a brief history and the morphology, classification, reproduction, susceptibility to disinfectants, natural habitat, distribution, genome, isolation, growth and colony characteristics, antigenic characteristics, virulence factors. The major diseases and their routes of transmission, pathogenesis, immunity, diagnosis and treatment are also covered. The third part focuses on laboratory diagnosis including clinical sample collection, their processing for fungal isolation, special stains for microscopic visualization, culture media composition and a relevant glossary. Each chapter includes color photographs, schematic diagrams and tables for better understanding.

Advances in Marine and Brackishwater Aquaculture

by Santhanam Perumal Thirunavukkarasu A. R. Perumal Pachiappan

This book compiles the latest findings in the field of marine and brackishwater aquaculture. It covers significant topics such as techniques of culture of live feeds (microalgae, rotifer, Artemia, marine copepod & polychaetes), while also highlighting vital themes like the culture and applications of free and marine sponge associated microbial probiotics, controlled breeding, seed production and culture of commercially important fin and shell fishes. Moreover, the book focuses on the breeding and culture of marine ornamental fishes, sea cucumber and sea urchin and discusses seaweeds culture, aqua feed formulation and nutrition, water quality management in hatchery and grow-out culture systems, fish disease diagnosis and health management and cryopreservation of fish gametes for sustainable aquaculture practices, all from a multidimensional perspective.The global fish production was 154 million tonnes in 2011 which more or less consisted of capture and culture fisheries (FAO, 2012). Roughly 80% of this is from inland-freshwater aquaculture and the remainder from capture fisheries in the marine and brackishwater sector. However, marine and brackishwater catches have recently begun to diminish due to overexploitation, climate change and pollution. The UNEP report affirmed that if the world remains on its current course of overfishing, by 2050, the ocean fish stock could become extinct or no longer commercially viable to exploit. In these circumstances, aquaculture is considered to be a promising sector to fulfill our future protein requirement. However, brackishwater and marine fish production now face serious challenges due to e.g. lack of quality fish seeds, feeds, poor water quality management and diseases. Fisheries and aquaculture sectors play a vital role as potential sources of nutritional security and food safety around the globe. Fish food is rich in protein, vitamins, phosphorous, calcium, zinc, selenium etc. In addition, fish contains omega-3 fatty acids, which help to prevent cardiovascular diseases. Fish food can also provide several health benefits to consumers. The omega 3 fatty acids found in fish can reduce the levels of LDL cholesterol (the “bad” cholesterol) and increase the HDL levels (the “good” cholesterol). Research conducted in Australia has proved that fish consumption can be used to cure hypertension and obesity. It is also reported that people who ate more fish were less prone to asthma and were able to breathe more easily. Omega 3 fish oil or fish consumption can help to prevent three of the most common forms of cancer: breast cancer, colon and prostate cancer. The omega 3 fatty acids present in fish or fish oil induce faster hair growth and prevent hair loss. Since most varieties of fish are rich in protein, eating fish helps to keep hair healthy. Furthermore, fish or fish oil helps in improving the condition of dry skin, giving it a healthy glow. It is useful in treating various skin problems such as eczema, psoriasis, itching, redness of skin, skin lesions and rashes. It is well known that eating fish improves vision and prevents Alzheimer’s and type-2 diabetes, and can combat arthritis. Further, fish oil or fish is good for pregnant women, as the DHA present in it helps in the development of the baby’s eyes and brain. It helps to avoid premature births, low birth weights and miscarriages. In addition, it is widely known that fish can be a good substitute for pulses in cereal-based diets for the poor. The global fish production was roughly 154 million tonnes in 2011 (FAO, 2012). It is estimated that by 2020 global fish requirements will be over 200 million tonnes; as such, innovative technological improvements are called for in order to improve the production and productivity in fisheries. In this context, this book provides valuable information for academics, scientists, researchers, government officials and farmers on innovative technological advances for sustainable fish production using aquaculture methods.The book identifies the main issues and trends in marine and brackishwater aquacultu

