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Biocomposites and Hybrid Biomaterials of Calcium Orthophosphates with Polymers
by Sergey V. DorozhkinThis title gives an overview of composites and biocomposites. It discusses the history of CaPO4/ /polymer biocomposites and hybrid biomaterials, as well as analyzing the latest developments in the field. It also covers bioactivity and biodegradation of CaPO4-based biomaterials.
Biocomputing (Biocomputing #1)
by Panos M. Pardalos J. C. PrincipeIn the quest to understand and model the healthy or sick human body, re searchers and medical doctors are utilizing more and more quantitative tools and techniques. This trend is pushing the envelope of a new field we call Biomedical Computing, as an exciting frontier among signal processing, pattern recognition, optimization, nonlinear dynamics, computer science and biology, chemistry and medicine. A conference on Biocomputing was held during February 25-27, 2001 at the University of Florida. The conference was sponsored by the Center for Applied Optimization, the Computational Neuroengineering Center, the Biomedical En gineering Program (through a Whitaker Foundation grant), the Brain Institute, the School of Engineering, and the University of Florida Research & Graduate Programs. The conference provided a forum for researchers to discuss and present new directions in Biocomputing. The well-attended three days event was highlighted by the presence of top researchers in the field who presented their work in Biocomputing. This volume contains a selective collection of ref ereed papers based on talks presented at this conference. You will find seminal contributions in genomics, global optimization, computational neuroscience, FMRI, brain dynamics, epileptic seizure prediction and cancer diagnostics. We would like to take the opportunity to thank the sponsors, the authors of the papers, the anonymous referees, and Kluwer Academic Publishers for making the conference successful and the publication of this volume possible. Panos M. Pardalos and Jose C.
Bioconductor Case Studies (Use R!)
by Florian Hahne Wolfgang Huber Robert Gentleman Seth FalconBioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include: (1) import and preprocessing of data from various sources; (2) statistical modeling of differential gene expression; (3) biological metadata; (4) application of graphs and graph rendering; (5) machine learning for clustering and classification problems; (6) gene set enrichment analysis. Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table.
Bioconjugation: Methods and Protocols (Methods in Molecular Biology #2033)
by Sam Massa Nick DevoogdtThis book explores well-established and emerging conjugation strategies that are relevant for proteins used in the field of precision medicine, focusing on techniques that are suitable for antibodies, antibody-fragments such as Fabs, scFvs, or nanobodies, scaffold proteins such as FN3 or DARPin, peptides, or model proteins. Although centered on the development of bioconjugates rather than their application, most protocols also show the conjugation of the targeting vehicle to a diagnostic or therapeutic entity, with the end-product most often being an antibody-drug conjugate, an optical probe, a nanomedicine, or a radiopharmaceutical. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Bioconjugation: Methods and Protocols is an ideal guide for researchers looking toward precision medicine in order to expand the vital field of drug discovery.
Bioconjugation Protocols: Strategies and Methods (Methods in Molecular Biology #751)
by Sonny S. MarkContemporary approaches to the synthesis of chemically modified biomacromolecules (proteins, nucleic acids, lipids, and carbohydrates) not only require efficient means to control conjugation and the specific site of attachment of the conjugated moiety but also the effective use of recent developments in the fields of pharmaceutical chemistry, biomolecular/polymer engineering, and nanobiotechnology. In this second edition of Bioconjugation Protocols: Strategies and Methods, expert researchers update the classic methods and introduce valuable new approaches that go beyond basic conjugation techniques to include elements from advanced organic synthesis, molecular biology, surface biotechnology, materials science, and nanobioscience/engineering. These readily reproducible methods cover the preparation of biomolecular conjugates using a variety of labeling techniques and semisynthetic approaches. Additional chapters address the biofunctionalization of surface structures, including organic/inorganic thin films, as well as various types of nanostructures (magnetic nanoparticles, quantum dots, carbon nanotubes, and silicon nanowire devices). All the protocols follow the successful Methods in Molecular BiologyTM series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and highly practical, Bioconjugation Protocols: Strategies and Methods, Second Edition offers both novice and experienced researchers access to the broad array of techniques needed to carry out the semisynthesis of functional biomolecular reagents and/or the biofunctionalization of surfaces and structures of unique interest for a wide variety of applications, ranging from novel biomedical diagnostics to powerful new therapeutics to advanced biomaterials.
