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Interventional Magnetic Resonance Imaging (Medical Radiology)

The idea of using the enormous potential of magnetic resonance imaging (MRI) not only for diagnostic but also for interventional purposes may seem obvious, but it took major efforts by engineers, physicists, and clinicians to come up with dedicated interventional techniques and scanners, and improvements are still ongoing. Since the inception of interventional MRI in the mid-1990s, the numbers of settings, techniques, and clinical applications have increased dramatically. This state of the art book covers all aspects of interventional MRI. The more technical contributions offer an overview of the fundamental ideas and concepts and present the available instrumentation. The richly illustrated clinical contributions, ranging from MRI-guided biopsies to completely MRI-controlled therapies in various body regions, provide detailed information on established and emerging applications and identify future trends and challenges.

Molecular Virology

Aphasie: Wege aus dem Sprachdschungel (Praxiswissen Logopädie)

Der Band vermittelt in einer ausgewogenen Mischung aus Fachwissen und Praxis-Know-how ein umfassendes Verständnis von Krankheitsbild und Therapie der Aphasie: von den neurologischen Grundlagen, den Reorganisationsmechanismen, Sprachverarbeitungsmodellen über Diagnostik und Klassifikationssysteme bis hin zur Planung und Durchführung der Therapie. Der Band eignet sich als Nachschlagewerk ebenso wie als Leitfaden und bietet Übungen zu allen Aspekten der Therapie-Praxis.

Bifunctional Molecular Catalysis (Topics in Organometallic Chemistry #37)

Masakatsu Shibasaki, Motomu Kanai, Shigeki Matsunaga, and Naoya Kumagai: Multimetallic Multifunctional Catalysts for Asymmetric Reactions.- Takao Ikariya: Bifunctional transition metal-based molecular catalysts for asymmetric syntheses.- Chidambaram Gunanathan and David Milstein: Bond Activation by Metal-Ligand Cooperation: Design of ”Green” Catalytic Reactions Based on Aromatization-Dearomatization of Pincer Complexes.- Madeleine C. Warner, Charles P. Casey, and Jan-E. Bäckvall: Shvo’s Catalyst in Hydrogen Transfer Reactions.- Noritaka Mizuno, Keigo Kamata, and Kazuya Yamaguchi: Liquid-Phase Selective Oxidation by Multimetallic Active Sites of Polyoxometalate-Based Molecular Catalysts.- Pingfan Li and Hisashi Yamamoto: Bifunctional Acid Catalysts for Organic Synthesis.- Jun-ichi Ito, Hisao Nishiyama: Bifunctional Phebox Complexes for Asymmetric Catalysis.

Smart Cities: Deutsche Hochtechnologie für die Stadt der Zukunft - Aufgaben und Chancen (acatech BEZIEHT POSITION)

Seit 2007 wohnt erstmals mehr als die Hälfte der Menschheit in Ballungsräumen, im Jahr 2030 werden es 60 Prozent sein. Mit der weltweiten Urbanisierung wächst der Bedarf an vernetzten Technologien. Deutschland hat gute Chancen, sich als führender Anbieter solcher „Smarter Technologien“ zu etablieren – wenn dafür die Rahmenbedingungen geschaffen werden. In dem Band erläutern Experten aus Wissenschaft und Wirtschaft, wie als Antwort auf den Bedarf an integrierten Lösungen neue Wertschöpfungsmöglichkeiten erschlossen werden können.

Akzeptanz von Technik und Infrastrukturen: Anmerkungen zu einem aktuellen gesellschaftlichen Problem (acatech BEZIEHT POSITION)

Kaum ein anderes Thema beschäftigt die Öffentlichkeit im Zusammenhang mit neuen Technologien so sehr wie deren Akzeptanz. Gab es bisher vor allem Widerstand gegen Kernenergie oder Gentechnik, ist heute auch der Ausbau der regenerativen Energien betroffen, etwa beim Bau von Netzen. In der Stellungnahme identifizieren Experten aus Wissenschaft und Wirtschaft Muster der gegenwärtigen Akzeptanz-Diskussion, betrachten deren Auswirkungen auf das Innovationsklima und liefern Handlungsempfehlungen zur Verbesserung des gesellschaftlichen Dialogs.