Climate Change Impact on Livestock: Adaptation and Mitigation

by Veerasamy Sejian John Gaughan Lance Baumgard Cadaba Prasad

This volume addresses in detail both livestock’s role in climate change and the impacts of climate change on livestock production and reproduction. Apart from these cardinal principles of climate change and livestock production, this volume also examines the various strategies used to mitigate livestock-related GHG emissions, and those which can reduce the impacts of climate change on livestock production and reproduction. Presenting information and case studies collected and analyzed by professionals working in diversified ecological zones, the book explores the influence of climate change on livestock production across the globe. The most significant feature of this book is that it addresses in detail the different adaptation strategies and identifies targets for different stakeholders in connection with climate change and livestock production. Further, it puts forward development plans that will allow the livestock industries to cope with current climate changes and strategies that will mitigate the effects by 2025. Lastly, it provides researchers and policymakers several researchable priorities to help develop economically viable solutions for livestock production with less GHG emissions, promoting a cleaner environment in which human beings and livestock can live in harmony without adverse effects on productivity.Given that livestock production systems are sensitive to climate change and at the same are themselves a contributor to the phenomenon, climate change has the potential to pose an increasingly formidable challenge to the development of the livestock sector. However, there is a dearth of scientific information on adapting livestock production to the changing climate; as such, well-founded reference material on sustaining livestock production systems under the changing climate scenarios in different agro-ecological zones of the world is essential. By methodically and extensively addressing all aspects of climate change and livestock production, this volume offers a valuable tool for understanding the hidden intricacies of climatic stress and its influence on livestock production.

Aquatic Ecosystem: Biodiversity, Ecology And Conservation

by Mamta Rawat Sumit Dookia Chandrakasan Sivaperuman

This book brings together the latest information on the rapid advances and developments in the field of aquatic ecology. India is very rich in terms of biological diversity due to its wide range of habitats and climatic conditions. It is home to as much as 7 per cent of the world’s animal species, although it only accounts for about 2 per cent of the total landmass. The present work on biodiversity, ecology and conservation of aquatic resources represents original research in the field of aquatic biodiversity, wetland ecology and its applications with reference to the country’s aquatic resources. There are 19 chapters, each contributed by an expert in his/her particular field and offering novel approaches to various topics in the area of aquatic ecosystems.

New Horizons in Insect Science: Towards Sustainable Pest Management

by Akshay Kumar Chakravarthy

Insect science is fast changing as insects are evolving to a plethora of newer chemical molecules, climate change, management tactics and transformation of the landscapes. Through the International Conference, the editors have attempted to gather together newer aspects of Insect Sciences like Insect Taxonomy, DNA Barcoding, Physiology, Toxicology, Vectors and their Management, Molecular Biology, RNA interference in Pest Management, Semiochemicals and Pest Management using Host Plant Resistance and Biological Control appropriated especially for the developing world. Both basic and applied aspects of insect science have been included to stimulate comprehensive studies on insect science. The book not only deals with insect science but also environmental and ecological aspects in the hope that the book will be of immense use to students, researchers, extension workers, planners, administrators, farmers and other end users. The Chapters on diversified aspects of Insect Science are contributed by leading scientists for the coming 21st century in which entomology is witnessing a dramatic advancement in management of pests through in-depth investigations. The dimensions of Insect Science covered in the book are pest management approaches that can be adopted worldwide with ascent on sustainability.

Perspectives in Regenerative Medicine

by Ena Ray Banerjee

The information given in this book tries to capture the essence of the sheer dynamicity of the cell along with useful tips on how to address critical rate limiting steps in the process of exploration and investigation of its capacity to regenerate, rebuild and replenish from within. The definitions of stem cells, stemness, and the niche concept continue to undergo revisions. In adult vertebrates, hematopoietic and some non-hematopoietic progenitors are synthesized within specialized niches of bone marrow. They migrate to designated tissues, and are either trans-differentiated or become quiescent and settle down. These form the stem cell niche reservoir in all tissues. Not only the primary hematopoietic tissue but all organs and tissues are also capable of generating progenitors which are either synthesized from these migrants or are direct recruits from other tissues. In the niches, the cells settle down and await their turn to either make more clones like themselves or differentiate and mobilize in an exigency. Thus progenitors are important reserves, to be multiplied and deployed or travel as important message bearing molecules via blood as circulating progenitors which can home to their allocated destinations. Upon reaching, specific integrins and selectins help them “dock” and “port” and they may be reprogrammed to induce further differentiation and help repopulate the denuded tissue. In pulmonary fibrosis and asthma, progenitors from both systemic circulation and local stem cell niches have been found to participate in the myriad ramifications of repair, replacement and regeneration of lost or diseased tissue. Whether they are lung specific or global in origin and role remain to be explored. Research tools, fundamental concepts, techniques, methodologies and standard operating protocols and animal models and human extrapolations, have been discussed in a concise way along with detailed description and discussion on the appropriate rationale to introduce the subject to the casual reader and provide valuable tactical information to the specialist in Regenerative Medicine. I sincerely hope you enjoy the work and appreciate the hard work that has gone into designing and executing elegant experiments by many researchers in the field. The branch is multi-disciplinary and I hope that the readers will not be limited to biologists alone.

