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Advancing Clinical Governance

by Jonathon Secker-Walker Myriam Lugon

The follow-up to Clinical Governance - Making it Happen considers the implications of clinical governance for a wide range of health care professionals including nurses, medical directors and chief executives. The contributors examine the role of the new government organisation NICE, the responsibilities of those working for NHS organisations and the benefits of patient involvement. Advancing Clinical Governance will enable health professionals to implement clinical governance effectively and with confidence.

Advancing Development of Synthetic Gene Regulators: With the Power of High-Throughput Sequencing in Chemical Biology (Springer Theses)

by Anandhakumar Chandran

This book focuses on an “outside the box” notion by utilizing the powerful applications of next-generation sequencing (NGS) technologies in the interface of chemistry and biology. In personalized medicine, developing small molecules targeting a specific genomic sequence is an attractive goal. N-methylpyrrole (P)–N-methylimidazole (I) polyamides (PIPs) are a class of small molecule that can bind to the DNA minor groove. First, a cost-effective NGS (ion torrent platform)-based Bind-n-Seq was developed to identify the binding specificity of PIP conjugates in a randomized DNA library. Their biological influences rely primarily on selective DNA binding affinity, so it is important to analyze their genome-wide binding preferences. However, it is demanding to enrich specifically the small-molecule-bound DNA without chemical cross-linking or covalent binding in chromatinized genomes. Herein is described a method that was developed using high-throughput sequencing to map the differential binding sites and relative enriched regions of non-cross-linked SAHA-PIPs throughout the complex human genome. SAHA-PIPs binding motifs were identified and the genome-level mapping of SAHA-PIPs-enriched regions provided evidence for the differential activation of the gene network. A method using high-throughput sequencing to map the binding sites and relative enriched regions of alkylating PIP throughout the human genome was also developed. The genome-level mapping of alkylating the PIP-enriched region and the binding sites on the human genome identifies significant genomic targets of breast cancer. It is anticipated that this pioneering low-cost, high through-put investigation at the sequence-specific level will be helpful in understanding the binding specificity of various DNA-binding small molecules, which in turn will be beneficial for the development of small-molecule-based drugs targeting a genome-level sequence.

Advancing Dietetics and Clinical Nutrition E-Book

by Anne Payne Helen Barker

This book provides a comprehensive account of the relevant physiology, pathophysiology, nutritional therapy and dietetic application for each specialist dietetic area. All major specialist areas involved in the the treatment of adults are covered. The first section deals with clinical governance, for example patient-centred care, clinical decision-making and developing evidence-based practice. The second section on advanced clinical practice describes 18 clinical conditions or dietetic areas in detail. There is detailed coverage of 18 clinical conditions or dietetic areas: The control of food intake and absorption of nutrients Drug nutrient interactions Food allergy – allergy and intolerance Irritable bowel disease (IBD) and colorectal cancer Short bowel syndrome Enteral nutrition Parenteral nutrition Thermal injury Nutrition and liver disease HIV Palliative care Renal disease Diabetes Obesity Cardiovascular disease Stroke Neurological conditions Mental health. Each chapter concludes with a section on possible future developments in the specialty, providing insight into 'hot topics', making this an essential text for all working in the field of Dietetics and Clinical Nutrition.Each clinical chapter follows a standard structure: Learning objectives Key points summarise important aspects Case studies with questions and answers help link theory to practice References and further reading suggestions encourage wider research.

Advancing Federal Sector Health Care: A Model for Technology Transfer (Health Informatics)

by Peter Ramsaroop

This book focuses on todays attempts to reshape the federal healthcare system. The major strength of the text lies in its use of examples that show how process redesign and the integration of enabling technologies lead to performance improvement and cost reduction. The contributors draw upon their knowledge and experience of the federal healthcare industry. Rather than intending to provide readers with the correct answers the authors map out the various new approaches.

Advancing Frontiers in Mycology & Mycotechnology: Basic and Applied Aspects of Fungi

by Tulasi Satyanarayana Sunil Kumar Deshmukh Mukund V. Deshpande

The book provides an introduction to the basics of fungi, discussing various types ranging from edible mushrooms to Neurospora – a model system for genetics and epigenetics. After addressing the classification and biodiversity of fungi, and fungi in different ecological niches, it describes the latest applications of fungi, their role in sustainable environments and in alleviating stress in plants, as well as their role in causing plant and animal diseases. Further chapters explore the advances in fungal interactions research and their implications for various systems, and discuss plant-pathogen interactions. The book also features a section on bioprospecting, and is an extremely interesting and informative read for anybody involved in the field of mycology, microbiology and biotechnology teaching and research.

Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics (Springer Theses)

by Kevin M. Koo

This book presents a unique concept of merging nanotechnology and novel urinary biomarkers for accurate early prostate cancer detection, discussing an entire progressive pipeline of innovative new strategies in biosensor development, from a simple colorimetric system to a complex system for simultaneous multiple biomarker sensing. For newcomers to the field of nucleic acid biosensing, it also describes various isothermal amplification and amplification-free strategies, which are currently the main research areas. Lastly, the book introduces and demonstrates the notion of clinical nanobiosensor validation toward clinical translation: the ultimate aim of researchers in the biosensor field. This book is a valuable reference resource learners seeking inspiration for cancer biosensor development.

Advancing Health and Well-Being: Using Evidence and Collaboration to Achieve Health Equity (Culture of Health)

by Alonzo L . Plough, PHD, MPH, MA

The case for evidence and collaboration in pursuit of health equity In this second volume of the Culture of Health series, Advancing Health and Well-Being convenes experts from academia, policy, journalism, and community-based organizations, among other sectors, to examine how data and narrative can catalyze progress toward building a national Culture of Health. Tackling topics such as health inequity, mass incarceration, and climate change, Advancing Health and Well-Being does more than draw lines between cause and effect; its 70+ voices lend context and lived experience to critical conversations that may lack such elements. The result is a work that shows the power and promise of evidence and collaboration. Amid continued interest in population health and well-being, this book offers essential reading for those advancing such efforts, and those seeking an early grounding, in pursuit of a Culture of Health.

Advancing Health and Well-Being: Using Evidence and Collaboration to Achieve Health Equity (Culture of Health)


The case for evidence and collaboration in pursuit of health equity In this second volume of the Culture of Health series, Advancing Health and Well-Being convenes experts from academia, policy, journalism, and community-based organizations, among other sectors, to examine how data and narrative can catalyze progress toward building a national Culture of Health. Tackling topics such as health inequity, mass incarceration, and climate change, Advancing Health and Well-Being does more than draw lines between cause and effect; its 70+ voices lend context and lived experience to critical conversations that may lack such elements. The result is a work that shows the power and promise of evidence and collaboration. Amid continued interest in population health and well-being, this book offers essential reading for those advancing such efforts, and those seeking an early grounding, in pursuit of a Culture of Health.

Advancing Health and Wellbeing in the Changing Urban Environment: Implementing a Systems Approach (Urban Health and Wellbeing)

by Franz W. Gatzweiler Yong-Guan Zhu Anna V. Diez Roux Anthony Capon Christel Donnelly Gérard Salem Hany M. Ayad Ilene Speizer Indira Nath Jo I. Boufford Keisuke Hanaki Luuk C. Rietveld Pierre Ritchie Saroj Jayasinghe Susan Parnell Yi Zhang

This book addresses up-to-date urban health issues from a systems perspective and provides an appealing integrated urban development strategy based on a 10-year global interdisciplinary research programme created by the International Council for Science (ICSU), and sponsored by the InterAcademy Partnership (IAP) and the United Nations University (UNU). The unique feature of this book is its “systems approach” to urban health and wellbeing: solution-oriented for science and society and not purely theoretical, it can be applied in the context of decision-making, and has the potential to unlock cities’ unused potential by promoting health and wellbeing. Furthermore, the inter- and transdisciplinary urban issues addressed in this book are examined from a cross-sectoral perspective – e.g. the transport sector is addressed in connection with air pollution, respiratory and cardiovascular diseases and the loss of productivity. The interconnected thinking to urban health and wellbeing makes the book a particularly valuable resource. Decision makers in city administrations and civil society organizations from different geographical regions will find the book an informative and inspiring guide for delivering towards the goals of the New Urban Agenda, for which health can be the vital indicator of progress. Graduate students and researchers will be attracted by the case studies, systems methods and models provided in the book.

Advancing Health Literacy: A Framework for Understanding and Action (Jossey-Bass Public Health #17)

by Christina Zarcadoolas Andrew Pleasant David S. Greer

Advancing Health Literacy addresses the crisis in health literacy in the United States and around the world. This book thoroughly examines the critical role of literacy in public health and outlines a practical, effective model that bridges the gap between health education, health promotion, and health communication. Step by step, the authors outline the theory and practice of health literacy from a public health perspective. This comprehensive resource includes the history of health literacy, theoretical foundations of health and language literacy, the role of the media, a series of case studies on important topics including prenatal care, anthrax, HIV/AIDS, genomics, and diabetes. The book concludes with a series of practical guidelines for the development and assessment of health communications materials. Also included are essential techniques needed to help people make informed decisions, advocate for themselves and their community, mitigate risk, and live healthier lives.