Navier-Stokes-Fourier Equations: A Rational Asymptotic Modelling Point of View

This research monograph deals with a modeling theory of the system of Navier-Stokes-Fourier equations for a Newtonian fluid governing a compressible viscous and heat conducting flows. The main objective is threefold. First , to 'deconstruct' this Navier-Stokes-Fourier system in order to unify the puzzle of the various partial simplified approximate models used in Newtonian Classical Fluid Dynamics and this, first facet, have obviously a challenging approach and a very important pedagogic impact on the university education. The second facet of the main objective is to outline a rational consistent asymptotic/mathematical theory of the of fluid flows modeling on the basis of a typical Navier-Stokes-Fourier initial and boundary value problem. The third facet is devoted to an illustration of our rational asymptotic/mathematical modeling theory for various technological and geophysical stiff problems from: aerodynamics, thermal and thermocapillary convections and also meteofluid dynamics.

Multiphase Flow Dynamics 4: Turbulence, Gas Adsorption and Release, Diesel Fuel Properties

The present Volume 4 of the successful monograh package “Multiphase Flow Dynamics”is devoted to selected Chapters of the multiphase fluid dynamics that are important for practical applications but did not find place in the previous volumes. The state of the art of the turbulence modeling in multiphase flows is presented. As introduction, some basics of the single phase boundary layer theory including some important scales and flow oscillation characteristics in pipes and rod bundles are presented. Then the scales characterizing the dispersed flow systems are presented. The description of the turbulence is provided at different level of complexity: simple algebraic models for eddy viscosity, simple algebraic models based on the Boussinesq hypothesis, modification of the boundary layer share due to modification of the bulk turbulence, modification of the boundary layer share due to nucleate boiling. The role of the following forces on the mathematical description of turbulent flows is discussed: the lift force, the lubrication force in the wall boundary layer, and the dispersion force. A pragmatic generalization of the k-eps models for continuous velocity field is proposed containing flows in large volumes and flows in porous structures. A Methods of how to derive source and sinks terms for multiphase k-eps models is presented. A set of 13 single- and two phase benchmarks for verification of k-eps models in system computer codes are provided and reproduced with the IVA computer code as an example of the application of the theory. This methodology is intended to help other engineers and scientists to introduce this technology step-by-step in their own engineering practice.In many practical application gases are solved in liquids under given conditions, released under other conditions and therefore affecting technical processes for good of for bad. Useful information on the solubility of oxygen, nitrogen, hydrogen and carbon dioxide in water under large interval of pressures and temperatures is collected, and appropriate mathematical approximation functions are provided. In addition methods for the computation of the diffusion coefficients are described. With this information solution and dissolution dynamics in multiphase fluid flows can be analyzed. For this purpose the non-equilibrium absorption and release on bubble, droplet and film surfaces under different conditions is mathematically described. A systematic set of internally consistent state equations for diesel fuel gas and liquid valid in broad range of changing pressure and temperature is provided.This new second edition includes various updates, extensions, improvements and corrections. In many practical application gases are solved in liquids under given conditions, released under other conditions and therefore affecting technical processes for good of for bad. Useful information on the solubility of oxygen, nitrogen, hydrogen and carbon dioxide in water under large interval of pressures and temperatures is collected, and appropriate mathematical approximation functions are provided. In addition methods for the computation of the diffusion coefficients are described. With this information solution and dissolution dynamics in multiphase fluid flows can be analyzed. For this purpose the non-equilibrium absorption and release on bubble, droplet and film surfaces under different conditions is mathematically described. A systematic set of internally consistent state equations for diesel fuel gas and liquid valid in broad range of changing pressure and temperature is provided.This new second edition includes various updates, extensions, improvements and corrections.

Evolutionary Biology – Concepts, Biodiversity, Macroevolution and Genome Evolution

The annual Evolutionary Biology Meetings in Marseilles serve to gather leading scientists, promote the exchange of ideas and encourage the formation of international collaborations.This book contains the most essential contributions presented at the 14th Evolutionary Biology Meeting, which took place in September 2010. It comprises 19 chapters organized according to the following categories:· Evolutionary Biology Concepts· Biodiversity and Evolution· Macroevolution· Genome EvolutionOffering an up-to-date overview of recent results in the field of evolutionary biology, this book is an invaluable source of information for scientists, teachers and advanced students.

Is this Cell a Human Being?: Exploring the Status of Embryos, Stem Cells and Human-Animal Hybrids

The central question of this book is whether or not particular cell entities of human origin ought to be considered human beings. The answer is crucial for making moral decisions for or against research and experimentation. Experts in the field discuss the production of embryonic-like pluripotent stem cells by altered nuclear transfer, parthenogenesis and reprogramming of adult somatic cells. They thoroughly analyse the biological and moral status of different cell entities, such as human stem cells, embryos and human-animal hybrid embryos, and make a decisive step towards establishing final criteria for what constitutes a human being. The topic is challenging in nature and of broad interest to all those concerned with current bioethical thought on embryonic human life and its implications for society.