Oxidative Stress Mechanisms and their Modulation

by Mohinder Bansal Naveen Kaushal

Research over the years has demonstrated that free radicals mediated oxidative stress lies at the helm of almost all patho-physiological phenomena. These findings emphasize on the need to understand the underlying molecular mechanism(s) and their critical role in the pathogenesis. This book aims to focus on these areas to provide readers a comprehensive outlook about the major redox sensitive pathways and networks involved in various disease conditions. In the first chapter of the book, basic information about the oxidative stress, its generation, its biomarkers and its role in body are discussed. In the next three chapters, the role of oxidative stress in various pathologies ranging from neurological disorders, to cardiovascular diseases, cancers, metabolic diseases and ageing have been described. Chapter 5 cumulatively describes the most important molecular signaling pathways that are affected by reactive oxygen species (ROS). These are the mechanisms which are common denominators in various pathological states. In the next part of the book, various antioxidant strategies to target and mitigate ROS have been discussed with details on the mechanisms. Selenium, being the research focus and interest of the authors for years, the role of selenium as an antioxidant as part of selenoproteins has been included in the book. Finally, the book culminates with authors’ perspective on the future of the redox biology field. Throughout the book, efforts have been made to use simplified language and suitable figures for ease to understand the contents. Although the authors have tried to touch on all the different aspects of oxidative stress in detail, the fact that it is a continuously growing field with updates coming every day, there might be some areas which might not be described in depth. This book is designed for students, young scientists to get acquainted with the redox biology. Overall, this book is a reference to understand the redox regulation of cellular signaling pathways involved in pathogenesis.

Plant Growth Promoting Rhizobacteria for Horticultural Crop Protection

by P. Parvatha Reddy

The use of synthetic pesticides has undoubtedly resulted in the achievement of increased crop production. However, in recent times, there has been a considerable pressure on consumers and farmers to reduce or eliminate the use of synthetic pesticides in horticulture, since fruits and vegetables are consumed afresh. This concern has encouraged looking for better alternatives which are cheaper and eco-friendly than synthetic pesticides. It is well known that plant growth promoting rhizobacteria (PGPR) play an important role in maintaining crop and soil health through versatile mechanisms. There are two main outcomes or effects from beneficial microorganisms: enhanced plant growth and crop protection, both of which represent the two main constraints to agriculture. The information on biomanagement of pests (insect and nematode pests, fungal, bacterial and viral/phytoplasma diseases) of horticultural crops (fruits, vegetables, plantation, spice, tuber, ornamental, medicinal and aromatic crops) using PGPR is very much scattered. There is no book at present which comprehensively and exclusively deals with the above aspects on horticultural crops. The present book deals with biomanagement of pests in horticultural crops in detail using PGPR. The present book deals with biomanagement of pests in horticultural crops in detail using PGPR. The present book is divided into six sections. The first section deals with the importance of PGPR including introduction, potential role of PGPR in agriculture, genera of PGPR, disease management, nematode management, insect pest management, integrated pest management, mechanism of biocontrol, mass production, formulation, delivery and commercialization. Pest management in tropical, sub-tropical and temperate fruit crops is dealt in Section II. The third section deals with pest management in Solanaceous, bulbous, Malvaceous, Cruciferous, Leguminous, Cucurbitaceous, leafy and root and tuber vegetable crops. Pest management in plantation and spice crops is in Section IV. Section V deals with pest management in ornamental, medicinal and aromatic crops. The last section deals with a road map ahead including challenges, future prospective and conclusions. The book is extensively illustrated with excellent quality photographs enhancing the quality of publication. The book is written in lucid style, easy to understand language along with adoptable recommendations involving eco-friendly components of IPM.