Advancing Health Literacy: A Framework for Understanding and Action (Jossey-Bass Public Health #17)

by Christina Zarcadoolas Andrew Pleasant David S. Greer

Advancing Health Literacy addresses the crisis in health literacy in the United States and around the world. This book thoroughly examines the critical role of literacy in public health and outlines a practical, effective model that bridges the gap between health education, health promotion, and health communication. Step by step, the authors outline the theory and practice of health literacy from a public health perspective. This comprehensive resource includes the history of health literacy, theoretical foundations of health and language literacy, the role of the media, a series of case studies on important topics including prenatal care, anthrax, HIV/AIDS, genomics, and diabetes. The book concludes with a series of practical guidelines for the development and assessment of health communications materials. Also included are essential techniques needed to help people make informed decisions, advocate for themselves and their community, mitigate risk, and live healthier lives.

Advancing Healthcare Through Personalized Medicine

by Priya Hays

This innovative book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it will help mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to underlying concepts at the heart of personalized medicine - pharmacogenomics, targeted therapies and individualized diagnosis and treatment - and shows how, with the advent of genomic technologies, clinicians will have the capability to predict and diagnose disease more efficiently. Advocating a patient-centred approach at the heart of care, this introduction to personalized medicine, the science behind it, its economic effects, its effects upon patients and its overall implications for society will be invaluable to clinicians, to healthcare providers and to patients.

Advancing Healthcare Through Personalized Medicine

by Priya Hays

This book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it helps to mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to the underlying concepts at the heart of personalized medicine. An innovative second edition, this book functions as an update to the successful first edition to include new, state-of-the-art information and advancements in the fast-paced field of personalized medicine.Chapters examine pharmacogenomics, targeted therapies, individualized diagnosis and treatment, and cancer immunotherapies. The book also features an essential discussion on how the advent of genomic technologies gives clinicians the capability to predict and diagnose disease more efficiently and offers a detailed up-to-date compilation of clinical trials in cancer leading to breakthrough therapies. The book also addresses the impact of Big Data on personalized medicine and the newfound applications of digital health and artificial intelligence. A work that advocates for a patient-centered approach, Advancing Healthcare Through Personalized Medicine, Second Edition is an invaluable text for clinicians, healthcare providers, and patients.

Advancing Healthcare Through Personalized Medicine

by Priya Hays

This innovative book provides a unique perspective on the biomedical and societal implications of personalized medicine and how it will help mitigate the healthcare crisis and rein in ever-growing expenditure. It introduces the reader to underlying concepts at the heart of personalized medicine - pharmacogenomics, targeted therapies and individualized diagnosis and treatment - and shows how, with the advent of genomic technologies, clinicians will have the capability to predict and diagnose disease more efficiently. Advocating a patient-centred approach at the heart of care, this introduction to personalized medicine, the science behind it, its economic effects, its effects upon patients and its overall implications for society will be invaluable to clinicians, to healthcare providers and to patients.

Advancing Medical Posthumanism Through Twenty-First Century American Poetry (Palgrave Studies in Literature, Science and Medicine)

by Tana Jean Welch

Advancing Medical Posthumanism Through Twenty-First Century American Poetry places contemporary poetics in dialogue with posthumanism and biomedicine in order to create a framework for advancing a posthuman-affirmative ethics within the culture of medical practice. This book makes a case for a posthumanist understanding of the body—one that sees health and illness not as properties possessed by individual bodies, but as processes that connect bodies to their social and natural environment, shaping their capacity to act, think, and feel. Tana Jean Welch demonstrates how contemporary American poetry is specifically poised to develop a pathway toward a posthuman intervention in biomedicine, the field of medical humanities, medical discourse, and the value systems that guide U.S. healthcare in general.

Advancing Nursing Practice in Cancer and Palliative Care

by David Clarke Jean Flanagan Kevin Kendrick

Advancing Practice in Cancer and Palliative Care critically explores and analyses the themes and pragmatics of advancing nursing practice in relation to cancer and palliative care. Written by a team of experienced practitioners and educationalists, each chapter considers key elements of advanced practice in terms of conceptual, practical and organisational themes. Case studies are used throughout to encourage the reader to take a reflective stance on the way in which the themes of the text can be applied to practice. The book will be a useful resource for cancer and palliative care nurses wanting to advance and lead practice effectively.