Advanced Protocols for Animal Transgenesis: An ISTT Manual (Springer Protocols Handbooks)

This laboratory manual, published in cooperation with the International Society for Transgenic Technology (ISTT), provides almost all current methods that can be applied to the creation and analysis of genetically modified animals. The chapters have been contributed by leading scientists who are actively using the technology in their laboratories. Based on their first-hand experience the authors also provide helpful notes and troubleshooting sections. Topics range from standard techniques, such as pronuclear microinjection of DNA, to more sophisticated and modern methods, such as the derivation and establishment of embryonic stem (ES) cell lines, with defined inhibitors in cell culture medium. In addition, related topics with relevance to the field are addressed, including global web-based resources, legal issues, colony management, shipment of mice and embryos, and the three R’s: refinement, reduction and replacement.

Chromium -VI Reagents: Synthetic Applications (SpringerBriefs in Molecular Science)

Chromic acid and chromium oxide are the two versatile Cr(VI) oxidants known to organic chemists for decades. The introduction of the Core's reagent , viz: pyridinium chlorochromate, in 1975 followed by the publications on several Cr(VI) oxidizing agents containing the -onium chromates and halochromates in the last three decades have very much changed the chemistry of oxidations with Chromium VI. Several of these new reagents have been shown to be mild so that they can be handled easily and the reacton products may also be controlled. Some of them are highly selective oxidants for positions like allylic hydroxylic group, etc., and some other are highly regioselective. The information on more than 36 such reagents reported in various internationally reputed journals spanning about 280 references have been collected and provided in this book in such a manner that it will be very useful for professionals, researchers, teachers and graduate students working in organic synthesis.

Numerical Methods for the Life Scientist: Binding and Enzyme Kinetics Calculated with GNU Octave and MATLAB

Enzyme kinetics, binding kinetics and pharmacological dose-response curves are currently analyzed by a few standard methods. Some of these, like Michaelis-Menten enzyme kinetics, use plausible approximations, others, like Hill equations for dose-response curves, are outdated. Calculating realistic reaction schemes requires numerical mathematical routines which usually are not covered in the curricula of life science. This textbook will give a step-by-step introduction to numerical solutions of non-linear and differential equations. It will be accompanied with a set of programs to calculate any reaction scheme on any personal computer. Typical examples from analytical biochemistry and pharmacology can be used as versatile templates. When a reaction scheme is applied for data fitting, the resulting parameters may not be unique. Correlation of parameters will be discussed and simplification strategies will be offered.

Coding and Decoding of Calcium Signals in Plants (Signaling and Communication in Plants)

Plants cannot move away from their environments. As a result, all plants that have survived to date have evolved sophisticated signaling mechanisms that allow them to perceive, respond, and adapt to constantly changing environmental conditions. Among the many cellular processes that respond to environmental changes, elevation of calcium levels is by far the most universal messenger that matches primary signals to cellular responses. Yet it remains unclear how calcium, a simple cation, translates so many different signals into distinct responses - how is the “specificity” of signal-response coupling encoded within the calcium changes?This book will attempt to answer this question by describing the cellular and molecular mechanisms underlying the coding and decoding of calcium signals in plant cells.

Probiotics: Biology, Genetics and Health Aspects (Microbiology Monographs #21)

Probiotic microorganisms have a long history of use, and their health benefits for hosts are well documented. This Microbiology Monographs volume provides an overview of the current knowledge and applications of probiotics. Reviews cover the biology and probiotic potential of the thoroughly studied prokaryotic genera Lactobacillus and Bifidobacterium, several eukaryotic microorganisms, probiotic strain characterization, and the analytical methods (such as FISH, microarray, and high throughput sequencing) required for their study. Further chapters describe the positive effects of probiotics on malabsorption disorders such as diarrhea and lactose intolerance, and document the clinical evidence of benefits in treating allergies and lung emphysema, and in dermatological applications. Also addresses are topics such as genetically engineered strains, new carriers for probiotics, protection techniques, challenges of health claims, safety aspects, and future market trends.