Translational Research in Environmental and Occupational Stress

by Shashi Bala Singh Nanduri R. Prabhakar Srinivas N. Pentyala

Cutting edge technologies can propel a simple finding in basic science to a concept that can be of immense value to the society. While applying novel techniques to unravel the mysteries of biological processes, an offshoot of applied branch emerged. This field, which is now widely referred to as Translational Research utilizes basic science findings and translates these findings into innovative concepts for the benefit of mankind. This branch of science has evolved into a multidisciplinary juggernaut encompassing all known fields of science as varied as biomedicine, environment, law, economics, sociology, etc. With the ever increasing interest in this branch and the dreams and aspirations that this field can bring, basic science researchers are now taking a bold step into this new realm, merging different fields of knowledge to come up with novel inventions. This book "Translational research in environmental and occupational stress" provides and insight into the research that led to discoveries, inventions and development of novel technologies which will have a tremendous impact on the future of mankind.

Toxic Effects of Mercury

by Shabnum Nabi

Mercury is widespread in our environment. Methylmercury, an organic form of mercury, can accumulate in the aquatic food chain and lead to high concentrations in predatory fish. When consumed by humans, contaminated fish represent a public health risk. Toxic Effects of Mercury intends to facilitate among its readers the understanding of the importance of mercury pollution in the environment and the health consequences associated with exposure to this metal. The knowledge on methylmercury (MeHg) toxicity collected over the years is undoubtedly robust creating an impression all that is to be learnt about this metal has already been accomplished. However, in large measure, past knowledge has merely laid the ground for interesting questions that have yet to be fully addressed and concepts have yet to be deciphered. One of my major goals was to make a valiant attempt to include state-of-the-art information on the mechanisms of mercury toxicity, describing its effects on cultured cellular systems as well as in whole living organisms, starting from the lessons learned from the tragic events in Minamata Bay, Japan. A special focus of the book is on the neurotoxic effects of MeHg. An understanding at the cellular level is necessary to gather information on the structural and functional alterations induced by MeHg and how they possibly become unmasked and evident at the behavioral level, 32 chapters of the book have been organised having these considerations in mind.This book will provide state-of-the-art information to the graduate students training in toxicology, risk assessors, researchers and medical providers at large. It is aimed to bring the readers updated information on contemporary issues associated with exposure to methylmercury, from its effects on stem cells and neurons to population studies. It is a valuable resource for individuals interested in the public health effects and regulation of mercury. The report provides an excellent example of the implications of decisions in the risk assessment process for a larger audience and is written with the hope that the information will provide better understanding of the mercury problems which confront us.

Connexins: The Gap Junction Proteins (SpringerBriefs in Biochemistry and Molecular Biology)

by Dr. Mahboob Hussain

Gap-junction proteins, connexins are important cellular entities that regulate various facets of cellular physiology. The connexins constitute large family of proteins. The present book provides basic overview about various aspects of connexin proteins. The book has tried to touch the fundamental aspects of connexin family. This book will be useful to broad audience that includes under-and post-graduate students, research scholars, clinicians, etc. The reference section at the end of the book will be helpful for those who seek to know deeper details about this family of proteins.

Biointensive Integrated Pest Management in Horticultural Ecosystems

by P. Parvatha Reddy

Through ‘Green Revolution’ in late 1960s, India achieved self-sufficiency in food production, but still the country has not achieved self-sufficiency in production of horticultural crops. Most of the growth in food production during the green revolution period is attributed to the use of higher levels of fertilizers and pesticides which are continuing to destroy stable traditional ecosystems. The challenge before the crop protection scientist is to increase yields from the existing land without harming the environment and resource base. This can be achieved by adopting eco-friendly Biointensive Integrated Pest Management (BIPM) strategy.BIPM incorporates ecological and economic factors into agricultural system design and decision making, and addresses public concerns about environmental quality and food safety. The benefits of implementing BIPM can include reduced chemical input costs, reduced on-farm and off-farm environmental impacts, and more effective and sustainable pest management. An ecology-based IPM has the potential of decreasing inputs of fuel, machinery, and synthetic chemicals-all of which are energy intensive and increasingly costly in terms of financial and environmental impact. Such reductions will benefit the grower and society.The present book deals with the most recent biointensive integrated approaches for pest management utilizing components such as bioagents [predators, parasitoids and pathogens (bacteria, fungi, viruses)], botanicals (biofumigation, oil cakes, FYM, compost, crop residues, green manuring and other organic amendments), arbuscular mycorrhizal fungi, physical methods (hot water treatment of planting material, soil solarization), cultural methods (crop rotation, summer ploughing, fallowing, intercropping, pruning, mulching, spacing, planting date, trap cropping, etc.), biorational chemicals (pheromones) and resistant cultivars. This book can serve as a useful reference to policy makers, research and extension workers, practicing farmers and students. The material can also be used for teaching post-graduate courses.

