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Jahre der Entwicklung der Neurochirurgie in Deutschland: Erinnerungen, Wilhelm Tönnis, 1898–1978

Wilhelm Tönnis hatte am Ende seines Lebens vor, die Geschichte der deutschen Neurochirurgie an seinem Le­ bensbericht darzustellen. Er hat jedoch leider nur einen Torso, d. h. einzelne Kapitel hinterlassen können. Zu früh nahm ihm der Tod die Feder aus der Hand. Seine Freunde hielten es aber für wichtig, diese Berichte für die deutsche Neurochirurgie zu erhalten. Als Dr. Dr.h.c. mult. Heinz Götze sich bereit erklärt hatte, diesen Bericht in überarbeiteter Form im Springer-Verlag drucken zu lassen, habe ich diese Aufgabe übernommen. Mir schien es aber wichtig, zwischen den oft nur bruchstück­ haften Erinnerungen kurze Sachdarstellungen zu setzen, die den geschichtlichen Zusammenhang besser verständlich machen, in dem diese Einzelstücke stehen. Sie sind durch ein "Z" und Kursiv-Druck gekennzeichnet. Ich glaubte, diese Aufgabe übernehmen zu können, da ich einen großen Teil meines Lebens mit Wilhelm Tönnis - oder in seiner Nähe - verbracht habe. Ich hoffe, daß das - wenn auch bruchstückhafte - Ergebnis die Geschichte der deutschen Neurochirurgie lebendig erhalten kann. Ich erwähne hier dankbar die Hilfe durch Frau Herma Tönnis. An vielen Stellen habe ich Arbeiten aus der Literatur zitiert, damit bestimmte Angaben oder Anschauungen er­ weitert im Original nachgelesen werden können. Sicher ist dies keine vollständige Geschichte der deut­ schen Neurochirurgie geworden, doch hoffe ich, daß das Wirken von Wilhelm Tönnis für das Werden der deutschen V Neurochirurgie - deren Schöpfer er ja letzten Endes wa- im Gedächtnis der folgenden Generationen erhalten bleibt.

Zerebrale Gefäßkrankheiten im Alter: Diagnostik, Therapie, Rehabilitation

Atlas of the Histology of Brain Tumors / Histologischer Atlas der Hirntumoren / Atlas d’histologie des tumeurs cérébrales / Atlas histológico de los tumores cerebrales / Гистологический атлас опухолей мозга человека: (pdf)

The NPY Family of Peptides in Immune Disorders, Inflammation, Angiogenesis, and Cancer (Progress in Inflammation Research)

Recent research indicates that the immune system and inflammatory reactions are governed and regulated by powerful neuronal mediators derived from the central and peripheral nervous system. The NPY family of peptides is a diverse group of neuropeptides that acts via multiple receptors, Y1-Y5, which are widespread not only in neurons but also in a variety of non-neural and immune cells. These peptides have been known as important regulators of many essential systems, such as blood pressure and cardiac function, food consumption and energy homeostasis. However, in recent years, they have also become recognized for their role as potent modulators of cell growth and immune functions with broad implications in chronic inflammatory diseases, cancer and angiogenesis.In this book, experts in the field analyze recent evidence supporting the role of NPY family of peptides in regulation of the immune/inflammatory system with special reference to its medical and therapeutic implications.

NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics (Experientia Supplementum #95)

The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists which are in clinical development for obesity while NPY Y1 receptors are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders are also actively pursued. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders, written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine.

Vorm en beweging: Leerboek van het bewegingsapparaat van de mens

Vorm en beweging is hét leerboek over het bewegingsapparaat voor medische en paramedische studenten. Dit fraaie boek valt op door zijn helder geschreven tekst en de grote hoeveelheid anatomische tekeningen. Niet voor niets wordt Vorm en beweging al bijna vijftig jaar door vele opleidingen gebruikt als hét studieboek op het gebied van de functionele anatomie van het menselijk bewegingsapparaat.Voor dit boek is een website ontwikkeld die exclusief toegang geeft tot de complete tekst, ondersteunende video’s, fotomateriaal en diagnostische toetsen.In deze veertiende druk zijn 7 illustraties toegevoegd of gewijzigd. Daarnaast zijn teksten inhoudelijk aangepast. Aan het hoofdstuk “Stand en beweging” is bij de paragrafen “Analyse van het gaan” en “Analyse van het hardlopen” het onderwerp “de plantaire druk” toegevoegd.Drs .A. Zuidgeest heeft bewegingswetenschappen gestudeerd aan de Vrije Universiteit Amsterdam en werkte als docent Anatomie en Kinesiologie aan de Hogeschool van Amsterdam en de Hogeschool voor Fysiotherapie Thim van der Laan.