Modern Mathematical Tools and Techniques in Capturing Complexity (Understanding Complex Systems)

Real-life problems are often quite complicated in form and nature and, for centuries, many different mathematical concepts, ideas and tools have been developed to formulate these problems theoretically and then to solve them either exactly or approximately.This book aims to gather a collection of papers dealing with several different problems arising from many disciplines and some modern mathematical approaches to handle them. In this respect, the book offers a wide overview on many of the current trends in Mathematics as valuable formal techniques in capturing and exploiting the complexity involved in real-world situations. Several researchers, colleagues, friends and students of Professor María Luisa Menéndez have contributed to this volume to pay tribute to her and to recognize the diverse contributions she had made to the fields of Mathematics and Statistics and to the profession in general. She had a sweet and strong personality, and instilled great values and work ethics in her students through her dedication to teaching and research. Even though the academic community lost her prematurely, she would continue to provide inspiration to many students and researchers worldwide through her published work.

Elegance and Enigma: The Quantum Interviews (The Frontiers Collection)

Quantum mechanics is one of mankind's most remarkable intellectual achievements. Stunningly successful and elegant, it challenges our deepest intuitions about the world. In this book, seventeen physicists and philosophers, all deeply concerned with understanding quantum mechanics, reply to Schlosshauer's penetrating questions about the central issues. They grant us an intimate look at their radically different ways of making sense of the theory's strangeness. What is quantum mechanics about? What is it telling us about nature? Can quantum information or new experiments help lift the fog? And where are we headed next? Everyone interested in the contemporary but often longstanding conundrums of quantum theory, whether lay reader or expert, will find much food for thought in these pages. A wealth of personal reflections and anecdotes guarantee an engaging read. Participants: Guido Bacciagaluppi, Caslav Brukner, Jeffrey Bub, Arthur Fine, Christopher Fuchs, GianCarlo Ghirardi, Shelly Goldstein, Daniel Greenberger, Lucien Hardy, Anthony Leggett, Tim Maudlin, David Mermin, Lee Smolin, Antony Valentini, David Wallace, Anton Zeilinger, and Wojciech Zurek.

Neurotraining: Therapeutische Arbeit im kognitiven Bereich mit hirngeschädigten Erwachsenen

Das anspruchsvolle und praxiserprobte Therapieprogramm Neurotraining nach Verena Schweizer setzt gezielt dort an, wo es not tut: Konzentration, Lernen und Gedächtnis, Planen und Handeln.Viele Jahre Erfahrung und ständige Weiterentwicklung anhand der Arbeit mit den Patienten fließen in dieses ergotherapeutische Therapieprogramm ein und machen es zu einem essenziellen Praxisbuch für Therapeuten.Die theoretische Einführung in das Neurotraining liefert die GrundlagenPraktische Übungen in verständlicher Sprache setzen die Theorie realitätsnah um Alle fertig aufbereiteten Befundungs-, Arbeits- und Übungsbögen als Kopiervorlagen

Advanced Sliding Mode Control for Mechanical Systems: Design, Analysis and MATLAB Simulation

"Advanced Sliding Mode Control for Mechanical Systems: Design, Analysis and MATLAB Simulation" takes readers through the basic concepts, covering the most recent research in sliding mode control. The book is written from the perspective of practical engineering and examines numerous classical sliding mode controllers, including continuous time sliding mode control, discrete time sliding mode control, fuzzy sliding mode control, neural sliding mode control, backstepping sliding mode control, dynamic sliding mode control, sliding mode control based on observer, terminal sliding mode control, sliding mode control for robot manipulators, and sliding mode control for aircraft. This book is intended for engineers and researchers working in the field of control. Dr. Jinkun Liu works at Beijing University of Aeronautics and Astronautics and Dr. Xinhua Wang works at the National University of Singapore.

Reactivity Tuning in Oligosaccharide Assembly (Topics in Current Chemistry #301)

Armed–Disarmed Effects in Carbohydrate Chemistry: History, Synthetic and Mechanistic Studies, by Bert Fraser-Reid and J. Cristóbal López *A Survey of Ley’s Reactivity Tuning in Oligosaccharide Synthesis, by Ana M. Gómez * “Active–Latent” Thioglycosyl Donors and Acceptors in Oligosaccharide Syntheses, by Tze Chieh Shiao and René Roy * Effect of Electron-Withdrawing Protecting Groups at Remote Positions of Donors on Glycosylation Stereochemistry, by Kwan Soo Kim and Dae-Hwan Suk * Influence of Protecting Groups on the Reactivity and Selectivity of Glycosylation: Chemistry of the 4,6-O-Benzylidene Protected Mannopyranosyl Donors and Related Species, by Sylvain Aubry, Kaname Sasaki, Indrajeet Sharma and David Crich * Superarmed and Superdisarmed Building Blocks in Expeditious Oligosaccharide Synthesis, by Hemali D. Premathilake and Alexei V. Demchenko*Programmable One-Pot Glycosylation, by Chung -Yi Wu and Chi -Huey Wong *Uronic Acids in Oligosaccharide and Glycoconjugate Synthesis, by Jeroen D. C. Codée, Alphert E. Christina, Marthe T. C. Walvoort, Herman S. Overkleeft and Gijsbert A. van der Marel

