- Table View
- List View
Multicomponent Reactions: Synthesis of Bioactive Heterocycles
by K. L. Ameta Anshu DandiaThis timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.
Nanocatalysis: Synthesis of Bioactive Heterocycles
by Keshav Lalit AmetaThe field of nanocatalysis is undergoing rapid development. Nanocatalysis can help in designing catalysts with excellent activity, greater selectivity, and high stability. Their properties can easily be tuned by tailoring the size, shape, and morphology of the particular nanomaterial. Exhibiting both homogeneous and heterogeneous catalytic properties, nanocatalysts allow for rapid and selective chemical transformations, with the benefits of excellent product yield and ease of catalyst separation and recovery. Nanocatalysis: Synthesis of Bioactive Heterocycles reviews the catalytic performance and the synthesis and characterization of nanocatalysts, examining the current state of the art and pointing the way towards new avenues of research specially synthesis of bioactive heterocycles. Top researchers summarize synthetic methodologies for the synthesis of bioactive heterocycles using a nanocatalytic framework. The catalytic performance and the synthesis and characterization of nanocatalysts are reviewed. State of the art methods and new and emerging applications of nanocatalysts in the synthesis of biologically active heterocycles are detailed. Additional features include: Focuses on designing and synthesizing nanocatalysts specifically for the synthesis of different bioactive heterocycles. Demonstrates how nanocatalysis can produce catalysts with excellent activity, greater selectivity, and high stability. Explores tuning catalysts properties by tailoring the size, shape, and morphology of a nanomaterial. Offers the reader insights into the field of nanoscience via nanocatalysis. Nanocatalysis: Synthesis of Bioactive Heterocycles is a must read for researchers in organic chemistry, medicinal chemistry and biochemistry.
Nanocatalysis: Synthesis of Bioactive Heterocycles
by Keshav Lalit Ameta Ravi KantThe field of nanocatalysis is undergoing rapid development. Nanocatalysis can help in designing catalysts with excellent activity, greater selectivity, and high stability. Their properties can easily be tuned by tailoring the size, shape, and morphology of the particular nanomaterial. Exhibiting both homogeneous and heterogeneous catalytic properties, nanocatalysts allow for rapid and selective chemical transformations, with the benefits of excellent product yield and ease of catalyst separation and recovery. Nanocatalysis: Synthesis of Bioactive Heterocycles reviews the catalytic performance and the synthesis and characterization of nanocatalysts, examining the current state of the art and pointing the way towards new avenues of research specially synthesis of bioactive heterocycles. Top researchers summarize synthetic methodologies for the synthesis of bioactive heterocycles using a nanocatalytic framework. The catalytic performance and the synthesis and characterization of nanocatalysts are reviewed. State of the art methods and new and emerging applications of nanocatalysts in the synthesis of biologically active heterocycles are detailed. Additional features include: Focuses on designing and synthesizing nanocatalysts specifically for the synthesis of different bioactive heterocycles. Demonstrates how nanocatalysis can produce catalysts with excellent activity, greater selectivity, and high stability. Explores tuning catalysts properties by tailoring the size, shape, and morphology of a nanomaterial. Offers the reader insights into the field of nanoscience via nanocatalysis. Nanocatalysis: Synthesis of Bioactive Heterocycles is a must read for researchers in organic chemistry, medicinal chemistry and biochemistry.
Heterogeneous Catalysis: A Versatile Tool for the Synthesis of Bioactive Heterocycles
by K.L. Ameta Ph.D. Andrea PenoniFor more than a century, bioactive heterocycles have formed one of the largest areas of research in organic chemistry. They are important from a biological and industrial point of view as well as to the understanding of life processes and efforts to improve the quality of life. Heterogeneous Catalysis: A Versatile Tool for the Synthesis of Bioactiv
Periparturient Diseases of Dairy Cows: A Systems Biology Approach
by Burim N. AmetajThis book summarizes the results achieved so far by application of various biological systems (including genomics, transcriptomics, proteomics, and metabolomics) involved in the pathomechanisms and early diagnosis of periparturient diseases as specific biomarkers of disease in cattle. These emerging technologies help to extensively enhance our understanding of the etiology and pathogenesis of periparturient diseases of transition dairy cows. The book includes a chapter dedicated to ‘omics’ sciences and one that discusses the myths established in animal and veterinary sciences in recent decades and emerging, new paradigms. The diseases discussed include metritis, mastitis, laminitis, ketosis, rumen acidosis, periparturient immunosuppression, gastrointestinal microbiota and their involvement in disease, infertility, fatty liver, milk fever, and retained placenta. This book is intended for academics, veterinarians, animal nutritionists, researchers, and graduate students working in the field of ‘omics sciences’ with a special interest in dairy cattle health.