Advancing Nursing Practice in Pain Management

by Eloise Carr Mandy Layzell Martin Christensen

This book showcases the development and evaluation of innovative examples of pain management initiatives by advanced practitioners. It considers each service development or community initiative both in terms of advanced practice nursing and pain management. There is a wide range of examples of innovation in pain management included – from the introduction of ketamine use in one trust, to wider issues around meeting the needs of pain management in the community. The book considers issues including use of research, education and interprofessional working in the advanced practitioner role. Each chapter looks at development of the service, challenges of implementation, evaluation of the service’s success and justifying the importance of the advanced nurse in the service’s achievements. Underlying theory is considered but the focus of each chapter is the translation of knowledge and skills into practice Written by expert advanced nurse practitioners with a wealth of experience in pain management Explores pain management in primary and secondary care, both within and outside the NHS Suitable for qualified nurses, Nurse Practitioners, specialist nurses working in the pain field and nursing students on postgraduate courses on pain management

Advancing Occupational Therapy in Mental Health Practice

by Elizabeth McKay Christine Craik Kee Hean Lim Gabrielle Richards

Advancing Occupational Therapy in Mental Health Practice looks at the contribution that occupational therapists make to the lives of clients living with mental illness. It examines current practice developments and the innovative research that is shaping occupational therapy within the mental health arena, nationally and internationally. The book employs a distinctive and engaging narrative approach, bringing to life key issues in practice and research. It introduces the reader to the mental health context, opening with a historical overview and then exploration of the current developments in occupational therapy before moving on to discuss the cultural context and the need for cultural sensitivity in practice. Service users and expert clinicians offer their narratives, through which the clinical utility and cultural appropriateness of existing occupational therapy concepts, assessments and outcome measures are discussed and the associated implications for practice highlighted. Advancing Occupational Therapy in Mental Health Practice introduces and explores a variety of specialised work contexts from practicing in acute inpatient settings to crisis intervention, home treatment, forensic mental health settings and the specialist role of occupational therapy in community mental health and social services. Chapters are enriched with case stories, personal narratives and guided reflection.

Advancing Occupational Therapy in Mental Health Practice

by Elizabeth McKay Christine Craik Kee Hean Lim Gabrielle Richards

Advancing Occupational Therapy in Mental Health Practice looks at the contribution that occupational therapists make to the lives of clients living with mental illness. It examines current practice developments and the innovative research that is shaping occupational therapy within the mental health arena, nationally and internationally. The book employs a distinctive and engaging narrative approach, bringing to life key issues in practice and research. It introduces the reader to the mental health context, opening with a historical overview and then exploration of the current developments in occupational therapy before moving on to discuss the cultural context and the need for cultural sensitivity in practice. Service users and expert clinicians offer their narratives, through which the clinical utility and cultural appropriateness of existing occupational therapy concepts, assessments and outcome measures are discussed and the associated implications for practice highlighted. Advancing Occupational Therapy in Mental Health Practice introduces and explores a variety of specialised work contexts from practicing in acute inpatient settings to crisis intervention, home treatment, forensic mental health settings and the specialist role of occupational therapy in community mental health and social services. Chapters are enriched with case stories, personal narratives and guided reflection.

Advancing Practice in Rehabilitation Nursing

by Rebecca Jester

Nurses play a key role in the rehabilitation process - maximising the quality of life and independence of individuals following trauma, disease or enduring chronic illness. Advancing Practice in Rehabilitation Nursing provides an in-depth analysis of specialist practice in rehabilitation nursing. It examines the research basis underlying clinical practice and identifies unique attributes of the nursing role within the context of multidisciplinary and multi-agency working. The first part of Advancing Practice in Rehabilitation Nursing explores general principles of specialist rehabilitation practice, which can be applied to both community and in-patient settings. The second part addresses specific issues in core areas of practice including stroke, acquired brain injury, spinal injury, orthopaedic rehabilitation and management of people with long-term conditions.