Ik bepaal: Stap voor stap naar mijn juiste gewicht

Wil je meer dan 5 kilo afvallen en zoek je naar een manier om je gewicht blijvend omlaag te brengen? Dan geef je jezelf met dit boek de beste kans van slagen! De meeste afslankboeken bepalen voor jou wat de beste manier is om af te vallen. Natuurlijk hebben de schrijvers van die boeken veel kennis en ervaring in huis. Daarom lukt het ook wel zon dieet een periode vol te houden. Toch val je vaak na een tijdje weer terug in je eigen, oude gewoonten. En stijgt daarbij je gewicht helaas weer. `Maar dit is toch ook een afslankboek, dus wat is dan het verschil?' Het verschil met andere dieetboeken is dat dit boek ervan uit gaat dat lijnen de beste kans van slagen heeft als jijzelf bepaalt wat je verandert en wanneer je dit doet. En dat je dit in kleine stappen doet om blijvend succes te garanderen. Het boek bevat vele mogelijke factoren die een rol spelen bij overgewicht. De opbouw van het boek is zodanig dat jijzelf steeds bepaalt welk onderdeel voor jou van toepassing is, óf je hieraan gaat werken en wanneer je dat doet. Het zit barstensvol duidelijke wetenschappelijke informatie, praktische tips en ervaringen van de schrijfster en lijners. Dit boek helpt jou - Je kennis te vergroten over alles wat invloed heeft op je gewicht - Uit de vele mogelijke oorzaken van overgewicht, die oorzaken te vinden die voor jou van toepassing zijn - Realistische en haalbare doelen te stellen, waardoor je jojo-en voorkomt - Uit te vinden hoe je anders wil eten en hoe je dingen anders wil doen om blijvend af te vallen - Te bepalen of het nu wel de beste tijd is om bepaalde gewoonten te veranderen - Nieuwe gewoonten vol te houden, zodat je afvalt en op gewicht blijft Met dit boek werk je stap voor stap toe naar een blijvend gezond gewicht.

Between Sea and Sky: Aerial Aquatic Locomotion in Miniature Robots (Biosystems & Biorobotics #29)

This book reports on the state of the art in the field of aerial-aquatic locomotion, focusing on the main challenges concerning the translation of this important ability from nature to synthetic systems, and describing innovative engineering solutions that have been applied in practice by the authors at the Aerial Robotics Lab of Imperial College London. After a general introduction to aerial-aquatic locomotion in nature, and a summary of the most important engineering achievements, the book introduces readers to important physical and mathematical aspects of the multimodal locomotion problem. Besides the basic physics involved in aerial-aquatic locomotion, the role of different phenomena happening in fluids, or those due to structural mechanics effects or to power provision, are presented in depth, across a large dimension range, from millimeters to hundreds of meters. In turn, a practice-oriented discussion on the obstacles and opportunities of miniaturization, for both robots and animals is carried out. This is followed by applied engineering considerations, which describe relevant hardware considerations involved in propulsion, control, communication and fabrication. Different case studies are analyzed in detail, reporting on the latest research carried out by the authors, and covering topics such as propulsive aquatic escape, the challenging mechanics of water impact, and a hybrid sailing and flying aircraft. Offering extensive and timely information on the design, construction and operation of small-scale robots, and on multimodal locomotion, this book provides researchers, students and professionals with a comprehensive and timely reference guide to the topic of aerial-aquatic locomotion, and the relevant bioinspired approaches. It is also expected to inspire future research and foster a stronger multidisciplinary discussion in the field.