Benign Prostatic Hyperplasia: Innovations in Management
by F. Ameye K. Anson M. A. Astrahan Luc Baert K. H. Bichler S. D. Boyd L. W. Brady R. C. Bruskewitz P. Dal Cin P. S. Debicki M. Devonec C. M. Dixon J. P. Fendler E. Hoeben P. Joubert J. Keit H. Lepor W. Mattauch G. B. Mieszkalski R. H. Oyen P. Perrin Zbigniew Petrovich M. C. Pike M. Riehmann E. Shapiro B. Stawarz W. L. Strohmaier S. Szmigielski G. Ursin H. Van Berghe H. Vandeursen H. Van Poppel G. Verhoeven G. WatsonThe past 15 years have witnessed a marked increase in attempts to identify safe and effective treatment alternatives to prostatectomy. This book is a review of the current therapeutic efforts in the management of patients with benign prostatic hyperplasia. It is presented by a group of highly regarded basic and clinical scientists with a major interest in prostatic diseases.The information provided in this book is aimed at a wide audience including private practice and academic urologists, research fellows and doctors in postgraduate training, and basic scientists interested in prostatic pathology.
Myocardial Viability (Developments in Cardiovascular Medicine #226)
by Ami E. Iskandrian and Ernst E. van Der WallAMI E. ISKANDRIAN & ERNST E. VAN DER WALL The first edition of this book was published in 1994. Since then important advances have occurred in the field of myocardial viability. This, coupled with increasing interest by the scientific community in the broader issues of its relevance to patient care, suggested to us the need to write the second edition. We are most fortunate to have the help of a distinguished group of experts who have helped shape the field; we appreciate their commitments and contributions. Almost all chapters have been radically modified. Chapter 1 deals with pathophysiology of myocardial hibernation and stunning; Chapter 2 with apoptosis; Chapter 3 with the role of positron emission tomography; Chapters 4 and 5 with the role of single photon emission computed tomography with thallium-201 and technetium agents, respectively; Chapter 6 with the role of SPECT fatty acid imaging; Chapter 7 with the role of SPECT FDG imaging; Chapter 8 with the role of cardiac catheterization angiography; Chapter 9 with the role of echocardiography; Chapter 10 with the role of magnetic resonance imaging; and Chapter 11 with clinical applications. Finally, Chapter 12 provides a short summary.
Nuclear Cardiac Imaging: Principles and Applications
by Ami E. Iskandrian and Fadi G. HageNuclear cardiac imaging refers to cardiac radiological diagnostic techniques performed with the aid of radiopharmaceuticals, which are perfused into the myocardium as markers. These imaging studies provide a wide range of information about the heart, including the contractility of the heart, the amount of blood supply to the heart and whether parts of the heart muscle are alive or dead. This is essential information for cardiologists, and nuclear imaging has become an increasingly important part of the cardiologist's armamentarium. Chapters in Nuclear Cardiac Imaging cover historical, technical and physiological considerations, diagnosis and prognosis, conditions other than Coronary Artery Disease (CAD), advanced cardiac imaging, and challenges and opportunities. New to the sixth edition are key point summaries at the start of each chapter, clinical cases with videos, and a question and answer chapter on practical issues. This volume is ideal for nuclear cardiologists in training and nuclear clinicians alike who are searching for quick answers to important clinical and technical questions.
Nuclear Cardiac Imaging Companion Atlas
by Ami E. Iskandrian and Fadi G. HageA companion to the 6th edition of Nuclear Cardiac Imaging, this text offers readers additional case examples and figures not included in the related textbook as well as a concise option for readers seeking a case book for quick review for examination preparation or assistance with image interpretation. Rather than focusing on theoretical explanations, the atlas provides high-yield, rapid imaging support with a particular emphasis on cases with angiography, echocardiography, and other imaging correlations. With a variety of cases and multiple-choice self-assessment questions along with a comprehensive multiple-choice exam to be taken upon completion of the text, the Companion Atlas will solidify readers' knowledge and ranges in levels of difficulty, including those intended to challenge even the most expert reader.
