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Mountain Lions of the Black Hills: History and Ecology
by Jonathan A. JenksMountain lions, sometimes called pumas or cougars, were once spread throughout the United States, occupying all 48 of the contiguous states. By the 1960s, though, they were almost extinct in central and eastern North America. In Mountain Lions of the Black Hills, Dr. Jonathan A. Jenks, who, along with his team of graduate students, has tracked over 200 of these fascinating predators, tells the complex story of the big cats;€™ lives in the northern Great Plains.Jenks reports on mountain lion population dynamics, diet, nutrition, diseases, behavior, and genetics. He explores the impact of a changing prey base on population growth and decline, movements within and away from the region, and hunting on the species; discusses interactions between the cats and livestock; and examines local people;€™s evolving perceptions of mountain lions. Throughout, Jenks explores how we can balance conservation techniques with the needs of humans.Providing a unique look into how a large, secretive predator recolonized an isolated region of North America, Mountain Lions of the Black Hills is required reading for wildlife professionals. A captivating text for anyone struck by the wild majesty of these big cats, this book provides invaluable data upon which to make sound management decisions in the Great Plains and beyond.
Mountains Without Handrails: Reflections on the National Parks
by Joseph L. SaxBeloved by academic and general readers alike, Mountains Without Handrails, Joseph L. Sax’s thought-provoking treatise on America’s national parks, remains as relevant today as when first published in 1980. Focusing on the long-standing and bitter battles over recreational use of our parklands, Sax proposes a novel scheme for the protection and management of America's national parks. Drawing upon still controversial disputes—Yosemite National Park, the Colorado River in the Grand Canyon, and the Disney plan for California's Mineral King Valley—Sax boldly unites the rich and diverse tradition of nature writing into a coherent thesis that speaks directly to the dilemma of the parks. In a new foreword, environmental law scholar Holly Doremus articulates this book’s enduring importance and reflects on what Sax, her former teacher, might have thought about the encroachment of technology into natural spaces, the impact of social media, and growing threats from climate change. At this moment of great uncertainty for the national parks, Mountains Without Handrails should be read (and re-read) by anyone with a stake in America’s natural spaces.
Mouse Embryogenesis: Methods and Protocols (Methods in Molecular Biology #1752)
by Paul Delgado-OlguinThis volume explores protocols for identifying mutant mice and characterizing parts of their anatomical, functional, cellular, and molecular phenotypes. The chapters in this book look at anatomical and functional phenotyping using quantitative imaging, isolation of specific embryonic cell types for cell culture, analysis of gene expression, and how to define chromatin structure. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and authoritative, Mouse Embryogenesis: Methods and Protocols is a valuable resource for experimentalists interested in discovering new aspects of embryogenesis control, organ function, and the origin of disease.
Mouse Oocyte Development: Methods and Protocols (Methods in Molecular Biology #1818)
by Marie-Hélène Verlhac Marie-Emilie TerretThis book details methods on various aspects of the very final stages of mouse oocyte development. Chapters guide the reader through in vitro growth of follicles, production of a fully-grown competent mouse oocyte, meiosis resumption, analysis of spindle assembly and chromosome segregation, analysis of the oocyte and early embryo transcriptome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mouse Oocyte Development: Methods and Protocols aims to help scientists with the set up both live and fix experiments required to study the process of oocyte meiotic maturation.
Mouse Retinal Phenotyping: Methods and Protocols (Methods in Molecular Biology #1753)
by Naoyuki TanimotoThe aim of this volume is to provide a wide range of techniques and aspects of mouse retinal phenotyping and characterization. Chapters guide readers through morphological and functional properties of the mouse retina and techniques for the analysis of outer to mid-retina and mid- to inner retina. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Mouse Retinal Phenotyping: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Mr Lemoncello's Great Library Race (Mr. Lemoncello's Library #3)
by Chris GrabensteinEveryone's favourite game maker, Mr Lemoncello, is testing out his new FABULOUS FACT-FINDING FRENZY game! Kyle must compete in a great race - by bicycle, bookmobile, and even Mr. Lemoncello's corporate banana jet! - to find fascinating facts about famous Americans.But then a few surprising 'facts' surface about Mr Lemoncello . . . Could Kyle's hero be a fraud? Kyle and the other kids will have to dig deep to find out the truth before it's GAME OVER for Mr Lemoncello . . . !
