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Aspergillus and Aspergillosis
by Hugo Van Den Bossche Geert Cauwenbergh Donald W. MacKenzieSpecies of aspergilli are common in man's environment and are responsible for a wide spectrum of human and animal disease, ranging in animals from mycotic abortion to aflatoxicosis and in humans from localized colonization of the ear or skin to life-threatening systemic infection of neutropenic patients. In recent times, invasive aspergillosis has become increasingly important as a cause of morbidity and death, initially in patients receiving immunosuppression prior to organ transplantation, and latterly in haematologic patients rendered neutropenic by underlying disease or chemotherapy. In some centres, the condition has been recorded in more than 40% of patients dying with acute leukaemia. Laboratory diagnostic procedures are not always helpful and the diagnosis depends largely on clinical parameters. The clinician is faced with yet another problem, that of management. At present, antifungal therapy of invasive aspergillosis can be largely ineffectual, and the mortality rate remains unacceptably high. Since Aspergillus fumigatus was first described almost 125 years ago, several other pathogenic species have been recognized. The marked biosynthetic abilities and varied mechanisms of gene recombination of aspergilli have long commanded attention in food technology and genetics. Their equally varied abilities to cause disease have attracted the interest of toxicologists, allergists and physicians concerned with infectious diseases.
Aspergirls: Empowering Females with Asperger Syndrome
by Rudy Simone*Gold Medal Winner in the Sexuality / Relationships Category of the 2011 IPPY Awards* * Honorary Mention in the 2010 BOTYA Awards Women's Issues Category * Girls with Asperger's Syndrome are less frequently diagnosed than boys, and even once symptoms have been recognised, help is often not readily available. The image of coping well presented by AS females of any age can often mask difficulties, deficits, challenges, and loneliness. This is a must-have handbook written by an Aspergirl for Aspergirls, young and old. Rudy Simone guides you through every aspect of both personal and professional life, from early recollections of blame, guilt, and savant skills, to friendships, romance and marriage. Employment, career, rituals and routines are also covered, along with depression, meltdowns and being misunderstood. Including the reflections of over thirty-five women diagnosed as on the spectrum, as well as some partners and parents, Rudy identifies recurring struggles and areas where Aspergirls need validation, information and advice. As they recount their stories, anecdotes, and wisdom, she highlights how differences between males and females on the spectrum are mostly a matter of perception, rejecting negative views of Aspergirls and empowering them to lead happy and fulfilled lives. This book will be essential reading for females of any age diagnosed with AS, and those who think they might be on the spectrum. It will also be of interest to partners and loved ones of Aspergirls, and anybody interested either professionally or academically in Asperger's Syndrome.
Aspergirls: Empowering Females with Asperger Syndrome (PDF)
by Rudy Simone*Gold Medal Winner in the Sexuality / Relationships Category of the 2011 IPPY Awards* * Honorary Mention in the 2010 BOTYA Awards Women's Issues Category * Girls with Asperger's Syndrome are less frequently diagnosed than boys, and even once symptoms have been recognised, help is often not readily available. The image of coping well presented by AS females of any age can often mask difficulties, deficits, challenges, and loneliness. This is a must-have handbook written by an Aspergirl for Aspergirls, young and old. Rudy Simone guides you through every aspect of both personal and professional life, from early recollections of blame, guilt, and savant skills, to friendships, romance and marriage. Employment, career, rituals and routines are also covered, along with depression, meltdowns and being misunderstood. Including the reflections of over thirty-five women diagnosed as on the spectrum, as well as some partners and parents, Rudy identifies recurring struggles and areas where Aspergirls need validation, information and advice. As they recount their stories, anecdotes, and wisdom, she highlights how differences between males and females on the spectrum are mostly a matter of perception, rejecting negative views of Aspergirls and empowering them to lead happy and fulfilled lives. This book will be essential reading for females of any age diagnosed with AS, and those who think they might be on the spectrum. It will also be of interest to partners and loved ones of Aspergirls, and anybody interested either professionally or academically in Asperger's Syndrome.