Multifaceted Protocols in Biotechnology, Volume 2
by Azura AmidThis contributed volume, “Multifaceted Protocols in Biotechnology, Volume 2”, consists of multidisciplinary methods and techniques commonly used in biotechnology studies. There are two sections covered in this book – Ionic Liquid Related Techniques & Evergreen Biotechnology Techniques. A brief introduction supports each protocol to allow easy learning and implementation. The first section consists of three chapters covering studies in modern biotechnology focusing on the role of ionic liquid techniques in extracting secondary metabolites, enzyme stabilization and biomass processing. The second section covers evergreen methodologies. It comprises five chapters covering topics on microcarrier technology for cell culture; Polymerase Chain Reaction for non-halal sources detection in food; ELISA for biomarker identification; gamma ray-induced mutagenesis for enhancing microbial fuel cells; and the effect of temperature on antibacterial activity of Carica papaya seed extract. This book will be useful to graduate students, researchers, academics, and industry practitioners working in the area of biotechnology
Recombinant Enzymes - From Basic Science to Commercialization
by Azura AmidThis edited work presents studies that clarify the basics of producing recombinant enzymes that finally lead to commercialization. It enables researchers to see what is crucial to the commercialization process, from examining the cloning method, using analytical techniques such as calculating the total protein content and enzyme activity, through considering upstream and downstream processes, to the final product.Readers will discover the importance of the cloning method as it influences the upstream and downstream processes and determines the level of success of the recombinant enzyme commercialization processes. We see that the two main factors that are particularly sensitive during the cloning process are the vector and the host.A discussion of analytical techniques is presented followed by studies on important stages during the upstream processes including the process of optimizing the media to get results and high enzyme activity. Downstream processes such as the cell disruption technique, purification and formulation of the final product are then considered. The reader is introduced to software that helps streamline recombinant enzyme production from the upstream to downstream processes, to facilitate the process of up-scaling production.This work includes a case study as tool, to guide understanding of the commercialization process. The work is written for researchers in the field and is especially suited to those who are under pressure to embark on the tough process of commercialization.
Pharmacokinetics of Drugs (Handbook of Experimental Pharmacology #110)
by G. L. Amidon J.P.F. Bai L. P. Balant C. M. Barksdale I. A. Blair D. D. Breimer M. Chiba J. Delforge M. Eichelbaum B. L. Ferraiolo A. J. Fischman M. Gex-Fabry N. Holford J. Kantrowitz H. K. Kroemer T. M. Ludden J. M. Mayer B. Maziere C. McMartin G. Minkus M. A. Mohler G. D. Nordblom R. O'Neill K. S. Pang O. Pelkonen A. Racine-Poon R. H. Rubin J. L. Steimer B. H. Stewart H. W. Strauss B. Testa S. Vozeh P. G. Welling R. G. Wills A. YacobiA compilation of researchers' experience in the areas of bioanalysis, pharmacokinetics, and drug metabolism, to present an up-to-date and comprehensive treatise on the application of these and related technologies in drug discovery, development, and clinical use. Contents cover descriptions of analytical methods, in vitro metabolism technology and membrane transport, reappraisal of classical pharmacokinetic problems, and the time course of drug action. The book concludes with a description of PET and imaging methods in pharmacokinetics and an appendix containing a critical appraisal of computer methods and pharmacokinetic software available for PCs.
Membrane Transporters as Drug Targets (Pharmaceutical Biotechnology #12)
by Gordon L. Amidon Wolfgang SadéeBecause progress in the field of transporters has been extraordinary, this volume will focus on recent advances in our understanding of the structure, function, physiology, and molecular biology of membrane transporters. There will be an emphasis on transporters as molecular targets for drug delivery and disposition in the body.
Essential Obstetric Practice
by G.J. AmielAdvances in research, knowledge and clinical practice in all branches of medicine have been rapid over the past decades and the speed is accelerating. Thus, as we enter the 1980s the pressure on specialists is to concentrate on ever-narrowing fields of their science. For the research worker this is desirable, but the practising clinician Our patient is a whole can have no clearly defined dividing lines. individual and every aspect of her makeup, physical and psychological, must always be taken fully into account. This is of vital importance in obstetrics and gynaecology. These two closely inter woven disciplines are branches of medical science in which emergency situations are not uncommon. Thus every practitioner, doctor, mid wife and nurse needs understanding of these subjects. Although tech nology advances rapidly, many basic principles remain the same. The chapters that follow deal with these, and modern trends in clinical management are discussed. For some decades the author has been in clinical charge of a matern ity hospital some 12 miles south of Central London. The hospital is a training school for obstetricians and midwives, and the local popula tion is adequately supplied with a general practitioner service. These circumstances are of some relevance because many views expressed are based on personal experience while others are based on countless books, articles, congresses and discussion with colleagues. To every source of information I express my thanks.