Mudflat Ecology (Aquatic Ecology Series #7)
by Peter G. BeningerIntertidal mudflats are distinct, highly-productive marine habitats which provide important ecosystem services to the land-sea interface. In contrast to other marine habitats, and despite a large body of primary scientific literature, no comprehensive synthesis exists, such that the scattered knowledge base lacks an integrated conceptual framework. We attempt to provide this synthesis by pulling together and contextualizing the different disciplines, tools, and approaches used in the study of intertidal mudflats. The editor pays particular attention to relationships between the various components of the synthesis, both at the conceptual and the operational levels, validating these relationships through close interaction with the various authors.
Multi-agent Optimization: Cetraro, Italy 2014 (Lecture Notes in Mathematics #2224)
by Angelia Nedić Jong-Shi Pang Gesualdo Scutari Ying Sun Francisco FacchineiThis book contains three well-written research tutorials that inform the graduate reader about the forefront of current research in multi-agent optimization. These tutorials cover topics that have not yet found their way in standard books and offer the reader the unique opportunity to be guided by major researchers in the respective fields. Multi-agent optimization, lying at the intersection of classical optimization, game theory, and variational inequality theory, is at the forefront of modern optimization and has recently undergone a dramatic development. It seems timely to provide an overview that describes in detail ongoing research and important trends. This book concentrates on Distributed Optimization over Networks; Differential Variational Inequalities; and Advanced Decomposition Algorithms for Multi-agent Systems. This book will appeal to both mathematicians and mathematically oriented engineers and will be the source of inspiration for PhD students and researchers.
Multi-axis Substructure Testing System for Hybrid Simulation (SpringerBriefs in Applied Sciences and Technology)
by Riadh Al-Mahaidi M. Javad Hashemi Robin Kalfat Graeme Burnett John WilsonThis book describes the multi-axis substructure testing (MAST) system, a simulator developed at Swinburne University of Technology, Australia, which provides state-of-the-art technology for large-scale hybrid testing of structures under realistic scenarios depicting extreme events. The book also demonstrates the responses of physical specimens while they serve as part of the virtual computer model of the full structure subjected to extreme dynamic forces. Experimental studies using the MAST system are expected to enhance design and construction methods and significantly improve the repair and retrofitting of structures endangered by natural disasters and man-made hazards, providing a direct benefit to society by improving public safety and the resilience of the built environment. An additional benefit is increased sustainability in the form of reduced direct and indirect economic losses and social and environmental impacts in the face of extreme events. This book will be of interest to researchers and advanced practitioners in the fields of structural earthquake engineering, geotechnical earthquake engineering, engineering seismology, and experimental dynamics, including seismic qualification.
Multi-dimensional Approaches Towards New Technology: Insights on Innovation, Patents and Competition
by Ashish Bharadwaj Vishwas H. Devaiah Indranath GuptaThis open access edited book captures the complexities and conflicts arising at the interface of intellectual property rights (IPR) and competition law. To do so, it discusses four specific themes: (a) policies governing functioning of standard setting organizations (SSOs), transparency and incentivising future innovation; (b) issue of royalties for standard essential patents (SEPs) and related disputes; (c) due process principles, procedural fairness and best practices in competition law; and (d) coherence of patent policies and consonance with competition law to support innovation in new technologies. Many countries have formulated policies and re-oriented their economies to foster technological innovation as it is seen as a major source of economic growth. At the same time, there have been tensions between patent laws and competition laws, despite the fact that both are intended to enhance consumer welfare. In this regard, licensing of SEPs has been debated extensively, although in most instances, innovators and implementers successfully negotiate licensing of SEPs. However, there have been instances where disagreements on royalty base and royalty rates, terms of licensing, bundling of patents in licenses, pooling of licenses have arisen, and this has resulted in a surge of litigation in various jurisdictions and also drawn the attention of competition/anti-trust regulators. Further, a lingering lack of consensus among scholars, industry experts and regulators regarding solutions and techniques that are apposite in these matters across jurisdictions has added to the confusion. This book looks at the processes adopted by the competition/anti-trust regulators to apply the principles of due process and procedural fairness in investigating abuse of dominance cases against innovators.