Asperkids: An Insider's Guide to Loving, Understanding and Teaching Children with Asperger Syndrome
by Jennifer Cook O'Toole Liane Holliday WilleyAs a parent, a teacher and an Aspie herself, Jennifer O'Toole provides the definitive insider's view of Asperger syndrome. She shows how to help children on the spectrum by understanding how they think and by exploiting their special interests to promote learning. Her strategies work because she thinks like the children that she teaches. This exciting book is full of effective and fun ways of engaging with children with Asperger syndrome. Jennifer explains how theory of mind difficulties create the need for concrete forms of communication, and provides original methods to inspire imagination through sensorial experiences. In particular she reveals the untapped power of special interests, showing how to harness these interests to encourage academic, social and emotional growth. Affirming that different doesn't mean defective, this book offers the insight and guidance that parents, educators, and other professionals need to connect with the Asperkids in their life and get them excited about learning.
Asperkids: An Insider's Guide to Loving, Understanding and Teaching Children with Asperger Syndrome (PDF)
by Jennifer Cook O'Toole Liane Holliday WilleyAs a parent, a teacher and an Aspie herself, Jennifer O'Toole provides the definitive insider's view of Asperger syndrome. She shows how to help children on the spectrum by understanding how they think and by exploiting their special interests to promote learning. Her strategies work because she thinks like the children that she teaches. This exciting book is full of effective and fun ways of engaging with children with Asperger syndrome. Jennifer explains how theory of mind difficulties create the need for concrete forms of communication, and provides original methods to inspire imagination through sensorial experiences. In particular she reveals the untapped power of special interests, showing how to harness these interests to encourage academic, social and emotional growth. Affirming that different doesn't mean defective, this book offers the insight and guidance that parents, educators, and other professionals need to connect with the Asperkids in their life and get them excited about learning.
The Asperkid's Game Plan: Extraordinary Minds, Purposeful Play... Ordinary Stuff
by Jennifer Cook O'TooleThe Asperkid's Game Plan looks from the inside at the learning style of children with Asperger syndrome and explains how to introduce structured play that engages Asperkids and explicitly addresses ASD weaknesses while reinforcing ASD strengths. Showing how just about anything can be turned into an opportunity for learning and growth, the book is full of go-to ideas for making simple play equipment in the home or classroom and using it to develop core skills that Asperkids struggle with, from fine motor and social skills, to planning and organization. Whether it's origami math, fried marbles, or a bug's eye view scavenger hunt, every game, project, and idea in the book is explained with clear directions and learning objectives and illustrated with color photographs. Jennifer O'Toole's enthusiastic approach and fun lessons, based on Montessori principles, will inspire and motivate parents, educators, and therapists to make purposeful play a part of every Asperkid's day.
The Asperkid's Game Plan: Extraordinary Minds, Purposeful Play... Ordinary Stuff (PDF)
by Jennifer Cook O'TooleThe Asperkid's Game Plan looks from the inside at the learning style of children with Asperger syndrome and explains how to introduce structured play that engages Asperkids and explicitly addresses ASD weaknesses while reinforcing ASD strengths. Showing how just about anything can be turned into an opportunity for learning and growth, the book is full of go-to ideas for making simple play equipment in the home or classroom and using it to develop core skills that Asperkids struggle with, from fine motor and social skills, to planning and organization. Whether it's origami math, fried marbles, or a bug's eye view scavenger hunt, every game, project, and idea in the book is explained with clear directions and learning objectives and illustrated with color photographs. Jennifer O'Toole's enthusiastic approach and fun lessons, based on Montessori principles, will inspire and motivate parents, educators, and therapists to make purposeful play a part of every Asperkid's day.
