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Urticaria and Angioedema
by Torsten Zuberbier Clive Grattan Marcus MaurerUrticaria is one of the most common diseases encountered in dermatology. The fleeting nature of wheals often makes a first diagnosis by both patients and physicians seem easy. The disease itself is of a highly complex nature, with a variety of clinical manifestations ranging from pinpoint sized wheals to extensive angioedema. Further complexities include the diversity of possible eliciting and aggravating factors, the many different clinical subtypes and the therapeutic responsiveness.This second, extensively revised edition includes the indications listed in the most recent international guidelines, provides a practical, comprehensive review of all clinical aspects and causes, and addresses the diagnosis and therapy of different types of urticaria. Specific chapters are devoted to classification, aetiopathogenesis, patient reported outcomes, acute urticaria, chronic urticaria and its comorbidities, angioedema without weals, inducible urticarias, special populations including children, treatment with antihistamines and omalizumab, other interventions and looking ahead to new therapies. This new edition is a must read for dermatologists, allergists, pediatricians and practitioners of all disciplines who want their patients to benefit from cutting-edge diagnostics and treatments.
Urticaria and Angioedema
by Torsten Zuberbier Clive E. H. Grattan Marcus MaurerUrticaria is one of the most common diseases in dermatology and allergy. Unlike many other diseases, the ? eeting nature of the wheals makes ? rst diagnosis by both patients and phy- cians in many cases easy. However, this only refers to the ordinary wheals. The disease itself is highly complex in nature, with variety of clinical manifestations ranging from pinpoi- sized wheals to extensive angiodema. Complexity is also seen in the diversity of possible eliciting factors, the many different clinical subtypes and the therapeutic responsiveness. Only in recent years has a better understanding of the diversity in the different subtypes led to new classi? cations and new evidence-based guidelines for diagnostics and mana- ment of the disease. While mast cells are in the center of most urticaria reactions, it is now clearly understood that the responsible mediators are not only limited to histamines. The current book appears in a series of books by Springer. In 1986, the ? rst monograph was edited by Professor Henz née Chanewsky. Since then, two updates of the book have appeared in the German language with Professor Henz as ? rst editor and T. Zuberbier, J. Grabbe, and E. Monroe as the co-editors of the most recent English version, published in 1998. All these books have been written as a joint effort of Professor Henz together with her team at the Department of Dermatology at the Virchow Clinic, Humboldt University, Berlin.
Function and Control of the Spx-Family of Proteins Within the Bacterial Stress Response (SpringerBriefs in Microbiology)
by Peter ZuberThis SpringerBrief on Spx reviews the investigations that led to the discovery of Spx and its orthologs and ties together the results of various studies that have explored the function and control of spx in Gram-positive organisms. Spx of Bacillus subtilis has been extensively studied, but very little has been published about it. This book incorporates a number of studies that have been conducted in other Gram positive bacteria, which examined the role of Spx orthologs in stress response, bacterial development and virulence. The book contains an overview that will introduce the protein and its orthologous forms, its association with RNA polymerase, the species of Gram-positive bacteria in which it is found, and the conditions in which it is abundant and active. Spx is a member of a large group of proteins belonging to the ArsC/Spx protein family, so the review touches upon the bioinformatic support for the protein family composition and its meaning with regard to protein structure/function.
Breast Cancer, a Heterogeneous Disease Entity: The Very Early Stages
by Zsuzsanna Kahán and Tibor TotThe volume raises attention to the need of a completely new approach to breast cancer based on the knowledge collected on early breast cancer in the past two decades. The chapters are contributed by experts of all the fields participating in the clinical research and care of breast cancer. The practical importance of such a book is underlined by the increasing number of breast cancer cases, and also the increasing proportion of early stage-cases. The ultimate goal of the book is to point to the heterogeneous nature of the disease which is more striking and has more importance in care at the very early stages than at the more advanced stages. The book recommends the utilization of all the information provided by multimodality imaging and special pathological methods, a new classification system and therapeutic guidelines since early breast cancers should not be treated based on experience obtained with palpable tumors. No similar book has been yet released to the market. The book is written for all the members of the team participating in the diagnosis and treatment of breast cancer (radiologists, pathologists, surgeons, clinical and radiation oncologists), but may be useful for medical students and residents too. The chapters are illustrated with didactic pictures, and special emphasis is given to provide a peep into the practice of the special procedures for the careful examination and individualized therapy of each case.
Leisure, Health and Well-Being: A Holistic Approach (Leisure Studies in a Global Era)
by Zsuzsanna Benkő, Ishwar Modi and Klára TarkóThis book explores health and leisure as a holistic phenomenon with individual and social dimensions. Contributors to this edited volume explore the physical, mental, emotional, sexual and social aspects of health and leisure as well as the influence of moral and religious principles. The connections between the individual and the social structure, social integration, the social division of labor, and the natural environment are also analysed.The volume studies this relationship from a range of disciplinary backgrounds, including sociology, psychology, psychiatry, medical sciences, sport sciences, education, policy making, and from both national and international perspectives. As such, the collection will be of interest to scholars and students across a range of disciplines, including Leisure Studies, Health Studies, Health Promotion, Psychology and Mental Health, Sociology and Sport Studies.
Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices
by Zsolt Peter Nagy, Alex C. Varghese and Ashok AgarwalThe Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is a unique, accessible title that provides a complete review of the most well-established and current diagnostic and treatment techniques comprising in vitro fertilization. Throughout the chapters, a uniform structure is employed, including a brief abstract, a keyword glossary, a step-by-step protocol of the laboratory procedures, several pages of expert commentary, key issues of clinical concern, and a list of references. The result is a readily accessible, high quality reference guide for reproductive endocrinologists, urologists, embryologists, biologists and research scientists. The Manual also offers an excellent description of novel procedures that will likely be employed in the near future. An indispensable resource for physicians and basic scientists, the Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is an invaluable reference and addition to the literature.