Homelessness and Social Work: An Intersectional Approach (Routledge Advances in Social Work)

Drawing on intersectional theorising, Homelessness and Social Work highlights the diversities and complexities of homelessness and social work research, policy and practice. It invites social work students, practitioners, policy makers and academics to re-examine the subject by exploring how homelessness and social work are constituted through intersecting and unequal power relations. The causes of homelessness are frequently associated with individualist explanations, without examining the broader political and intersecting social inequalities that shape how social problems such as homelessness are constructed and responded to by social workers. In reflecting on factors such as Indigeneity, race, ethnicity, gender, class, age, sexuality, ability and other markers of identity the author seeks to: • construct a new intersectional framework for understanding social work and homelessness; • provide a critical analysis of social work responses to homelessness; • challenge how homelessness is represented in social work research, social policy and social work practice; and • incorporate the stories of people experiencing homelessness. The book will be of interest to undergraduate and higher research degree students in the fields of intersectionality, homelessness, sociology, public policy and social work.

Homelessness and Social Work: An Intersectional Approach (Routledge Advances in Social Work)

Drawing on intersectional theorising, Homelessness and Social Work highlights the diversities and complexities of homelessness and social work research, policy and practice. It invites social work students, practitioners, policy makers and academics to re-examine the subject by exploring how homelessness and social work are constituted through intersecting and unequal power relations. The causes of homelessness are frequently associated with individualist explanations, without examining the broader political and intersecting social inequalities that shape how social problems such as homelessness are constructed and responded to by social workers. In reflecting on factors such as Indigeneity, race, ethnicity, gender, class, age, sexuality, ability and other markers of identity the author seeks to: • construct a new intersectional framework for understanding social work and homelessness; • provide a critical analysis of social work responses to homelessness; • challenge how homelessness is represented in social work research, social policy and social work practice; and • incorporate the stories of people experiencing homelessness. The book will be of interest to undergraduate and higher research degree students in the fields of intersectionality, homelessness, sociology, public policy and social work.

Essential Travel Medicine

This 1st edition of Essential Travel Medicine provides an excellent concise introduction to the specialty of Travel Medicine. This core text will enable health care practitioners particularly those new to the clinical practice of Travel Medicine, to gain a fundamental understanding of the diverse and complex issues which can potentially affect the health of the many millions of people who undertake international travel. Jane N Zuckerman is joined by Gary W Brunette from CDC and Peter A Leggat from Australia as Editors. Leading international specialists in their fields have contributed authoritative chapters reflecting current knowledge to facilitate best clinical practice in the different aspects of travel medicine. The aim of Essential Travel Medicine is to provide a comprehensive guide to Travel Medicine as well as a fundamental knowledge base to support international undergraduate and postgraduate specialty training programmes in the discipline of Travel Medicine. The 1st edition of Essential Travel Medicine offers an indispensable resource of essential information for travel health practitioners, infectious disease specialists, occupational health specialists, public health specialists, family practitioners, pharmacists and other allied health professionals. This core text will appeal similarly to those training in Travel Medicine and to those who want a concise introduction to the subject or an ideal revision companion.

Essential Travel Medicine

This 1st edition of Essential Travel Medicine provides an excellent concise introduction to the specialty of Travel Medicine. This core text will enable health care practitioners particularly those new to the clinical practice of Travel Medicine, to gain a fundamental understanding of the diverse and complex issues which can potentially affect the health of the many millions of people who undertake international travel. Jane N Zuckerman is joined by Gary W Brunette from CDC and Peter A Leggat from Australia as Editors. Leading international specialists in their fields have contributed authoritative chapters reflecting current knowledge to facilitate best clinical practice in the different aspects of travel medicine. The aim of Essential Travel Medicine is to provide a comprehensive guide to Travel Medicine as well as a fundamental knowledge base to support international undergraduate and postgraduate specialty training programmes in the discipline of Travel Medicine. The 1st edition of Essential Travel Medicine offers an indispensable resource of essential information for travel health practitioners, infectious disease specialists, occupational health specialists, public health specialists, family practitioners, pharmacists and other allied health professionals. This core text will appeal similarly to those training in Travel Medicine and to those who want a concise introduction to the subject or an ideal revision companion.