Horticultural Nematology

by N.G. Ravichandra

The major objective of this book is to highlight the significance of phytonematodes in horticulture. Detailed and latest information on major aspects of phytonematodes associated exclusively with horticultural crops, which is the need of the day, is lacking. Hence, the book has been written mainly with the objective of providing its readers, comprehensive information on the advanced aspects related to phytonematodes associated with horticultural crops. It also provides basic information on plant parasitic nematodes since it is required for a better understanding of advanced topics. Several popular topics, information on which is already available in plenty, have been avoided. Thus, book explicates both the essential fundamental and advanced aspects pertaining to nematodes associated with horticultural crops.The book is conveniently divided into 13 chapters, which cover latest information on the major fundamental and advanced aspects related to phytonematodes including the role of phytonematodes in horticultural industry, phylogenetic and evolutionary concepts in nematodes, major phytonematodes associated with horticultural crops and their diagnostic keys, symptoms caused by phytonematodes and disease diagnosis, nematode population threshold levels, crop loss assessment, nematode diseases of horticultural crops and their management, nematode disease complexes, genetics of nematode parasitism, important nematological techniques and nematodes of quarantine importance. An exclusive chapter on novel methods of nematode management has been included mainly to provide the information on the latest molecules and novel modes of managing nematodes attacking horticultural crops. Routine nematode management aspects, information on which is already available, have not been discussed; instead, this topic reflects the changing scenario of future nematode management.Hence, this book can serve as a friendly guide to meet the requirements of the students, teachers and researchers interested in these ‘hidden enemies’ of the grower, apart from the research and extension personnel working under Public organizations, officials of State departments of Horticulture, Forestry, field workers and all those concerned and working with plant parasitic nematodes. Appropriate diagrams, convincing tables and suitable graphs/illustrations have been furnished at right places. A complete bibliography has also been included.

The Grape Entomology

by M. Mani C. Shivaraju Narendra S. Kulkarni

Intensive and extensive cultivation of grapes (Vitis vinifera L.) leads to serious pest problem in vineyards in major grape growing areas of the world. Climatic conditions in India are favorable for high production of table and wine grapes, and thus also for incidence of variety of pests. These include the sucking insect pests namely thrips, hoppers, mealybugs etc., and beetle pests like stem borer, stem girdler, flea beetles, chafer beetles, shot hole borer and several lepidopteron, mites, nematodes and vertebrate pests. Pests of grapes in other countries relevant to Indian conditions are also dealt herewith since they may get introduced in India in future. Up to date information on biology, damage, seasonal development, management practices of the pests are covered in this book. Some of the pest management practices followed in other countries are also given, which will be useful to Indian conditions. Pesticide residue is a serious problem both for export and internal market in grapes. Guideline for pesticide residue management in grapes is also given in this book. The authors have tried to accommodate almost all the important information generated on the grape pests up to 2012. A complete list of grape pests (except disease) occurring in different grape growing regions of the world is also covered in this book which will be ready reckoner for the grape workers. The authors sincerely hope that this book will provide useful information to many entomologists, students working on grapes and the grape growers in the country. It is a pleasure to thank all those people who gave help, suggestions and encouragement in the preparation of our book “The Grape Entomology”.