The Asperkid's Launch Pad: Home Design to Empower Everyday Superheroes
by Jennifer Cook O'TooleFor Asperkids, home is both their protected lair and their launch pad into success in a neurotypical world. Jennifer O'Toole provides parents with all the help they need in planning their home environment to encourage their Asperkid superheroes to soar. The Asperkid's Launch Pad is a visually-led guide to preparing a home environment that supports the development of children with Asperger syndrome. From a bedroom light switch that the child can easily reach, to a tucked-away safe place that he or she can retreat to when feeling overwhelmed or anxious, small changes in the home can boost the child's self-confidence, independence, comfort and life skills. Award-winning author Jennifer O'Toole gives readers a walk-through tour of the home, showing, room by room, how physical surroundings affect Asperkids and highlighting the learning opportunities in every space and object. Beautifully presented with color photographs throughout, this functional and fun book will win a place in the homes and hearts of all parents of children with Asperger syndrome.
The Asperkid's Launch Pad: Home Design to Empower Everyday Superheroes (PDF)
by Jennifer Cook O'TooleFor Asperkids, home is both their protected lair and their launch pad into success in a neurotypical world. Jennifer O'Toole provides parents with all the help they need in planning their home environment to encourage their Asperkid superheroes to soar. The Asperkid's Launch Pad is a visually-led guide to preparing a home environment that supports the development of children with Asperger syndrome. From a bedroom light switch that the child can easily reach, to a tucked-away safe place that he or she can retreat to when feeling overwhelmed or anxious, small changes in the home can boost the child's self-confidence, independence, comfort and life skills. Award-winning author Jennifer O'Toole gives readers a walk-through tour of the home, showing, room by room, how physical surroundings affect Asperkids and highlighting the learning opportunities in every space and object. Beautifully presented with color photographs throughout, this functional and fun book will win a place in the homes and hearts of all parents of children with Asperger syndrome.
The Asperkid's (Secret) Book of Social Rules: The Handbook of Not-So-Obvious Social Guidelines for Tweens and Teens with Asperger Syndrome
by Brian Bojanowski Jennifer Cook O'TooleBeing a teen or tween isn't easy for anyone but it can be especially tough for Asperkids. Jennifer O'Toole knows; she was one! This book is a top secret guide to all of the hidden social rules in life that often seem strange and confusing to young people with Asperger syndrome. The Asperkid's (Secret) Book of Social Rules offers witty and wise insights into baffling social codes such as making and keeping friends, blending in versus standing out from the crowd, and common conversation pitfalls. Chock full of illustrations, logical explanations, and comic strip practice sessions, this is the handbook that every adult Aspie wishes they'd had growing up. Ideal for all 10-17 year olds with Asperger syndrome, this book provides inside information on over thirty social rules in bite-sized chunks that older children will enjoy, understand, and most importantly use daily to navigate the mysterious world around them.
The Asperkid's (Secret) Book of Social Rules: The Handbook of Not-So-Obvious Social Guidelines for Tweens and Teens with Asperger Syndrome (PDF)
by Brian Bojanowski Jennifer Cook O'TooleBeing a teen or tween isn't easy for anyone but it can be especially tough for Asperkids. Jennifer O'Toole knows; she was one! This book is a top secret guide to all of the hidden social rules in life that often seem strange and confusing to young people with Asperger syndrome. The Asperkid's (Secret) Book of Social Rules offers witty and wise insights into baffling social codes such as making and keeping friends, blending in versus standing out from the crowd, and common conversation pitfalls. Chock full of illustrations, logical explanations, and comic strip practice sessions, this is the handbook that every adult Aspie wishes they'd had growing up. Ideal for all 10-17 year olds with Asperger syndrome, this book provides inside information on over thirty social rules in bite-sized chunks that older children will enjoy, understand, and most importantly use daily to navigate the mysterious world around them.