Multi-Disciplinary Digital Signal Processing: A Functional Approach Using Matlab
by E. S. GopiThis book provides a comprehensive overview of digital signal processing for a multi-disciplinary audience. It posits that though the theory involved in digital signal processing stems from electrical, electronics, communication, and control engineering, the topic has use in other disciplinary areas like chemical, mechanical, civil, computer science, and management. This book is written about digital signal processing in such a way that it is suitable for a wide ranging audience. Readers should be able to get a grasp of the field, understand the concepts easily, and apply as needed in their own fields. It covers sampling and reconstruction of signals; infinite impulse response filter; finite impulse response filter; multi rate signal processing; statistical signal processing; and applications in multidisciplinary domains. The book takes a functional approach and all techniques are illustrated using Matlab.
Multi-layer Pavement System under Blast Load (Springer Tracts in Civil Engineering)
by Jun Wu Hao Wu Hong Wei Tan Soon Hoe ChewThis book proposes the concept of a multi-layer pavement system to fulfill the blast resistance requirement for pavement design. It also presents a damage pattern chart for multi-layer pavement design and rapid repair after blast load. Such a multi-layer system consists of three layers including asphalt concrete (AC) reinforced with Geogrid (GST) at the top, a high-strength concrete (HSC) layer in the middle, and engineered cementitious composites (ECC) at the bottom. A series of large-scale laboratory impact tests were carried out to prove the usefulness of this concept and show its advantages over other conventional pavement system. Furthermore, field blast tests were conducted to show the actual behavior of this multi-layer pavement system subjected to blast load under real-world conditions.
Multi-Modality Imaging: Applications And Computational Techniques
by Mauren Abreu de Souza Humberto Remigio Gamba Helio PedriniThis book presents different approaches on multi-modality imaging with a focus on biomedical applications. Medical imaging can be divided into two categories: functional (related to physiological body measurements) and anatomical (structural) imaging modalities.In particular, this book covers imaging combinations coming from the usual popular modalities (such as the anatomical modalities, e.g. X-ray, CT and MRI), and it also includes some promising and new imaging modalities that are still being developed and improved (such as infrared thermography (IRT) and photoplethysmography imaging (PPGI)), implying potential approaches for innovative biomedical applications.Moreover, this book includes a variety of tools on computer vision, imaging processing, and computer graphics, which led to the generation and visualization of 3D models, making the most recent advances in this area possible. This is an ideal book for students and biomedical engineering researchers covering the biomedical imaging field.
Multi-Modality Neuroimaging Study on Neurobiological Mechanisms of Acupuncture
by Jie TianThis book introduces essential advances in acupuncture studies using multi-modality neuroimaging, which provides insights into how specific brain networks are involved in acupuncture effects in humans. Stimulating different acupoints to treat various clinical conditions is usually accompanied by multi-dimensional physiological as well as psychological responses, which are regulated by the central nervous system. The book addresses disease-specific neural correlates and acupuncture-targeted regulatory encoding in the brain, and explains the temporal-spatial encoding in brain networks to clarify the acupuncture mechanisms. By highlighting the targeting mechanisms of typical indications of acupuncture, this book provides a scientific explanation for acupuncture therapy.
Multi-shell Polyhedral Clusters (Carbon Materials: Chemistry and Physics #10)
by Mircea Vasile DiudeaThis volume presents new methodologies and rationalizes existing methods that are used in the design of multi-shell polyhedral clusters. The author describes how the methods used are extended from 2D-operations on maps to 3D (and higher dimensional) Euclidean space. A variety of structures is designed and described in detail and classified giving rise to an atlas of multi-shell nanostructures. The book therefore sheds a new light on the field of crystal and quasicrystal structures, an important part of nanoscience and nanotechnology. The author goes on to show how the recently established methods are used for building complex multi-shell nanostructures and how this completes the existing information in the field. The atlas of such structures is completed with atomic coordinates (included as supplementary material). The content of this book gives a useful insight into structure elucidation and suggests new material synthesis.