Biocontrol of Plant Diseases by Bacillus subtilis: Basic and Practical Applications (New Directions in Organic & Biological Chemistry)
by Makoto ShodaPlant diseases are a serious threat to food production. This unique volume provides the fundamental knowledge and practical use of B.subtilis as a promising biocontrol agent. In order to replace chemical pesticides, one possibility is microbial pesticides using safe microbes. Bacillus subtilis is one of several candidates. Screening of the bacterium, the application of plant tests, clarification of its suppressive mechanism to plant pathogens and engineering aspects of suppressive peptides production are presented here. The author illustrates how B. subtilis is far more advantageous than, for example, Pseudomonas in biocontrol and can be considered as an useful candidate. Features: Bacterium B. subtilis suppresses many plant pathogens and is a biocontrol agent to replace chemical pesticides The book presents the bacterium's suppressive mechanism to plant pathogens, and engineering aspects of suppressive peptides production Biological control of plant disease plays an important role in sustainable agricultural production practices and is expected to replace agricultural chemicals
Biocontrol of Plant Diseases by Bacillus subtilis: Basic and Practical Applications (New Directions in Organic & Biological Chemistry)
by Makoto ShodaPlant diseases are a serious threat to food production. This unique volume provides the fundamental knowledge and practical use of B.subtilis as a promising biocontrol agent. In order to replace chemical pesticides, one possibility is microbial pesticides using safe microbes. Bacillus subtilis is one of several candidates. Screening of the bacterium, the application of plant tests, clarification of its suppressive mechanism to plant pathogens and engineering aspects of suppressive peptides production are presented here. The author illustrates how B. subtilis is far more advantageous than, for example, Pseudomonas in biocontrol and can be considered as an useful candidate. Features: Bacterium B. subtilis suppresses many plant pathogens and is a biocontrol agent to replace chemical pesticides The book presents the bacterium's suppressive mechanism to plant pathogens, and engineering aspects of suppressive peptides production Biological control of plant disease plays an important role in sustainable agricultural production practices and is expected to replace agricultural chemicals
Biocybernetics and Biomedical Engineering – Current Trends and Challenges: Proceedings of the 22nd Polish Conference on Biocybernetics and Biomedical Engineering, Warsaw, Poland, May 19-21, 2021 (Lecture Notes in Networks and Systems #293)
by Dorota G. Pijanowska Krzysztof Zieliński Adam Liebert Janusz KacprzykThis book contains 13 chapters in which you can find various examples of the development of methods and/or systems supporting medical diagnostics and therapy, related to biomedical imaging, signal and image processing, biomechanics, biomaterials and artificial organs, modeling of biomedical systems, which, as the current research issues, were presented at the 22nd Polish BBE Conference held at the Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, in May 2021. Obviously, it is not easy to recommend an interdisciplinary book as it may seem inconsistent in some respects. This is the case here because it concerns the area of biocybernetics and biomedical engineering (BBE), which is not only an interdisciplinary but even multidisciplinary science. On the other hand, the scattered subject matter of the book is its advantage, as the book may be of interest to an advanced and wide range of readers and researchers representing both medical, biological and technical points of view.
Biodefence: Advanced Materials and Methods for Health Protection (NATO Science for Peace and Security Series A: Chemistry and Biology)
by Sergey Mikhalovsky and Abdukhakim KhajibaevThis book focuses on defence against biological warfare with an emphasis on applications of modern technologies and advanced materials in detection, health protection and medical treatment of the population. Specific topics include high-throughput sensitive detection methods, advanced nanostructured materials and techniques for external and internal protection of human health, as well as extracorporeal methods, adsorptive materials and bacteriophages decontaminating the human organism, and neutralising incorporated CBRN agents. The contributions describe recent developments in the field of biodefence aimed at protecting population against terrorism and terror related events. Broader approaches to reducing the impact of environmental pollution on human health and improving efficiency of medical treatment of patients with viral infections, poisoning and organ failure are also discussed.