The Asperkid's (Secret) Book of Social Rules, 10th Anniversary Edition: The Handbook of (Not-So-Obvious) Neurotypical Social Guidelines for Autistic Teens
by Jennifer CookBeing a teen or tween is tough for anyone. And if you're on the Autism Spectrum, life can feel like a game you're playing without knowing the rules. Jennifer Cook knows - she's been there! Her internationally bestselling handbook is the key to unlocking those unwritten, often confusing, not-so-obvious social guidelines and bolstering confidence, all at once. Finally, teens can play the game of life with instructions. The 10th Anniversary Edition of The (Secret) Book of Social Rules reveals the essential secrets behind the baffling social codes surrounding making and keeping friends, dating, and catastrophic conversation pitfalls, with all-new content on social media and talking about neurodiversity. It's no wonder Jennifer's is the navigation tool tens of thousands of fans have come to love! Full of brand-new funny illustrations, take-it-from-me explanations, and comic strip examples, this Book of the Year award winner is real, positive, and speaks from the heart (without ever sounding like your mother's guide to manners). It's confidence, humor, and smarts. For the Human Spectrum.
The Asperkid's (Secret) Book of Social Rules, 10th Anniversary Edition: The Handbook of (Not-So-Obvious) Neurotypical Social Guidelines for Autistic Teens
by Jennifer CookBeing a teen or tween is tough for anyone. And if you're on the Autism Spectrum, life can feel like a game you're playing without knowing the rules. Jennifer Cook knows - she's been there! Her internationally bestselling handbook is the key to unlocking those unwritten, often confusing, not-so-obvious social guidelines and bolstering confidence, all at once. Finally, teens can play the game of life with instructions. The 10th Anniversary Edition of The (Secret) Book of Social Rules reveals the essential secrets behind the baffling social codes surrounding making and keeping friends, dating, and catastrophic conversation pitfalls, with all-new content on social media and talking about neurodiversity. It's no wonder Jennifer's is the navigation tool tens of thousands of fans have come to love! Full of brand-new funny illustrations, take-it-from-me explanations, and comic strip examples, this Book of the Year award winner is real, positive, and speaks from the heart (without ever sounding like your mother's guide to manners). It's confidence, humor, and smarts. For the Human Spectrum.
The Aspern Papers (Oxford World's Classics)
by Leon Edel Adrian Poole'There's no baseness I wouldn't commit for Jeffrey Aspern's sake.' The poet Aspern, long since dead, has left behind some private papers. They are jealously guarded by an old lady, once his mistress and muse, a recluse in an old palazzo in Venice, tended by her ingenuous niece. A predatory critic is determined to seize them. What can he make of the younger woman? What are his motives? What are the papers worth and what is he prepared to pay? In all four stories collected here, including 'The Death of the Lion', 'The Figure in the Carpet', and 'The Birthplace', the figure of the artist is central. Extraordinarily prophetic, James explores the emergent new cult of the writer as celebrity, and asks, who cares about the work for itself? Can the man behind the artist ever truly be known, and does our knowledge explain the act of creativity? This new edition includes extracts from James's Prefaces and Notebooks which shed light on the genesis of the stories. ABOUT THE SERIES: For over 100 years Oxford World's Classics has made available the widest range of literature from around the globe. Each affordable volume reflects Oxford's commitment to scholarship, providing the most accurate text plus a wealth of other valuable features, including expert introductions by leading authorities, helpful notes to clarify the text, up-to-date bibliographies for further study, and much more.
Aspetti psicologici nella sclerosi multipla: Dalla diagnosi alla gestione della malattia
by Silvia BoninoQuesto volume è rivolto agli psicologi che si occupano di persone con sclerosi multipla e si propone di fornire loro un aggiornamento sulle problematiche psicologiche e relazionali legate alla malattia, basato sul concetto dell’evidence-based practice. Gli argomenti trattati includono alcuni concetti di base relativi a questa patologia, gli aspetti psicologici, emotivi e cognitivi legati alla sua diagnosi, terapia e decorso, la gestione delle relazioni familiari e la riabilitazione. Per consentire al lettore di avere un panorama completo, la trattazione prende in considerazione sia gli aspetti teorici che pratici. Il libro nasce da una proposta dell’Associazione Italiana Sclerosi Multipla (AISM), promotrice del progetto Rete Psicologi che opera sul territorio a sostegno di pazienti e famiglie.