Perspectives in Inflammation Biology

by Ena Ray Banerjee

“Perspectives in Inflammation Biology” outlines detailed studies using preclinical murine models in Inflammation. The book is meant for academicians, industry persons, research scholars and students alike. The detailed perspective for a beginner and the exhaustive methodologies and analyses outlined, for the veteran researcher, makes this book a unique link between someone who is thinking of embarking on a study of inflammation and one who is delving deep into this area of specialization. The book deals with asthma and allergy as specific disease areas of inflammation of the lung, aseptic peritonitis as a disease of systemic inflammation and details how each role player in its pathophysiology has a unique niche of activity. Data acquisition, sequentiality and analyses in context demonstrate how each role player is validated systematically to become a target for drug discovery. Methods and models used in the course of my work and their relevance will demonstrate to the researcher how a study can be developed from an idea. Further into a researcher’s ongoing work, this book is meant to stimulate new questions and pave ways for better dissection of a phenomenon. The highlights of this book are the detailed tables tabulating sub species of immune cells, their inflammatory recruitment indices, their translation into tissue-to-tissue traffic of the inflammatory stimulus and the delicate interplay of resident structural cells, cells recruited from circulation, their feedback poiesis in bone marrow, their instruction in the lymphoid organs and tissues as well as the non-cellular mediators synthesized from corresponding genetic instruction. The book shall definitely help students and researchers how a disease can be simplified from its complex ramifications and network of implications and put back into perspective and the whole thing falls into place without an intimate understanding of the mechanism and the compelling circumstances that causes a disease, a drug hunter cannot hope to begin her quest. To find the “Achilles’ heel” and effectively neutralize the enemy!

Parasitic Zoonoses

by B.B.Singh Dhaliwal Prayag Dutt Juyal

The book “Parasitic Zoonoses” emphasizes a veterinary and public health perspective of zoonotic parasites. This book is suitable for higher undergraduate and graduate students of zoonoses and public health, veterinary parasitology, parasite epidemiology; public health workers; public health veterinarians; field veterinarians, medical professionals and all others interested in the subject. More than 15 protozoa and 50 other parasitic diseases are zoonotic in nature and all these diseases have been discussed in detail. The first chapter is concerned with classification of zoonotic parasites, food borne, vector borne and occupation related zoonotic parasites. The remaining chapters cover etiology, epidemiology, life cycle, transmission, clinical signs, diagnosis, prevention and control of zoonotic parasites. The text is illustrated with a large number of coloured figures. An alphabetical bibliography for every disease has also been included so that readers have access to further information.

Biological Control of Insect Pests Using Egg Parasitoids

by S. Sithanantham, Chandish R. Ballal, S. K. Jalali and N. Bakthavatsalam

The theme of the book is highly relevant to the current emphasis on environment conservation, with focus on native biodiversity conservation in agro-ecosystems. The current impetus being given to organic farming and export oriented agri-hortculture in the country calls for access to relevant scientific knowledge base among the stakeholders. Research on biological pest control is more than a century old in India. Egg parasitoids, which are mainly tiny wasps, led by the family Trichogrammatidae, are the most widely utilized natural enemies for biological control globally. Over thirty countries are using these bioagents to protect over 10 million hectares of agricultural and forestry crops from many important insect pests. The book comprises 18 chapters, which are arranged in continuum, commencing with basic aspects of knowledge and ending in their utilization targets. The chapters cover broadly four areas: bio-diversity and natural occurrence of egg parasitoids, behaviour and adaptation of egg parasitoids, mass production and safe use of egg parasitoids and utilisation of egg parasitoids in different crop ecosystems. Some of the chapters cater to the needs of discipline-wise update on the current R&D scenario-like insect taxonomy, biotechnology, mass-production and quality control of the target organisms - egg-parasitoids, which are useful for laboratory scientists/researchers. There are also chapters devoted to knowledge status and scope for utilization of egg parasitoids in different target crops, which cater to requirements of field entomologists and extensionists for use in their tasks of guiding farmers/local guides. The book is different in approach, method, structure and content and ensures holistic coverage of the topic. The chapters are written by active and experienced workers in different crops and aspects and co-edited by four very experienced experts who have over three decades R&D experience in the subject. All the authors have uniformly focussed on comprehensive literature study and critical identification of knowledge gaps for future R&D, thus the book is novel in outlook, up-to-date in content and comprehensive in coverage of themes. This book will be useful for supplementary reading for MSc Agriculture and PhD Agriculture students, besides MSc/PhD research students in Zoology/Environmental Biology, who are specialising in Entomology. It would also serve as a very useful reference book for researchers worldwide, though focus is also there on Indian work. It addresses the special information needs of students and faculty, besides practitioners and extensionists in the Australasia and Africa regions and thus not limited to the R&D knowledge generated in developed countries.