Multicomponent Reactions: Synthesis of Bioactive Heterocycles
by K. L. Ameta Anshu DandiaThis timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.
Multicomponent Reactions: Synthesis of Bioactive Heterocycles
by K. L. Ameta Anshu DandiaThis timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.
Multidisciplinary Approaches to Forensic Archaeology: Topics Discussed During The European Meetings On Forensic Archaeology (emfa) (Soil Forensics Ser.)
by Pier Matteo Barone W. J. GroenThis book will present the most advanced research on forensic archaeology presented during the annual European meetings in the last 3 years. Thanks to the broad nature of the chapters presented, this book will show not only different approaches and different crime scenes around Europe, but also how every single European law enforcement has faced forensic investigations. This book shows forensic archaeology as practiced in this legal context, emerging and solidifying in many European countries, differing in some respects because of differences in legal systems but ultimately sharing common grounds. Differently from similar books, this will be not only a collection of research and case studies in which forensic practitioners demonstrate the extent and complexity of the various aspects of forensic archaeology, but also it will show the necessity of co-operation as a condition for any work in forensic archaeology among scientists of different disciplines and law enforcers.
Multidisciplinary Care of the Head and Neck Cancer Patient (Cancer Treatment and Research #174)
by Ellie Maghami Allen S. HoThis book identifies key treatment challenges and unique care considerations in patients with head and neck cancers, providing a comprehensive guide to patient management that illustrates the critical importance of a multidisciplinary approach in achieving optimal oncological, functional, and survival outcomes. It covers all relevant specialties, including dental and oral medicine, medical oncology, radiation oncology, surgical oncology, and reconstructive surgery. It highlights the vital role played by ancillary head and neck cancer services, such as speech and swallowing therapy, occupational and physical therapy, and nutritional therapy in offering essential physical and psychological support from the time of diagnosis onward. The closing chapters address post-treatment issues, including those relating to survivorship, surveillance, and end-of-life care. Multidisciplinary care is perhaps even more important for patients with head and neck cancers than for other cancer patients, and in addressing all its aspects this book is invaluable for a wide range of practitioners.
Multidisciplinary Medico-Legal Death Investigation: Role of Consultants
by Lakshmanan Sathyavagiswaran Christopher B. RogersMultidisciplinary Medico-legal Death Investigation: Role of Consultants is the only book in the field that focuses on the role consultants have in medical examiner/coroner offices. The book provides a multidisciplinary view on the topic by including specialized fields, such as anesthesiology, surgery, radiology, including CT scan, pediatrics, cardiology-electrophysiology, cardiac pathology, forensic anthropology and odontology, firearms examination, firearms, eye pathology and psychiatry/psychology. Coverage also includes chapters on specialized topics, including high profile cases, the media, business continuity planning, envenomations, the importance of quality assurance and peer review, and quality assurance in a medico-legal death investigation office. This one-of-a-kind resource is ideal for those in the medico-legal death investigation field and professionals in the criminal and civil justice system.Covers many fields, including anesthesiology, surgery, and radiology, including CT scan, pediatrics, cardiology-electrophysiology, cardiac pathology, forensic anthropology and odontology, firearms examination, and more Includes contributions by world-renowned specialistsPresents comprehensive case studies and examples of consultation reports
Multidisciplinary Teleconsultation in Developing Countries (TELe-Health)
by Michelangelo Bartolo Fabio FerrariThis book presents a replicable model of multidisciplinary teleconsultation, designed and set up by Global Health Telemedicine, that offers very significant health benefits in remote and rural areas of developing countries. The model is based on experiences gained in sub-Saharan Africa while training and cooperating with local health professionals within the DREAM program, managed by the Community of Sant’Egidio. This program has to date treated almost 300,000 patients across many countries and has provided health education and disease prevention training to tens of millions. It originated in the context of the fight against AIDS but has been extended to encompass other pathologies and to exploit the capabilities of new telemedicine technologies that allow multispecialist teleconsultation (hence the acronym now represents “Disease Relief through Excellent and Advanced Means”). In addition to thorough description of the program, readers will find reflections and analysis on logistical, technical, sociological, and epidemiological issues. The book is divided into thematic chapters with easy-to-understand graphics. It will be a readily accessible source of information for professionals in international cooperation and global health students and professionals.