Coronary Artery Diseases: Diagnostic and Therapeutic Imaging Approaches
by M. Amiel A. Maseri H. Petitier N. Vasile2 Diagnostic Use of Radiographic Methods in Coronary Disease. . . . . . . . . . . . . . . . . . . . . . . . . . 56 3 Material. . . . . . . . . . . . . . . . . . . . . . . . . 58 4 Mode of Operation . . . . . . . . . . . . . 62 5 Radiological Projections. . . . . . . . . . . . . . . . . 63 6 Monitoring of Cardiac Parameters . . . . . . . . . . . . 64 7 Pharmacological Tests . . . . . . . . . . . . . . . . 66 7. 1 Coronary Arteries . . . . . . . . . . . . . . . . . . . . . 66 7. 2 Left Ventricle. . . . . . . . . . . . . . . . . . . . . . . . 67 8 Accidents and Risks of Coronary Arteriography . . . . . 67 References . . . . . . . . . . . . . . . . . . . . . . . . . 68 III Angiographic Explorations: Normal Results . . . 71 1 Left Ventricle and Left Ventricular Function 71 1. 1 Radiological Anatomy. . . . . . . . . . . . 71 1. 2 Normal Kinetics. . . . . . . . . . . . . . . 77 1. 3 Analysis of Wall Contraction . . . . . . 78 1. 4 Volumes and Function Indexes. . . . . . . 81 2 Coronary Arteries and Veins . . . . . . . . 84 2. 1 Origin, Calibre and Preponderance of the Coronary Arteries . . . . . . . . . . . . . . . . . . . . . . . . 84 2. 2 Nomenclature and Segmentation of the Coronary Arteries . . . . . . . . . . . . . . . . . . . . . . 87 2. 3 A Reminder About the Physiology of Coronary Circulation . . . . . . . . . . . 93 2. 4 Angiographic Anatomy . . . . . . . . . . 94 2. 4. 1 Left Coronary Artery . . . . . . . . . . . 94 2. 4. 2 Right Coronary Artery. . . . . . . . . . . . . 95 2. 4. 3 Vascularization of Nodes and the Conduction System . . 96 2. 4. 4 Interconnecting Anastomoses . . . . . . . . . . . . . . . 97 2. 5 Coronary Veins . . . . . . . . . . . . . . . . . . . 97 References . . . . . . . . . . . . . . . . . . . . . . . . . 98 IV Angiographic Explorations: Congenital Anomalies of the Coronary Arteries. . . . . . . . . . . . . . . . . . . . . . . . 100 1 Anomalies of the Origin, Course and Distribution of Coronary Arteries Arising from the Aorta . . . . . . . . 100 2 Abnormal Origin of a Coronary Artery from the Pulmonary Artery . . . . . . . . . . . . . . . . . . . . . 101 3 Anomalies in the Diameter of Coronary Arteries . . . . . 104 4 Coronary Fistulae . . . . . . . . . . . 109 References . . . . . . . . . . . . . . . . . . . . . . . . . 113 VII V Angiographic Explorations: Coronary Atheroma. . . . . . . . 114 1 Left Ventricle . . . . . . . . . . . . . . . . . . . . . . . . 114 1. 1 Morphological Anomalies: Bulging and Lacuna-Like Aspects . . . . . . . . . . . . . . . . . . . . . . . . . . .
Special Topics in Information Technology (SpringerBriefs in Applied Sciences and Technology)
by Francesco AmigoniThis open access book presents outstanding doctoral dissertations in Information Technology from the Department of Electronics, Information and Bioengineering, Politecnico di Milano, Italy. Information Technology has always been highly interdisciplinary, as many aspects have to be considered in IT systems. The doctoral studies program in IT at Politecnico di Milano emphasizes this interdisciplinary nature, which is becoming more and more important in recent technological advances, in collaborative projects, and in the education of young researchers. Accordingly, the focus of advanced research is on pursuing a rigorous approach to specific research topics starting from a broad background in various areas of Information Technology, especially Computer Science and Engineering, Electronics, Systems and Control, and Telecommunications. Each year, more than 50 Ph.D.s. graduate from the program. This book gathers the outcomes of the best theses defended in 2022–23 and selected for the IT Ph.D. Award. Each of the authors provides a chapter summarizing his/her findings, including an introduction, description of methods, main achievements and future work on the topic. Hence, the book provides a cutting-edge overview of the latest research trends in Information Technology at Politecnico di Milano, presented in an easy-to-read format that will also appeal to non-specialists.
