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Oxford Textbook of Clinical Nephrology (Oxford Textbook)

This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

Challenging Concepts in Neurosurgery: Cases with Expert Commentary (Challenging Cases)

Part of the Challenging Concepts in series, this book is a case-based guide to challenging clinical scenarios in neurosurgery covering the major sub-speciality areas of oncology, vascular neurosurgery, brain and spine trauma, paediatrics, spinal degenerative disease, peripheral and cranial nerves, functional neurosurgery and infection. Specific cases are examined with consideration of clinical presentation, diagnostics, and surgical principles, with a summary of evidence from the neurosurgical literature highlighting areas of interest and controversy. This book serves as a useful and engaging resource for consultants and trainees in neurosurgery as well as in the disciplines of neurology, maxillofacial surgery, spinal surgery and neuro-oncology.

The Maudsley Handbook of Practical Psychiatry

The Maudsley Handbook of Practical Psychiatry has long served trainees in psychiatry, presenting them with practical and essential advice. This new edition of the orange book provides guidance on the psychiatric and neuropsychiatric examination and interviewing of adults and childrennot just as a central skill, but as the basis for reaching a diagnosis, formulation and defining a treatment plan. It covers special interview situations, such as dealing with specific patient reactions, and other special problems, for example, conducting a complicated assessment in cases of self-harm. The book concludes with important legal issues and is supported by helpful appendices for ready-reference. As with previous editions, this sixth edition has been revised and rewritten with the full and active involvement of a group of consultant psychiatrists and trainees, making it a highly relevant and practical handbook for all psychiatrists whether learning or refreshing their skills.

The Maudsley Handbook of Practical Psychiatry

The Maudsley Handbook of Practical Psychiatry has long served trainees in psychiatry, presenting them with practical and essential advice. This new edition of the orange book provides guidance on the psychiatric and neuropsychiatric examination and interviewing of adults and childrennot just as a central skill, but as the basis for reaching a diagnosis, formulation and defining a treatment plan. It covers special interview situations, such as dealing with specific patient reactions, and other special problems, for example, conducting a complicated assessment in cases of self-harm. The book concludes with important legal issues and is supported by helpful appendices for ready-reference. As with previous editions, this sixth edition has been revised and rewritten with the full and active involvement of a group of consultant psychiatrists and trainees, making it a highly relevant and practical handbook for all psychiatrists whether learning or refreshing their skills.

Treatment-Resistant Mood Disorders (Oxford Psychiatry Library)

Treatment-resistant major depression and bipolar disorder are highly prevalent and disabling conditions associated with substantial morbidity and mortality. The assessment and management of refractory patients with mood disorders is a major clinical challenge for mental health providers. Part of the Oxford Psychiatry Library (OPL) series, this pocketbook provides a concise view of the current definitions, assessment and evidence-based management of treatment-resistant mood disorders and reviews novel therapeutic targets for mood disorders, which may enhance the therapeutic armamentarium of clinicians in the near future. The pocketbook serves as a useful guide for mental health practitioners, including psychiatrists, clinical psychologists, trainees, and interested primary care physicians.

Family-making: Contemporary Ethical Challenges

Neuroprogression and Staging in Bipolar Disorder

After the original proposals of staging for psychotic disorders developed by McGorry and colleagues, a few systems have been put forward specifically for people with bipolar disorder. There is now consistent evidence that, at least for a significant portion of people with this disease, clinical course and outcome are not as benign as initially described. The evidence thus far points to relevant differences between early and late stages of bipolar disorders in the clinical course of illness, neurobiology and systemic pathology. These differences all suggest that staging is a viable addition to clinical care in bipolar disorder. Neuroprogression and Staging in Bipolar Disorder provides a comprehensive summary of the current state of the evidence regarding the use of staging systems in bipolar disorder. Edited by the leading researchers in the field, the book systematically covers the theoretical basis for staging, comparisons between different proposals, neurobiological underpinnings, the current evidence-base, limitations and future directions, and clinical implications and recommendations for practice. The book provides a solid and in-depth outline and thus to influence research and practice in the field of bipolar disorder.

Neuroprogression and Staging in Bipolar Disorder

After the original proposals of staging for psychotic disorders developed by McGorry and colleagues, a few systems have been put forward specifically for people with bipolar disorder. There is now consistent evidence that, at least for a significant portion of people with this disease, clinical course and outcome are not as benign as initially described. The evidence thus far points to relevant differences between early and late stages of bipolar disorders in the clinical course of illness, neurobiology and systemic pathology. These differences all suggest that staging is a viable addition to clinical care in bipolar disorder. Neuroprogression and Staging in Bipolar Disorder provides a comprehensive summary of the current state of the evidence regarding the use of staging systems in bipolar disorder. Edited by the leading researchers in the field, the book systematically covers the theoretical basis for staging, comparisons between different proposals, neurobiological underpinnings, the current evidence-base, limitations and future directions, and clinical implications and recommendations for practice. The book provides a solid and in-depth outline and thus to influence research and practice in the field of bipolar disorder.