Advances in Elastomers I: Blends and Interpenetrating Networks (Advanced Structured Materials)

This is the first volume of a two-volume work which summarizes in an edited format and in a fairly comprehensive manner many of the recent technical research accomplishments in the area of Elastomers. “Advances in Elastomers” discusses the various attempts reported on solving these problems from the point of view of the chemistry and the structure of elastomers, highlighting the drawbacks and advantages of each method. It summarize the importance of elastomers and their multiphase systems in human life and industry, and covers all the topics related to recent advances in elastomers, their blends, IPNs, composites and nanocomposites.This first volume focuses on advances on the blends and interpenetrating networks (IPNs) of elastomers.

Advances in Elastomers II: Composites and Nanocomposites (Advanced Structured Materials)

This is the second volume of a two-volume work which summarizes in an edited format and in a fairly comprehensive manner many of the recent technical research accomplishments in the area of Elastomers. “Advances in Elastomers” discusses the various attempts reported on solving these problems from the point of view of the chemistry and the structure of elastomers, highlighting the drawbacks and advantages of each method. It summarize the importance of elastomers and their multiphase systems in human life and industry, and covers all the topics related to recent advances in elastomers, their blends, IPNs, composites and nanocomposites.This second volume is deals with composites and nanocomposites of elastomers.

Advances in Natural Polymers: Composites and Nanocomposites (Advanced Structured Materials #18)

The book summarizes in a comprehensive manner many of the recent technical research accomplishments in the area of natural polymers. It discusses the various attempts reporting on solving this problem from the point of view of the chemistry and the structure of natural polymers, highlighting the drawbacks and advantages of each method and proposal. Based on considerations of structure - property relations, it is possible to obtain fibers with improved strength by making use of their nanostructures and/or mesophase properties of natural polymers. The book is a unique book with contributions from the experts of the biomaterial area research. it covers all topics related to natural biomaterials such as natural rubber, cellulose, chitin, starch, hemicellulose, lignin, alginates, soy protein, casein and their bionanocomposites and applications. This book is a useful reference for scientists, academicians, research scholars and biotechnologists.

Disorder and Strain-Induced Complexity in Functional Materials (Springer Series in Materials Science #148)

This book brings together an emerging consensus on our understanding of the complex functional materials including ferroics, perovskites, multiferroics, CMR and high-temperature superconductors. The common theme is the existence of many competing ground states and frustration as a collusion of spin, charge, orbital and lattice degrees of freedom in the presence of disorder and (both dipolar and elastic) long-range forces. An important consequence of the complex unit cell and the competing interactions is that the emergent materials properties are very sensitive to external fields thus rendering these materials with highly desirable, technologically important applications enabled by cross-response.

Alternative Energy Sources (Green Energy and Technology)

Alternative Energy Sources is designed to give the reader, a clear view of the role each form of alternative energy may play in supplying the energy needs of the human society in the near future (20-50 years).The two first chapters on "energy demand and supply" and "environmental effects," set the tone as to why alternative energy is essential for the future. The third chapter gives the laws of energy conversion processes, as well as the limitations of converting one energy form to another. The section on exergy gives a quantitative background on the capability/potential of each energy source to produce power. The fourth, fifth and sixth chapters are expositions of fission and fusion nuclear energy, the power plants that may produce power from these sources and the issues that will frame the public debate on nuclear energy. The following five chapters include descriptions of the most common renewable energy sources (wind, solar, geothermal, biomass, hydroelectric) some of the less common sources (e.g. tidal and wave energy). The emphasis of these chapters will be on the global potential of each source, the engineering/technical systems that are used in harnessing the potential of each source, the technological developments that will contribute to wider utilization of the sources and environmental effects associated with their wider use. The last three chapters are: "energy storage," which will become an important issue if renewable energy sources are used widely.The fourteen chapters in the book have been chosen so that one may fit a semester University course around this book. At the end of every chapter, there are 10-20 problems and 1-3 suggestions of semester projects that may be assigned to students for further research.