Klinische Elektroenzephalographie
by Stephan Zschocke Hans-Christian HansenDie Autoren beschreiben in dem Band die physiologischen und pathophysiologischen Grundlagen der Elektroenzephalographie (EEG) und machen die Technologie Schritt für Schritt verständlich: Behandelt werden die EEG-Potenziale in ihren verschiedenen Formen sowie der Einsatz der EEG in der Intensivmedizin. Das Werk hilft Ärzten, brauchbare Kurven zu gewinnen, Befunde zu verstehen und zu interpretieren, aber auch Fehler zu vermeiden. Die 3., aktualisierte und überarbeitete Auflage enthält ein neues Kapitel über die EEG in der Neuropädiatrie.
Klinische Elektroenzephalographie
by Stephan Zschocke Hans-Christian HansenDie Autoren beschreiben in dem Band die physiologischen und pathophysiologischen Grundlagen der Elektroenzephalographie (EEG) und machen die Technologie Schritt für Schritt verständlich: Behandelt werden die EEG-Potenziale in ihren verschiedenen Formen sowie der Einsatz der EEG in der Intensivmedizin. Das Werk hilft Ärzten, brauchbare Kurven zu gewinnen, Befunde zu verstehen und zu interpretieren, aber auch Fehler zu vermeiden. Die 3., aktualisierte und überarbeitete Auflage enthält ein neues Kapitel über die EEG in der Neuropädiatrie.
Basic Mechanisms of the EEG (Brain Dynamics)
by Zschocke SpeckmannThis volume is based on selected and updated papers from the symposium on "Basic Mechanisms of the EEG," which was held under the sponsor ship of the German EEG Society in Hamburg on September 28-29, 1990. The intention of this symposium was to relate recent experimental, clini cal, and neuropathological data on the basic mechanism that underlie the EEG. Although we know much about these mechanisms, there is still much more to be learned. The symposium was partly the continuation of an earlier symposium on "Origin of Cerebral Field Potentials" held in 1979 in Munster under the leadership of one of the present editors (E. -J. Speckmann) and H. Caspers. The present work combines new experimental and clinical results with state-of-the-art reports giving excellent general views. The first chapter presents a historical survey of the roots of current developments in neu rophysiology. It seems that in the near future we may decipher the EEG, which we have considered up to now somewhat as a cryptogram (chap ter 2). After chapter 3-a chapter concerned with more general points of the generation of cortical field potentials-chapters 4, 5, and 6 deal with several aspects and models of interactions and rhythms of cortical neurons. The role of glial cells in cortical electrical field generation is considered in chapter 7. Chapter 8 emphasizes the significance of brain metabolism.
JIMD Reports - Case and Research Reports, Volume 13 (JIMD Reports #13)
by Johannes Zschocke K. Michael Gibson Garry Brown Eva Morava Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports - Volume 12 (JIMD Reports #12)
by Johannes Zschocke K. Michael Gibson Garry Brown Eva Morava Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports, Volume 14 (JIMD Reports #14)
by Johannes Zschocke K. Michael Gibson Garry Brown Eva Morava Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports, Volume 15 (JIMD Reports #15)
by Johannes Zschocke K. Michael Gibson Garry Brown Eva Morava Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports Volume 16 (JIMD Reports #16)
by Johannes Zschocke K. Michael Gibson Garry Brown Eva Morava Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports, Volume 17 (JIMD Reports #17)
by Johannes Zschocke K. Michael Gibson Garry Brown Eva Morava Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports, Volume 18 (JIMD Reports #18)
by Johannes Zschocke Matthias Baumgartner Eva Morava Marc Patterson Shamima Rahman Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports, Volume 19 (JIMD Reports #19)
by Johannes Zschocke Matthias Baumgartner Eva Morava Marc Patterson Shamima Rahman Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports, Volume 20 (JIMD Reports #20)
by Johannes Zschocke Matthias Baumgartner Eva Morava Marc Patterson Shamima Rahman Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports, Volume 21 (JIMD Reports #21)
by Johannes Zschocke Matthias Baumgartner Eva Morava Marc Patterson Shamima Rahman Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports, Volume 22 (JIMD Reports #22)
by Johannes Zschocke Matthias Baumgartner Eva Morava Marc Patterson Shamima Rahman Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports, Volume 23 (JIMD Reports #23)
by Johannes Zschocke Matthias Baumgartner Eva Morava Marc Patterson Shamima Rahman Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
JIMD Reports, Volume 24 (JIMD Reports #24)
by Johannes Zschocke Matthias Baumgartner Eva Morava Marc Patterson Shamima Rahman Verena PetersJIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
Neurophysiological Aspects of Color Vision in Primates: Comparative Studies on Simian Retinal Ganglion Cells and the Human Visual System (Studies of Brain Function #9)
by E. Zrenner"To explain all nature is too difficult a task for anyone man or even for anyone age. Tis much better to do a little with certainty, and leave the rest for others that come after you, than to explain all things ... " Sir Isaac Newton (1642-1727) This book describes and discusses some new aspects of col or vision in primates which have emerged from a series of experiments conducted over the past 8 years both on single ganglion cells in monkey retina and on the visually evoked cortical potential in man: corresponding psychophysical mechanisms of human perception will be considered as well. An attempt will be made to better understand the basic mechanisms of color vision using a more comprehensive approach which takes into account new mechanisms found in single cells and relates them to those found valid for the entire visual system. The processing of color signals was followed up from the retina to the visual cortex and to the percepq.tal centers, as far as the available techniques permitted.