Asphalt Children and City Streets: A Life, A City, And A Case Study Of History, Culture, And Ethnomathematics In São Paulo
by Mônica Mesquita Sal Restivo Ubiratan D’AmbrosioThis work explores the urban experiences of street children in sao paulo, brazil through the mathematical epistemic regimes at the core of their survival strategies. We also draw attention to the situation of street children across time, space, culture, and history. Our goal is to recognize, understand, and validate forms of mathematics constructed and used outside of the established institutions of mathematical production. We base our analysis on "the mathematical imagination", which draws together social constructionism and ethnomathematics. Theoretically, we draw heavily on the durkheimian tradition in sociology and anthropology. We focus on a form of practice that links the formal and the informal in order to realize the full power of mathematical knowledge as a social thing (in durkheim's sense), a product of the collective consciousness that expresses collective realities and a category of knowledge present in every culture. This is as true for mathematics at the margins as it is for professional mathematics. Our work contributes to an emerging political manifesto of the marginal that demonstrates the social realities and social power of their mathematics. This book should be of interest to social scientists, students of mathematics and ethnomathematics, and everyone interested in the situation of marginalized children.
Asphalt Mixture Selection
by Cliff Nicholls Arthur HannahThis practical guide starts with a survey of the types of site and the asphalt properties which are required. Various external influences which may affect the relative importance of some properties are addressed, and the interplay of sites and external is considered. Asphalt mixture types and their properties are reviewed, largely as defined in the EN 13108 series but subdivided into further categories, and into maximum nominal coarse aggregate sizes using EN 13043 basic set plus set 2 sizes. Guidance is given, including using flowcharts, of the different mixtures that are suitable for each situation. In some cases a range of choices or mixtures with different degrees of suitability is offered. The guidance covers surface course, binder course and base, but with more focus on the surface course where the external influence is most significant. The site and external influence combinations on which a mixture can be used successfully are also given. The book is primarily intended for those who select asphalt on an occasional basis, such as architects or housing developers, but could be of use to other engineers with limited experience. It is also useful as an educational textbook for those studying asphalt technology.
Asphalt Mixture Selection
by Cliff Nicholls Arthur HannahThis practical guide starts with a survey of the types of site and the asphalt properties which are required. Various external influences which may affect the relative importance of some properties are addressed, and the interplay of sites and external is considered. Asphalt mixture types and their properties are reviewed, largely as defined in the EN 13108 series but subdivided into further categories, and into maximum nominal coarse aggregate sizes using EN 13043 basic set plus set 2 sizes. Guidance is given, including using flowcharts, of the different mixtures that are suitable for each situation. In some cases a range of choices or mixtures with different degrees of suitability is offered. The guidance covers surface course, binder course and base, but with more focus on the surface course where the external influence is most significant. The site and external influence combinations on which a mixture can be used successfully are also given. The book is primarily intended for those who select asphalt on an occasional basis, such as architects or housing developers, but could be of use to other engineers with limited experience. It is also useful as an educational textbook for those studying asphalt technology.
Asphalt Mixture Specification and Testing
by Cliff NichollsThis guide reviews the way asphalt mixture can be specified, with particular emphasis on the test methods used to measure performance. The advantages and limitations of the tests are described for measuring the desired property, and engineers can specify a test according to the material’s use. The book starts with a resume of specifications and their relative advantages and disadvantages for different situations. Then different properties are discussed in terms of: their specification; the test methods that can be used (primarily the EN 12697 suite of European methods, of which the author has been responsible for drafting); the extent to which the results predict performance; the levels that can be achieved with different asphalt mixes and types; what levels, if any, should be specified in various situations and pavement layers; and which other properties are adversely affected by enhanced performance. The final section covers various aspects of sustainability, with a strong emphasis on durability. Better understanding should enable clients and consultants who specify pavements to produce durable asphalt pavements more economically, and also help asphalt producers and students trying to understand the black art of asphalt.