Principles and Practice of Travel Medicine

This second edition of Principles and Practice of Travel Medicine has been extensively updated to provide a comprehensive description of travel medicine and is an invaluable reference resource to support the clinical practice of travel medicine. This new edition covers the many recent advances in the field, including the development of new and combined vaccines; malaria prophylaxis; emerging new infections; new hazards resulting from travel to long haul destinations; health tourism; and population movements. The chapter on vaccine-preventable diseases includes new developments in licensed vaccines, as well as continent-based recommendations for their administration. There are chapters on the travel health management of high risk travellers, including the diabetic traveller, the immuno-compromised, those with cardiovascular, renal, neurological, gastrointestinal, malignant and other disorders, psychological and psychiatric illnesses, pregnant women, children and the elderly. With increasing numbers of ever more adventurous travellers, there is discussion of travel medicine within extreme environments, whilst the chapter on space tourism may well be considered the future in travel medicine. Principles and Practice of Travel Medicine is an invaluable resource for health care professionals providing advice and clinical care to the traveller.

Principles and Practice of Travel Medicine

This second edition of Principles and Practice of Travel Medicine has been extensively updated to provide a comprehensive description of travel medicine and is an invaluable reference resource to support the clinical practice of travel medicine. This new edition covers the many recent advances in the field, including the development of new and combined vaccines; malaria prophylaxis; emerging new infections; new hazards resulting from travel to long haul destinations; health tourism; and population movements. The chapter on vaccine-preventable diseases includes new developments in licensed vaccines, as well as continent-based recommendations for their administration. There are chapters on the travel health management of high risk travellers, including the diabetic traveller, the immuno-compromised, those with cardiovascular, renal, neurological, gastrointestinal, malignant and other disorders, psychological and psychiatric illnesses, pregnant women, children and the elderly. With increasing numbers of ever more adventurous travellers, there is discussion of travel medicine within extreme environments, whilst the chapter on space tourism may well be considered the future in travel medicine. Principles and Practice of Travel Medicine is an invaluable resource for health care professionals providing advice and clinical care to the traveller.

A Shot to Save the World: The Remarkable Race and Ground-Breaking Science Behind the Covid-19 Vaccines

This is the definitive account of the global effort to develop a vaccine for Covid-19, charting the failure and success of every major vaccine in use.When the coronavirus pandemic hit, many of the world's biggest drug and vaccine makers were slow to react or couldn't muster an effective response. It was up to a small group of unlikely and untested scientists and executives to save civilization; a French businessman dismissed by many as a fabulist, a Turkish immigrant with little virus experience, a quirky American Midwesterner obsessed with insect cells, a Boston scientist employing questionable techniques, a British scientist despised by his peers. They scrambled to turn their life's work into life-saving vaccines in a matter of months, each gunning to make the big breakthrough - and to beat each other for the glory that a vaccine guaranteed.A number-one New York Times bestselling author and award-winning Wall Street Journal investigative journalist, Zuckerman takes us inside the top-secret laboratories, corporate clashes and high-stakes government negotiations that led to effective vaccines development and roll out. Meticulously reported and endlessly gripping, this is a dazzling, blow-by-blow chronicle of the most consequential scientific breakthrough of our time. It's a story of courage, genius and heroism, optimism. It's also a tale of heated rivalries, unbridled ambitions, crippling insecurities and unexpected drama.A Shot to Save the World is the story of how science saved the world.

Hepatitis Viruses of Man

Hepatitis Viruses of Man covers the advances and developments in the study of viral hepatitis. The book discusses the history, epidemiology, and clinical features of viral hepatitis; the nomenclature and morphology of hepatitis viruses and their antigens; and the pathology of the liver in acute viral hepatitis. The text also describes the biochemical and biophysical properties of hepatitis B surface antigen; the nature and immunopathogenesis of hepatitis B; and the laboratory tests for hepatitis B surface antigen and antibody and hepatitis B core antigen and antibody. The carrier state; maternal transmission of hepatitis B and neonatal infection; and Hepatitis B virus and primary liver cancer are also considered. The book further tackles the laboratory tests for hepatitis A and the nature of the virus; immunization against hepatitis; and interferon and antiviral therapy in chronic hepatitis B infection. Microbiologists, pathologists, and medical doctors will find the book useful.