Advances in Celiac Disease: Improving Paediatric and Adult Care
by Jorge Amil-Dias Isabel PolancoThis book provides a practical overview of the treatment and management of celiac disease. It examines new data which can be merged with clinical aspects to provide a global perspective for the busy clinician. The disease represents 1% of the population and often goes unnoticed for a long time; however, this book aims to reduce the instance of misdiagnoses of symptoms by providing clear guidance in a single book, with contributions from esteemed experts in the field. Advances in Celiac Disease - Improving Paediatric and Adult Care addresses the clinical characterisation of the disease, in both paediatric and adult populations. The clinical symptoms are clearly defined as well as treatment options and follow-up. This book will be an essential resource for clinicians seeking a clear, concise resource to identifying, treating, and managing celiac disease in both adults and children.
Vascular Neurology Board Review: An Essential Study Guide
by Hardik P. Amin Joseph L. SchindlerThis concise, yet comprehensive review covers the diagnostic and treatment information needed for the vascular neurology board exam. The assembled material is easy-to-read with chapters emphasizing clinically relevant scientific principles that must be mastered by the stroke clinician. Neurology, vascular neurology and neuro-critical care residents and fellows will find this text to be an invaluable preparation guide and a succinct source to complement treatment guidelines and protocols.
Vascular Neurology Board Review: An Essential Study Guide
by Hardik P. Amin Joseph L. SchindlerThis book provides a concise review for practitioners in preparation for the Vascular Neurology Boards including the Maintenance of Certification exam. This valuable second edition is expertly written and supplemented with new treatment paradigms as well as new and updated trial results.. Beginning with a general overview on how to prepare for the exam, this practical guide emphasizes clinically relevant scientific principles that must be mastered by the stroke clinician. Subsequent chapters review acute management of ischemic and hemorrhagic stroke, specific epidemiological risk factors, stroke pathophysiology, stroke classification, and vascular neuroanatomy. This edition also reviews cardiac and hematological considerations in stroke patients, genetic stroke syndromes, vascular malformations, cognitive disorders, stroke rehabilitation, and peri-operative stroke management. Vascular Neurology Board Review, Second Edition, is not only written to act as a guide for the neurology resident and fellow, but also as a useful framework for non-neurologists.
Decision Making in Vocal Fold Paralysis: A Guide to Clinical Management
by Milan R. Amin Michael M. JohnsThis guide brings thought leaders and master clinicians together to share their wisdom and expertise regarding clinical decisions surrounding unilateral and bilateral vocal fold paralysis. Designed as a what- to-do and why as opposed to a how-to guide, the authors detail the reasoning process from work up, through intervention, to post-treatment decision making. The text is organized around decision points in the management of vocal fold paralysis such as decisions in regard to timing, intervention, implants, reinnervation, drugs, voice therapy, and post-operative care. Individual chapters focus on specific steps in the process of evaluation and treatment, explore the decisions that can and should be made, and provide answers and direction for the reader. Authors explain the issues around the decision point and use their considerable experience to offer their opinion and as well as the thought process behind it. Decision Making in Vocal Fold Paralysis will be a useful guide for practitioners that deal with vocal fold paralysis, including otolaryngologists, general surgeons, neurologists, speech language pathologists, primary care physicians, and oncologists.
Proceedings of the 5th International Conference on Neuroscience, Neurology and Psychiatry (Advances in Health Sciences Research #59)
by Mustafa M. Amin Elmeida Effendy Dina K. Sari Kiking Ritarwan Banthit Chetsawang Mirko Spiroski Zöe Bichler Uttam K. SharmaThis is an open access book.Neuroscience is an emerging branch of science that develops rapidly. It needs neurology, psychiatry, and psychology for us to understand it better. The aim of this conference is to educate and learn the current trends and research in neuroscience education. The 5th International Conference on Neuroscience, Neurology and Psychiatry (ICoNaP) 2022 is a conference held by The Faculty of Medicine of Universitas Sumatera Utara for psychiatrists, neurologists, general practitioners, and other interested specialists; the theme for this year is “Exploring the Neuroscientific Impact of Covid-19”.ICoNAP has been held annually since 2018. The conference invites both national and international speakers from many countries. Throughout these years the committee has invoted various speakers from Malaysia, Singapore, Germany, Australia, India, Thailand, the USA, France, and Malaysia. This year, we invite both national and international speakers from the United Kingdom, Japan, Australia, Singapore, and Malaysia and will be held as a virtual conference.