Asphalt Mixture Specification and Testing
by Cliff NichollsThis guide reviews the way asphalt mixture can be specified, with particular emphasis on the test methods used to measure performance. The advantages and limitations of the tests are described for measuring the desired property, and engineers can specify a test according to the material’s use. The book starts with a resume of specifications and their relative advantages and disadvantages for different situations. Then different properties are discussed in terms of: their specification; the test methods that can be used (primarily the EN 12697 suite of European methods, of which the author has been responsible for drafting); the extent to which the results predict performance; the levels that can be achieved with different asphalt mixes and types; what levels, if any, should be specified in various situations and pavement layers; and which other properties are adversely affected by enhanced performance. The final section covers various aspects of sustainability, with a strong emphasis on durability. Better understanding should enable clients and consultants who specify pavements to produce durable asphalt pavements more economically, and also help asphalt producers and students trying to understand the black art of asphalt.
Asphalt Pavements
by Y. Richard KimAsphalt Pavements contains the proceedings of the International Conference on Asphalt Pavements (Raleigh, North Carolina, USA, 1-5 June 2014), and discusses recent advances in theory and practice in asphalt materials and pavements. The contributions cover a wide range of topics:- Environmental protection and socio-economic impacts- Additives and mo
Asphalt Pavements: A Practical Guide to Design, Production and Maintenance for Engineers and Architects
by Patrick LavinAsphalt Pavements provides the know-how behind the design, production and maintenance of asphalt pavements and parking lots. Incorporating the latest technology, this book is the first to focus primarily on the design, production and maintenance of low-volume roads and parking areas.Special attention is given to determining the traffic capacity, re
Asphalt- und Teerstraßen: Bituminöse Straßenanlagen
by Bernard Johan Kerkhof Emil IlseDieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.
Asphaltene Deposition: Fundamentals, Prediction, Prevention, and Remediation
by Francisco M. Vargas and Mohammad TavakkoliAs global consumption of fossil fuels such as oil increases, previously abundant sources have become depleted or plagued with obstructions. Asphaltene deposition is one of such obstructions which can significantly decrease the rate of oil production. This book offers concise yet thorough coverage of the complex problem of asphaltene precipitation and deposition in oil production. It covers fundamentals of chemistry, stabilization theories and mechanistic approaches of asphaltene behavior at high temperature and pressure. Asphaltene Deposition: Fundamentals, Prediction, Prevention, and Remediation explains techniques for experimental determination of asphaltene precipitation and deposition and different modeling tools available to forecast the occurrence and magnitude of asphaltene deposition in a given oil field. It discusses strategies for mitigation of asphaltene deposition using chemical inhibition and corresponding challenges, best practices for asphaltene remediation, current research, and case studies.
Asphaltene Deposition: Fundamentals, Prediction, Prevention, and Remediation
by Francisco M. Vargas Mohammad TavakkoliAs global consumption of fossil fuels such as oil increases, previously abundant sources have become depleted or plagued with obstructions. Asphaltene deposition is one of such obstructions which can significantly decrease the rate of oil production. This book offers concise yet thorough coverage of the complex problem of asphaltene precipitation and deposition in oil production. It covers fundamentals of chemistry, stabilization theories and mechanistic approaches of asphaltene behavior at high temperature and pressure. Asphaltene Deposition: Fundamentals, Prediction, Prevention, and Remediation explains techniques for experimental determination of asphaltene precipitation and deposition and different modeling tools available to forecast the occurrence and magnitude of asphaltene deposition in a given oil field. It discusses strategies for mitigation of asphaltene deposition using chemical inhibition and corresponding challenges, best practices for asphaltene remediation, current research, and case studies.