Biodegradable Metals: From Concept to Applications (SpringerBriefs in Materials)
by Hendra HermawanThis book in the emerging research field of biomaterials covers biodegradable metals for biomedical applications. The book contains two main parts where each of them consists of three chapters. The first part introduces the readers to the field of metallic biomaterials, exposes the state of the art of biodegradable metals, and reveals its application for cardiovascular implants. Some fundamental aspects to give basic understanding on metals for further review on the degradable ones is covered in chapter one. The second chapter introduces the concept of biodegradable metals, it's state of the art and discuses a shifted paradigm from inert to bioactive, from corrosion resistant to corrodible metals. The third chapter focuses on the challenges and opportunities of using biodegradable metals for cardiovascular applications. The second part exposes an example of biodegradable metals from its concept to applications where a complete study on metallic biodegradable stent is detailed from materials design, development, testing till the implant fabrication. The forth chapter reveals new alloys development devoted for metallic biodegradable stent based on required criteria derrived from clinical needs and current nondegradable stents properties. Degradation of the alloys in simulated arterial conditions and its effect to cells are exposed in chapter five. The both chapters are concluded with a benchmarking of some more recent researches on materials development and testing for biodegradable stents. Chapter six reveals the tranformation process of the materials into stent prototypes where a standard process for making 316L stainless steel stents was followed. The book is completed by a perspective on the use of biodegradable metals for biomedical applications in the era of tissue engineering.
Biodegradable Poly (Lactic Acid): Synthesis, Modification, Processing and Applications
by Jie Ren"Biodegradable Poly (Lactic Acid): Synthesis, Modification, Processing and Applications" describes the preparation, modification, processing, and the research and applications of biodegradable poly (lactic acid), which belong to the biomedical and environment-friendly materials. Highly illustrated, the book introduces systematically the synthesis, physical and chemical modifications, and the latest developments of research and applications of poly (lactic acid) in biomedical materials.The book is intended for researchers and graduate students in the fields of materials science and engineering, polymer science and engineering, biomedicine, chemistry, environmental sciences, textile science and engineering, package materials, and so on.Dr. Jie Ren is a professor at the Institute of Nano and Bio-Polymeric Materials, School of Material Science and Engineering, Tongji University, Shanghai, China.
Biodegradable Polymer-Based Scaffolds for Bone Tissue Engineering (SpringerBriefs in Applied Sciences and Technology)
by naznin sultanaThis book addresses the principles, methods and applications of biodegradable polymer based scaffolds for bone tissue engineering. The general principle of bone tissue engineering is reviewed and the traditional and novel scaffolding materials, their properties and scaffold fabrication techniques are explored. By acting as temporary synthetic extracellular matrices for cell accommodation, proliferation, and differentiation, scaffolds play a pivotal role in tissue engineering. This book does not only provide the comprehensive summary of the current trends in scaffolding design but also presents the new trends and directions for scaffold development for the ever expanding tissue engineering applications.
Biodegradable Polymeric Nanocomposites: Advances in Biomedical Applications
by Dilip DepanHow Can Polymers Constructed From Living Organisms Help Eliminate the Disposal Issue? A unique category of materials called biodegradable polymers could help remedy a growing environmental concern. Biodegradable Polymeric Nanocomposites: Advances in Biomedical Applications considers the potential of biodegradable polymers for use in biomedical appl
Biodegradable Polymers and Their Emerging Applications (Materials Horizons: From Nature to Nanomaterials)
by Sampa Saha Chandrani SarkarBio-degradable polymers are rapidly emerging as a sustainable alternative to traditional petroleum-based plastics and polymers. However, the synthesis and processing of such polymers present unique challenges and opportunities. In this comprehensive volume, Dr. Saha and her team provide an in-depth exploration of the synthesis and processing of bio-degradable polymers and their emerging applications in various sectors from drug delivery to food packaging. Covering a wide range of topics, including synthesis, modification, processing techniques, and few of their advanced applications in emerging areas, this book provides a comprehensive overview of the field. The authors also delve into cutting-edge research on the synthesis, properties and applications of bio-degradable polymers in various fields, such as agricultural, food preservation, biomedical arena, energy storage and other advanced application areas. This volume is an essential resource for scientists, engineers, and policymakers interested in the future of sustainable materials. Whether you are a researcher looking to expand your knowledge of biodegradable polymer synthesis and processing or a policymaker interested in the potential of biodegradable polymers to reduce our reliance on fossil fuels, this book is an invaluable guide to the field.