Patent Foramen Ovale
by Zahid Amin Jonathan M. Tobis Horst Sievert John D. CarrollThis book is the ultimate reference on patent foramen ovale (PFO), a defect in the septum of the heart estimated to be present in more than twenty percent of the adult population and a proven cause of systemic embolism. All chapters have been written by internationally recognized experts in the field and cover PFO genetics and anatomy in addition to the effect PFO can have on various different organs and its supposed involvement in several conditions and clinical syndromes such as migraine, diving incidence, platynea orthodeoxia, economy class syndrome, sleep apnea and persistent desaturations in mild right ventricular dysfunction. As PFO anatomy varies significantly between individuals, chapters have also been included on the diagnostic tools, methods and techniques for appropriate assessment, detection and characterization of PFO. Furthermore, the multitude of available closure devices and techniques for PFO closure are discussed together with current and ongoing trial data. The book concludes with guidance and instruction on establishing a successful PFO program.Patent Foramen Ovale will be an essential text for the whole adult and pediatric interventional community, general cardiologists, internists, primary care physicians, neurologists and device companies in addition to medical students, graduate students and fellows in training.
Clinical Aspects of Microdialysis (Acta Neurochirurgica Supplement #67)
by Aminadav Mendelowitsch, Helen Langemann, Beat Alessandri, Hans Landolt and Otmar GratzlMicrodialysis is a minimally invasive method which enables continuous monitoring of parameters in the extracellular space of various tissues. It has been investigated in animal models for over a decade, and many publications have provided insight into its advantages and disadvantages. However, in spite of its enormous potential for revealing metabolic processes in normal and pathological tissue, microdialysis in humans is still in its infancy. Clinical neurointensive medicine nowadays demands much more than conventional monitoring methods. As already shown by jugular bulb measurements of oxygen and lactate, in the future clinicians will want to have access to continuous neurochemical information from the patient. This information could be used to prevent those enigmatic secondary lesions which play such a negative role in neurointensive medicine, or at least enable treatment of them at an early stage. The extensive information now available from the laboratory would help with the interpretation of clinical analogues. In the University Clinic of Neurosurgery in Basel we have been involved in the field of micro dialytic monitoring for several years and have recognised the problems, both technical and ethical, which are involved in taking the difficult step from animal experiments to clinical application. In 1994 we thought that research on clinical microdialysis had reached the stage which would enable scientists and clinicians to have many fruitful discussions.
Measurement of Cardiac Deformations from MRI: Physical and Mathematical Models (Computational Imaging and Vision #23)
by A. A. Amini Jerry L. PrinceMeasurement of Cardiac Deformations from MRI: Physical and Mathematical Models describes the latest imaging and imag analysis techniques that have been developed at leading centers for the visualization, analysis, and understanding of normal and abnormal cardiac motion with magnetic resonance imaging (MRI). The use of MRI in measuring cardiac motion is particularly important because MRI is non-invasive, and it is the only modality capable of imaging detailed intramural motion within the myocardium. Biomedical engineers, medical physicists, computer scientists, and physicians interested in learning about the latest advances in cardiovascular MRI should find this book to be a valuable educational resource. In particular, it is more tutorial in nature than most of the technical papers where the research was originally published. Practitioners and researchers working in the field of cardiovascular MRI will find the book to be filled with practical technical details and references to other work, enabling the implementation of existing methods and serving as a basis for further research in the area.
Utility of Bromelain and N-Acetylcysteine in Treatment of Peritoneal Dissemination of Gastrointestinal Mucin-Producing Malignancies
by Afshin Amini Samar Masoumi-Moghaddam David L. MorrisThis volume will describe both growth-inhibitory and mucin-depleting effects of bromelain and N-acetylcysteine, on their own or in combination, in cancer. It will coherently review the pathophysiological aspects of the mucin glycoproteins in malignancies and provide an updated account of the status of bromelain and N-acetylcysteine in cancer therapy. The volume will develop the idea of using these two drugs as a combination formulation for mucin-depleting effects.