Principles and Practice of Clinical Virology

The knowledge and practice of clinical virology continues to expand. This new fifth edition has thirty-six comprehensive chapters, each of which has been extensively revised or rewritten, with the addition of new colour plates. This updated version takes into account knowledge accumulated in molecular biology with its applications for laboratory diagnosis, immunisation and antiviral chemotherapy. Each chapter highlights the clinical features and epidemiological patterns of infection. Similarly, in response to the global concern of the threat posed by new viruses, a new chapter on Emerging Infections is included. There is also new material on Hospital Acquired Infections, including some advice relating to SARS, that will be of benefit to those dealing with the day-to-day management of patients in hospital.

Principles and Practice of Clinical Virology

Principles and Practice of Clinical Virology is the bible for all working in the field of clinical virology – from the trainee to the expert because there’s always something new to learn! As before, the book provides a detailed account of the diagnosis and treatment of virus infections, with a stronger emphasis on clinical expertise and management. Each chapter deals with a single virus or group or viruses and is written by leading international experts in the field. What’s new in this edition … Showcases the wealth of new knowledge acquired on virus infections and reflects the discovery of newly recognized emerging infections, the improvement or development of new vaccines, and an increasing repertoire of antiviral agents for treatment All chapters have been thoroughly revised and there are a number of new contributors, joining the cadre of internationally-recognized experts Includes a new chapter on vaccinology covering the principles relating to the development and use of vaccines generally, which complements the specific vaccines described in the other chapters The two chapters on nosocomial infections have been enlarged and will be particularly useful for those having to advise on the management of hospital-acquired infections Emphasizes the rapid accumulation of new information in such fields as retroviruses, particularly HIV, SARS, hepatitis C and influenza, including avian influenza

Reflex Control of the Circulation

Reflex Control of the Circulation presents an interdisciplinary discussion of concepts in the reflex control of circulation. This volume describes aspects of autonomic receptor physiology, central pathways of reflex control, the electrophysiology of cardiovascular afferents, the interaction between reflexes, the autonomic control of regional blood flows, the autonomic control of fluid and electrolyte balance, and neurohumoral control of the circulation through normal and pathological states (e.g., hypertension, congestive heart failure). In addition, the regulation of regional blood flow during exercise and developmental aspects of reflex control are examined. Any researcher interested in the autonomic system and its role in circulation will find this book fascinating reading.

Reflex Control of the Circulation

Reflex Control of the Circulation presents an interdisciplinary discussion of concepts in the reflex control of circulation. This volume describes aspects of autonomic receptor physiology, central pathways of reflex control, the electrophysiology of cardiovascular afferents, the interaction between reflexes, the autonomic control of regional blood flows, the autonomic control of fluid and electrolyte balance, and neurohumoral control of the circulation through normal and pathological states (e.g., hypertension, congestive heart failure). In addition, the regulation of regional blood flow during exercise and developmental aspects of reflex control are examined. Any researcher interested in the autonomic system and its role in circulation will find this book fascinating reading.

Recent Developments in Prophylactic Immunization (Immunology and Medicine #12)

It has been said that "never in the history of human progress has a better and cheaper method of preventing illness been developed than immunization". This is well illustrated by the WHO Expanded Programme on Immunization (EPI) which in developing countries is now preventing nearly a million deaths annually from measles, pertussis and neonatal tetanus, and for which there is a commitment by the WHO and UNICEF to protect all children by immunization by the end of the decade. This enormous undertaking will be facilitated by the rapid advances in molecular biology and recombinant DNA technology, in the understanding of immunological mechanisms and by the production and application of monoclonal antibodies so that the structure and location of important antigenic determinants or epitopes can be determined. Chemical synthesis of oligopeptides has been simplified, and computer programmes and X-ray crystallography provide the tools for the determination of three-dimensional structure of proteins, so that the structure and location of important antigenic determinants or epitopes can be predicted. These techniques have opened the way to the improvement of existing vaccines and to the development and production of new vaccines against infections for which vaccines are not available. New vaccines under development include vaccines against hepatitis B, hepatitis A, malaria, vaccines for typhoid, cholera, rota virus infection and other diarrhoeal diseases, leprosy, rabies, the acquired immune deficiency syndrome (AIDS), rubella, EB virus, schistosomiasis and other infections. These recent developments are discussed in the volume by internationally recognized experts assembled from several countries.