Biodegradation of Pesticides
by Fumio Matsumura and C. R. Krishna MurtiWhen first developed, chlorinated pesticides such as DDT, dieldrin, and mirex were received with open arms, quickly becoming popular as effective, economic agents against pests. But evidence began to mount that residues of these chemicals remained in the environment, not breaking down, often appearing in plants and animals. By the late seventies many pesticides had achieved a terrible notoriety and were subsequently banned in a number of countries. Of tremendous concern, then, is the persistence of pesticides in the environment. The major thrust of research and development in the area of pesticides has properly been the creation of substances that are both effective and degradable. Yet in order to successfully promote the use of biodegradable pesticides, one must fully understand the mechanism of degradation, and it is to this vital subject that we address ourselves in the present volume. According to the Biodegradation Task Force, Safety of Chemicals Com mittee, Brussels (1978), biodegradation may be defined as the molecular degradation of an organic substance resulting from the complex action of living organisms. A substance is said to be biodegraded to an environmentally acceptable extent when environmentally undesirable properties are lost. Loss of some characteristic function or property of substance by biodegradation may be referred to as biological transformation.
Biodemography of Aging: Determinants of Healthy Life Span and Longevity (The Springer Series on Demographic Methods and Population Analysis #40)
by Anatoliy I. Yashin Eric Stallard Kenneth C. LandThis volume is a critical exposition of the data and analyses from a full decade of rigorous research into how age-related changes at the individual level, along with other factors, contribute to morbidity, disability and mortality risks at the broader population level. After summarizing the state of our knowledge in the field, individual chapters offer enlightening discussion on a range of key topics such as age trajectory analysis in select and general populations, incidence/age patterns of major chronic illnesses, and indices of cumulative deficits and their use in characterizing and understanding the detailed properties of individual aging.The book features comprehensive statistical analyses of unique longitudinal data sets including the unique resource of the Framingham Heart Study, with its more than 60 years of follow-up. Culminating in penetrating conclusions about the insights gained from the work involved, this book adds much to our understanding of the links between aging and human health.
The Biodemography of Human Reproduction and Fertility
by Hans-Peter Kohler Joseph Lee RodgersThe book that you hold in your hands is the second in a series. The two titles in the series are the following: Genetic Influences on Human Fertility and Sexuality: Theoretical and Empirical Contributions from the Biological and Behavior Sciences Edited by Joseph Lee Rodgers, David C. Rowe, & Warren B. Miller Published by Kluwer Academic Press, 2000 The Biodemography of Human Reproduction and Fertility Edited by Joseph Lee Rodgers & Hans-Peter Kohler Published by Kluwer Academic Press, 2002 The series has published chapters by researchers who study human fertility, from a particular perspective: Biodemography. We welcome your interest and participation in this developing subfield. Or, perhaps, biodemography may be better referred to as a "superfield. " Because biodemography so naturally crosses interdisciplinary boundaries, and because its application draws together researchers from disparate disciplines, it may well be more appropriate to consider that biodemography subsumes a number of other disciplines, rather than the other way around. In this preface, we will describe our own efforts and those of many others to promote and develop the study of human fertility, using methods, models, and theories from both biological and demographic domains. In December, 1997, 25 participants from three different countries gathered in Tucson, Arizona for a small conference with the title "Genetic Influences on Fertility-Related Processes. " That conference represented a fascinating blending of research from two apparently separate domains.