Heat Stress and Animal Productivity

by Anjali Aggarwal Ramesh Upadhyay

Dr. Anjali Aggarwal is working as a Senior Scientist at National Dairy Research Institute, Karnal (India). She holds a PhD degree in Animal Physiology and is involved in research and teaching at post-graduate level. Her area of research work is stress and environmental physiology. She has more than 50 publications, two technical bulletins, four manuals and many book chapters to her credit. She has successfully guided many post-graduate and PhD students. Her major research accomplishments are on microclimatic modification for alleviation of heat and cold stress, mist and fan cooling systems for cows and buffaloes, and use of wallowing tank in buffaloes. Her work involves the use of technology of supplementing micronutrients during dry period and early lactation to crossbred and indigenous cows for alleviating metabolic and oxidative stress and improved health and productivity. Studies are also done in her lab on partitioning of heat loss from skin and pulmonary system of cattle and buffaloes as a result of exercise or exposure to heat stress. Dr. R.C. Upadhyay is working as Head, Dairy Cattle Physiology Division at National Dairy Research Institute, Karnal (India). He graduated in Veterinary Sciences and obtained his PhD degree in Animal Physiology. His area of recent research is climate change, stress, and environmental physiology. His major research accomplishment is on climate change impact assessment of milk production and growth in livestock. His work also involves studying methane conversion and emission factors for Indian livestock and use of IPCC methodology of methane inventory of Indian livestock. Heat shock protein-70 expression studies in cattle and buffaloes are also done in his lab. Draught animal power evaluation, fatigue assessment, work-rest cycle and work limiting factors form the highlights of his work. Studies on partitioning of heat loss from skin and pulmonary system of cattle and buffaloes and electrocardiographic studies in cattle, buffalo, sheep and goat are also undertaken in his lab. He has more than 75 research papers, four books and several book chapters to his credit. Technologies developed and research done by him include methodology of methane measurement: open and closed circuit for cattle and buffaloes; inventory of methane emission from livestock using IPCC methodology; livestock stress index: thermal stress measurement based on physiological functions; and draught power evaluation system and large animal treadmill system. He received training in Radio-nuclides in medicine at Australian School of Nuclear Technology, Lucas heights, NSW, Australia in 1985 and Use of radioisotopes in cardiovascular investigations at CSIRO, Prospect, NSW, Australia, during 1985-86. He has guided several post-graduate and PhD students. He is recipient of Hari Om Ashram Award-1990 (ICAR) for outstanding research in animal sciences.

Mosquito Vectors of Japanese Encephalitis Virus from Northern India: Role of BPD hop cage method (SpringerBriefs in Animal Sciences)

by Bina Pani Das

Japanese Encephalitis (JE), a mosquito borne disease, is the leading cause of viral encephalitis in 14 Asian countries due to its epidemic potential, high case fatality rate and increased possibility of lifelong disability in patients who recover from this dreadful disease. In spite of seriousness of the disease, still only few books are available for ready reference. Hence, this book will be useful for students, entomologists, paramedical staff and vector control managers in public health. The objective of the book is to disseminate the knowledge gained by the author from ecological studies on JE vectors undertaken in 2 endemic and 2 non endemic areas of Northern India over a period of last 15 years (1998-2012) of research in the field of ecology of mosquito vectors of JE virus initially at National Institute of Communicable Diseases (Ministry of Health & Family Welfare, Government of India), Delhi and later at Jamia Millia Islamia, a Central University, Delhi, to anyone who wishes to curtail death of children due to this dreaded disease. Of the thousand suspected JE deaths in India annually, more than 75% is contributed by Northern India wherein disease transmission failed to be explained based on entomological evidence due to inadequate mosquito surveillance tool used in determining JE vector density. In order to overcome the above problem, Dr Bina Pani Das, the author of this book, developed “BPD hop cage method”, a simple, cost effective, and operationally feasible surveillance tool specially designed to capture predominantly day resting adult Cx. tritaeniorhynchus mosquitoes, the principal JE vector species in the country from land and aquatic vegetation.

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