Advancing Professional Development through CPE in Public Health (Global Science Education)

by Yashwant V. Pathak Ira Nurmala

The education division is a prominent part of the public health profession. It focuses on educating individuals and communities to promote health and prevent disease. The educators are drawn from a diverse range of disciplines and defined as professionally prepared individuals who serve in a variety of roles using appropriate educational strategies and methods to facilitate the development of policies, procedures, interventions, and systems conducive to the health of individuals.This unique volume in the Global Science Education Series describes some of the challenges faced by this profession in helping the audience to understand public health and solve health issues. Key Features: Aids researchers in designing an evaluation study in CPE for health professions and related fields Presents data on how public health practice comprises of individuals working together toward promoting population health Covers continuing professional education in the US and how it can be adopted globally Discusses the Kirkpatrick’s four-level evaluation model at length Demonstrates how questionnaires are preferable in evaluating CPE programs due to their cost effectiveness and being user friendly

Advancing Professional Development through CPE in Public Health (Global Science Education)

by Yashwant V. Pathak Ira Nurmala

The education division is a prominent part of the public health profession. It focuses on educating individuals and communities to promote health and prevent disease. The educators are drawn from a diverse range of disciplines and defined as professionally prepared individuals who serve in a variety of roles using appropriate educational strategies and methods to facilitate the development of policies, procedures, interventions, and systems conducive to the health of individuals.This unique volume in the Global Science Education Series describes some of the challenges faced by this profession in helping the audience to understand public health and solve health issues. Key Features: Aids researchers in designing an evaluation study in CPE for health professions and related fields Presents data on how public health practice comprises of individuals working together toward promoting population health Covers continuing professional education in the US and how it can be adopted globally Discusses the Kirkpatrick’s four-level evaluation model at length Demonstrates how questionnaires are preferable in evaluating CPE programs due to their cost effectiveness and being user friendly

Advancing Sexual and Reproductive Health and Rights in Africa: Constraints and Opportunities (ISSN)

by Ebenezer Durojaye Gladys Mirugi-Mukundi Charles Ngwena

This book explores recent developments, constraints and opportunities relating to the advancement of sexual and reproductive health and rights in Africa.Despite many positive developments in relation to sexual and reproductive health in recent years, many Africans still encounter challenges, for instance in poor maternity services, living with HIV, and discrimination on the basis of age, gender, sexual orientation or identity. Covering topics such as abortion, gender identity, adolescent sexuality and homosexuality, the chapters in this book discuss the impact of culture, morality and social beliefs on the enjoyment of sexual and reproductive health and rights across the continent, particularly in relation to vulnerable and marginalized groups. The book also explores the role of litigation, national human rights institutions and regional human rights bodies in advancing the realization of sexual and reproductive health and rights in the region. Throughout, the contributions highlight the relevance of a rights-based framework in addressing topical and contentious issues on sexual and reproductive health and rights within Sub-Saharan Africa.This book will be of interest to researchers of sexuality, civil rights and health in Africa.The Open Access version of this book, available at http://www.taylorfrancis.com/books/e/9781003175049, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.

Advancing Sexual and Reproductive Health and Rights in Africa: Constraints and Opportunities (ISSN)

by Ebenezer Durojaye Gladys Mirugi-Mukundi Charles Ngwena

This book explores recent developments, constraints and opportunities relating to the advancement of sexual and reproductive health and rights in Africa.Despite many positive developments in relation to sexual and reproductive health in recent years, many Africans still encounter challenges, for instance in poor maternity services, living with HIV, and discrimination on the basis of age, gender, sexual orientation or identity. Covering topics such as abortion, gender identity, adolescent sexuality and homosexuality, the chapters in this book discuss the impact of culture, morality and social beliefs on the enjoyment of sexual and reproductive health and rights across the continent, particularly in relation to vulnerable and marginalized groups. The book also explores the role of litigation, national human rights institutions and regional human rights bodies in advancing the realization of sexual and reproductive health and rights in the region. Throughout, the contributions highlight the relevance of a rights-based framework in addressing topical and contentious issues on sexual and reproductive health and rights within Sub-Saharan Africa.This book will be of interest to researchers of sexuality, civil rights and health in Africa.The Open Access version of this book, available at http://www.taylorfrancis.com/books/e/9781003175049, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.

Advancing Skills in Midwifery Practice E-Book

by Jayne E. Marshall Maureen D. Raynor Paul Lewis

Advancing Skills in Midwifery Practice provides a guide to continuing professional development needs and meeting the latest Post-Registration and Practice (PREP) requirements. Building on Skills for Midwifery Practice by Ruth Johnson and Wendy Taylor, this book follows a similar format already familiar to many midwives. Whilst aimed primarily at registered midwives, the principles and philosophy apply across interprofessional boundaries. Grounded in safe practice and on contemporary evidence, this book also ensures that the health and wellbeing of the mother, baby and family remain at the forefront of care. Lists underpinning practices and guidelinesRationale, including indications and contraindications of when the skill should be undertakenProcedure: how the skill is performed, evaluated and documentedProfessional responsibilitiesKey practice pointsReferences and further reading

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