Biodental Engineering II
by R. M. Natal Jorge J. C. Reis Campos Sónia M. Santos Joao Manuel R. S. TavaresDentistry is a branch of medicine with its own peculiarities and very diverse areas of action, which means that it can be considered as an interdisciplinary field. BIODENTAL ENGINEERING II contains the full papers presented at the 2nd International Conference on Biodental Engineering (BioDENTAL 2012, Porto, Portugal, 7-8 December 2012). The contrib
Biodental Engineering III
by J. C. Reis Campos Sónia M. Santos João Manuel R. S. Tavares Mário A. P. Vaz R. M. Natal JorgeDentistry is a branch of medicine with its own peculiarities and very diverse areas of action, which means that it can be considered as an interdisciplinary field. Currently the use of new techniques and technologies receives much attention. Biodental Engineering III contains contributions from 13 countries, which were presented at BIODENTAL 2014,
Biodental Engineering IV: Proceedings of the IV International Conference on Biodental Engineering, June 21-23, 2016, Porto, Portugal
by João Manuel R.S. Tavares R.M. Natal Jorge J.C. Reis Campos Mário A.P. Vaz Sónia M. SantosSince dentistry is a branch of medicine with its own peculiarities and very diverse areas of action, it can be considered as an interdisciplinary field. BIODENTAL ENGINEERING IV contains the full papers presented at the 4th International Conference on Biodental Engineering (BIODENTAL 2016, Vila Nova de Famalicão, Portugal, 21—23 June 2016), and covers the use of new techniques and technologies in dentistry. The contributions provide a comprehensive coverage of the state-of-the art in this area, and addresses the following topics: • Aesthetics• Bioengineering• Biomaterials• Biomechanical disorders• Biomedical devices• Computational bio- imaging and visualization• Computational methods• Dental medicine• Experimental mechanics• Signal processing and analysis• Implantology• Minimally invasive devices and techniques• Orthodontics• Prosthesis and orthosis• Simulation• Software development• Telemedicine• Tissue engineering• Virtual reality BIODENTAL ENGINEERING IV will be of interest to academics and professionals involved or interested in dentistry, biomechanical disorders, numerical simulation, orthodontics, implantology, aesthetics, dental medicine, medical devices and medical imaging.
Biodental Engineering IV: Proceedings of the IV International Conference on Biodental Engineering, June 21-23, 2016, Porto, Portugal
by Sónia M. Santos R. M. Natal Jorge J. C. Reis Campos Mário A. P. Vaz Joao Manuel R. S. TavaresSince dentistry is a branch of medicine with its own peculiarities and very diverse areas of action, it can be considered as an interdisciplinary field. BIODENTAL ENGINEERING IV contains the full papers presented at the 4th International Conference on Biodental Engineering (BIODENTAL 2016, Vila Nova de Famalicão, Portugal, 21—23 June 2016), and covers the use of new techniques and technologies in dentistry. The contributions provide a comprehensive coverage of the state-of-the art in this area, and addresses the following topics: • Aesthetics• Bioengineering• Biomaterials• Biomechanical disorders• Biomedical devices• Computational bio- imaging and visualization• Computational methods• Dental medicine• Experimental mechanics• Signal processing and analysis• Implantology• Minimally invasive devices and techniques• Orthodontics• Prosthesis and orthosis• Simulation• Software development• Telemedicine• Tissue engineering• Virtual reality BIODENTAL ENGINEERING IV will be of interest to academics and professionals involved or interested in dentistry, biomechanical disorders, numerical simulation, orthodontics, implantology, aesthetics, dental medicine, medical devices and medical imaging.