Resources and Society: A Systems Ecology Study of the Island of Gotland, Sweden (Ecological Studies #56)

Although this book is about a specific area of the world (i.e., Gotland, Sweden), the interdisciplinary nature of the study, with regard to resources, environment, and society, makes it of interest to a number of fields. We have tried to make this book readable for a wide variety of interested parties including systems ecologists, environmental scientists, resource economists, geographers, regional planners, and regional scientists, as well as those interested in Nordic conditions. Since this project was part of UNESCO's Man and the Biosphere (MAB) pro­ gram, this book should be of general interest to the international community. This book is certainly not a textbook, but we see it as being useful for courses in regional analysis with plenty of examples for illustrating analysis and models related to energy, environment, and economics, or to the general field of systems ecology. An instructor could, of course, supplement the material on systems and models with other sources. We hope this small book will serve as a helpful example of the analysis of the complex interdisciplinary problems associated with resources and society. In Chapter 1, we present a brief introduction to the Gotland study as well as to some of the concepts and theories that have guided our investigations.

Cleaning Up: How Hospital Outsourcing Is Hurting Workers and Endangering Patients (The Culture and Politics of Health Care Work)

To cut costs and maximize profits, hospitals in the United States and many other countries are outsourcing such tasks as cleaning and food preparation to private contractors. In Cleaning Up, the first book to examine this transformation in the healthcare industry, Dan Zuberi looks at the consequences of outsourcing from two perspectives: its impact on patient safety and its role in increasing socioeconomic inequality. Drawing on years of field research in Vancouver, Canada as well as data from hospitals in the U.S. and Europe, he argues that outsourcing has been disastrous for the cleanliness of hospitals—leading to an increased risk of hospital-acquired infections, a leading cause of severe illness and death—as well as for the effective delivery of other hospital services and the workers themselves. Zuberi’s interviews with the low-wage workers who keep hospitals running uncover claims of exposure to near-constant risk of injury and illness. Many report serious concerns about the quality of the work due to understaffing, high turnover, poor training and experience, inadequate cleaning supplies, and on-the-job injuries. Zuberi also presents policy recommendations for improving patient safety by reducing the risk of hospital-acquired infection and ameliorating the work conditions and quality of life of hospital support workers. He makes the case that hospital outsourcing exemplifies the trend towards "low-road" service-sector jobs that threatens to undermine society’s social health, as well as the physical health and well-being of patients in health care settings globally.

Corneal Surgery: Essential Techniques

This book is an informative and comprehensive guide to the essential techniques currently employed in corneal surgery. It focuses in particular on two principal areas: the treatment of corneal disorders by means of different forms of corneal transplantation and the use of the Excimer laser to treat refractive disorders. In order to facilitate learning and later deployment of the techniques a multimedia approach is used. Surgical steps are described clearly within the book and can then be observed in detail on the accompanying high-quality DVD. A further feature is the inclusion of a chapter devoted to wet lab training, which presents practical preparatory exercises. This book will be of special value as a handy reference for ophthalmologists who are just embarking upon their surgical training. However, it will also be informative for trained eye surgeons, who will be able to compare their own practice with the presented procedures and to assimilate the latest techniques.

Kataraktchirurgie

Die Augenerkrankung „Grauer Star" betrifft mit zunehmendem Lebensalter fast jeden Menschen. Der Fachbegriff „Katarakt" (Wasserfall) beschreibt dabei die Sicht des Patienten, der wie durch einen Nebelschleier sieht. Das Buch bietet die optimale Begleitung beim Aneignen und Vertiefen der operativen Fertigkeiten für die Kataraktoperation. Kompakte Texte und 200 klare Schemazeichnungen illustrieren alle wichtigen Schritte. Die beigefügte DVD zeigt Operationstechniken und typische Komplikationen in bewegten Bildern mit Audiokommentar.