Multifaceted Protocol in Biotechnology
by Azura Amid Sarina Sulaiman Dzun Noraini Jimat Nor Fadhillah AzminThis edited work presents useful methods in experimenting in the area of Bioprocessing and Biotechnology. The four sections cover the area of Bioprocess, Whole Cells & Isolated Biocatalyst, Characterization of Biochemical Products and Cell Isolation & Culture. Its enable researchers to choose a suitable method and plan their experiments in details. The main focus of this book is to provide step by step method to young researchers, especially in the new research areas. Among the latest areas are the isolation of novel strain or enzyme by metagenomic approaches and taming procedure in the laboratories, development of novel, the cheap and non-toxic catalyst for biodiesel production, and production of micro-fibrillated cellulose. An updated method for well-known areas such as immobilization technology, biosensor, and polymerization was also presented. The book also covers in-silico methods such as MATLAB platform to ease researchers. Not to forget, the method in animal and plant culture is also discussed in detail.The book is written by chapter authors with much expertise in their fields. They have published multiple articles in the index listed journals.The topic of this book is particularly relevant to young researchers who are struggling to fine-tune their research and do not want to waste their time in optimizing the experiment set up.
Multifunctional Gold Nanostars for Cancer Theranostics (Springer Theses)
by Yang LiuThis thesis presents the development of theranostic gold nanostars (GNS) for multimodality cancer imaging and therapy. Furthermore, it demonstrates that a novel two-pronged treatment, combining immune-checkpoint inhibition and GNS-mediated photothermal nanotherapy, can not only eradicate primary treated tumors but also trigger immune responses to treat distant untreated tumors in a mouse animal model. Cancer has become a significant threat to human health with more than eight million deaths each year, and novel methods for cancer management to improve patients’ overall survival are urgently needed. The developed multifunctional GNS nanoprobe with tip-enhanced plasmonics in the near-infrared region can be combined with (1) surface-enhanced Raman spectroscopy (SERS), (2) two-photon photoluminescence (TPL), (3) X-ray computed tomography (CT), (4) magnetic resonance imaging (MRI), (5) positron emission tomography (PET), and (6) photothermal therapy (PTT) for cancer imaging and treatment. The ability of the GNS nanoprobe to detect submillimeter intracranial brain tumors was demonstrated using PET scan – a superior non-invasive imaging modality – in a mouse animal model. In addition, delayed rechallenge with repeated cancer cell injection in cured mice did not lead to new tumor formation, indicating generation of a memorized immune response to cancer. The biocompatible gold nanostars with superior capabilities for cancer imaging and treatment have great potential for translational medicine applications.
Multifunctional Nanocomposites for Energy and Environmental Applications
by Zhanhu Guo Yuan Chen Na Luna LuFocusing on real applications of nanocomposites and nanotechnologies for sustainable development, this book shows how nanocomposites can help to solve energy and environmental problems, including a broad overview of energy-related applications and a unique selection of environmental topics. Clearly structured, the first part covers such energy-related applications as lithium ion batteries, solar cells, catalysis, thermoelectric waste heat harvesting and water splitting, while the second part provides unique perspectives on environmental fields, including nuclear waste management and carbon dioxide capture and storage. The result is a successful combination of fundamentals for newcomers to the field and the latest results for experienced scientists, engineers, and industry researchers.
Multifunctional Nanocomposites for Energy and Environmental Applications
by Zhanhu Guo Yuan Chen Na Luna LuFocusing on real applications of nanocomposites and nanotechnologies for sustainable development, this book shows how nanocomposites can help to solve energy and environmental problems, including a broad overview of energy-related applications and a unique selection of environmental topics. Clearly structured, the first part covers such energy-related applications as lithium ion batteries, solar cells, catalysis, thermoelectric waste heat harvesting and water splitting, while the second part provides unique perspectives on environmental fields, including nuclear waste management and carbon dioxide capture and storage. The result is a successful combination of fundamentals for newcomers to the field and the latest results for experienced scientists, engineers, and industry researchers.