Biodental Engineering V: Proceedings of the 5th International Conference on Biodental Engineering (BIODENTAL 2018), June 22-23, 2018, Porto, Portugal
by Jorge Belinha R. M. Natal Jorge J. C. Reis Campos Mário A. P. Vaz João Manuel R. S. TavaresDentistry is a branch of medicine with its own particularities and very different fields of action, and is generally regarded as an interdisciplinary field. The use of new technologies is currently the main driving force for the series of international conferences on Biodental Engineering (BIODENTAL). BIODENTAL ENGINEERING V contains the full papers presented at the 5th International Conference on Biodental Engineering (BIODENTAL 2018, Porto, Portugal, 22-23 June 2018). The conference had two workshops, one of them dealing with computational imaging combined with finite element method, the other dealing with bone tissue remodelling models. Additionally, the conference had three special sessions and sixty contributed presentations. The topics discussed in BIODENTAL ENGINEERING V include: AestheticsBioengineeringBiomaterialsBiomechanical disordersBiomedical devicesComputational bio- imaging and visualizationComputational methodsDental medicineExperimental mechanicsSignal processing and analysisImplantologyMinimally invasive devices and techniquesOrthodonticsProsthesis and orthosisSimulationSoftware developmentTelemedicineTissue engineeringVirtual reality The purpose of the series of BIODENTAL Conferences on Biodental Engineering, initiated in 2009, is to perpetuate knowledge on bioengineering applied to dentistry, by promoting a comprehensive forum for discussion on recent advances in related fields in order to identify potential collaboration between researchers and end-users from different sciences.
Biodentine™: Properties and Clinical Applications
by Imad AboutThis book is a comprehensive guide to BiodentineTM, an innovative biocompatible and bioactive material based on pure tricalcium silicate that can permanently replace dentin and can also serve as a temporary enamel substitute. Although BiodentineTM has been widely used across the world for the past decade, this is the first book to be devoted to its properties, interactions with the soft and hard tissues, and its multiple clinical applications. The coverage encompasses applications in primary and permanent teeth, in specialties as diverse as restorative dentistry, endodontics, paediatric dentistry, dental traumatology, and prosthetic dentistry. BiodentineTM application both in vital pulp therapy and endodontic procedures is illustrated and clinical step by step protocols are provided. The book provides a detailed update on BiodentineTM use to preserve the pulp vitality in direct/indirect pulp capping, pulpotomy and irreversible pulpitis treatment. It also details BiodentineTM use for non-vital teeth treatment in indications such as root/furcation perforation repair, apexification as well as in regenerative endodontic procedures.BiodentineTM: Properties and Clinical Applications will be a rich source of guidance and information for all dentists as well as dental students and academics.
Biodiesel from Flowering Plants
by Samuel Paul Raj Pravin Raj Solomon Baskar ThangarajThis book offers an exhaustive coverage of process modifications in biodiesel production from oil drawn from 84 oleaginous plant species occurring in all parts of the world, thereby enlisting the scope and potential of many new and non-conventionally obscure plant sources. Biodiesel, now prepared from major vegetable oils, has become a compulsion to offset the dwindling reserve of petro-diesel, which naturally intrudes into the cooking oil demand. This has necessitated search for new sources. The book consolidates the biodiesel production from oils being extracted from conventional plants and also from a plethora of new and non-conventional plants along with their habit and habitats, history of biodiesel’s invention, explanation on species-wise biodiesel process variables, catalytic inclusions, global standards, fuel properties varying with species, blending benefits, cost effectiveness, shelf life, ignition characteristics, fuel consumption and engine performances with eco-friendly exhaust. This book is of immense use to teachers, researchers, scientists of climatology and carbon footprint, energy consultants, fuel chemists, students of agriculture and forestry, automobile engineering, industrial chemistry, environmental sciences and policy makers or anyone who wishes to scale up the biodiesel industry.
Biodiversity and Evolution of Parasitic Life in the Southern Ocean (Parasitology Research Monographs #9)
by Sven Klimpel Thomas Kuhn Heinz MehlhornThe Southern Oceans including Antarctic regions are peculiar and very sensitive water biotopes, where animal life and species interrelations are only poorly investigated. Especially the influence of parasites on their host species needs intensive consideration in times of global warming and worldwide pollution. Both factors may influence the finely balanced interrelationships between parasites and endangered hosts especially in specialized regions such as Antarctica. Before this background the present book offers a broad spectrum of important parasite-host interrelations in times of ecosystem changes written by experienced and renown international specialists.