Pickard's Guide to Minimally Invasive Operative Dentistry

An ideal introduction to the theory and practical aspects of conservative dentistry, the tenth edition of Pickards' Guide to Minimally Invasive Operative Dentistry is a must-have text for all dental students, new graduates and oral healthcare professionals alike. Written in an easy to understand and concise style, the authors introduce the essentials of dental disease before outlining how to collect patient information clinically in order to detect, diagnose, plan and deliver care. Exploring key topics such as disease prevention and control, the principles of minimally invasive operative dentistry, contemporary restorative materials and procedures, this completely up-to-date revised edition integrates a thorough academic grounding for degree examination with an essential preparation for clinical practice for the whole oral healthcare team. Illustrated with step-by-step colour photos, common clinical procedures are clearly set out and labelled for beginners to learn. The tenth edition has been updated to reflect the latest evidence based guidelines for preventitative management and there is a focus on maintaining existing restorations and follow up/long term care.

Textbook of Post-ICU Medicine: The Legacy of Critical Care

Surviving critical illness is not always the happy ending we imagine for patients. Many ICU survivors suffer from a range of long-lasting physical and psychological issues such end stage renal disease, congestive heart failure, cognitive impairment, neuromuscular weakness, and depression or anxiety, which affect their overall quality of life and ability to lead productive lives. This lingering burden or 'legacy' of critical illness is now recognized as a major public health issue, with major efforts underway to understand how it can be prevented, mitigated, or treated. The Textbook of Post-ICU Medicine: The Legacy of Critical Care discusses the science of the recovery process and the innovative treatment regimens which are helping ICU survivors regain function as they heal following trauma or disease. Describing the major clinical syndromes affecting ICU survivors, the book delineates established or postulated biological mechanisms of the post-acute recovery process, and discusses strategies for treatment and rehabilitation to promote recovery in the ICU and in the long term. The chapters are written by an interdisciplinary panel of leading clinicians and researchers working in the field. The book serves as a unique reference for general practitioners, internists and nurses caring for long term ICU survivors as well as specialists in intensive care medicine, neurology, psychiatry, and rehabilitation medicine.

Regional Anaesthesia: A Pocket Guide

Regional Anaesthesia: A Pocket Guide is an essential companion to the practice of regional anaesthesia for consultants and trainees in the specialty. Filled with practical advice and carefully designed for ease of use, this book is the helpful aid to practice that anaesthetists have been waiting for. The book covers all the major blocks by anatomical region, from the head and upper extremities, to the lower extremities and para-axial region. The technique for each procedure is prefaced by information on its difficulty, indications, contraindications, and potential side-effects. Every procedure is also accompanied by a range of high-quality clinical photographs and anatomical drawings that demonstrate the importance of applying anatomical knowledge in practical anaesthetic procedures. Regional anaesthesia is a fast-moving specialty, and this book takes into account recent advances in ultrasound-guided techniques with a strong focus on real-time observation of needle placement. Landmark-placed blocks have are also covered for clinicians without access to ultrasound technology. Regional Anaesthesia: A Pocket Guide is a unique compilation of anaesthetic techniques that offers support and guidance for any trainee or specialist in their every day practice.

Schizophrenia (Oxford Psychiatry Library)

Part of the Oxford Psychiatry Library of pocketbooks, this user-friendly and practical guide will outline the diagnosis, evaluation and treatment of patients with schizophrenia. Co-authored by two global experts on the management of patients with psychosis, this pocketbook will serve as a useful guide for psychiatrists, trainees, psychiatric specialist nurses, and interested general practitioners. Schizophrenia is one of the most disabling mental illnesses and is also highly prevalent, occurring in approximately 1% of the population and affecting both men and women equally. The disorder has a typical onset of between 15 and 35 years of age and is characterised by impairments in reality, most commonly hallucinations and delusions. It is a highly complex condition and is often confused with other mental disorders such as bipolar disorder. This new edition will cover new DSM-5 diagnostic criteria and to reflect new data and include new longitudinal studies on psychiatric and medical co-morbidity, Genetic and environmental factors, new drug therapies, adherence and the role of depots, new advances in psychosocial therapies (CBT,ACT, & cognitive remediation) and includes an updated and expanded appendix.

Schizophrenia (Oxford Psychiatry Library)

Part of the Oxford Psychiatry Library of pocketbooks, this user-friendly and practical guide will outline the diagnosis, evaluation and treatment of patients with schizophrenia. Co-authored by two global experts on the management of patients with psychosis, this pocketbook will serve as a useful guide for psychiatrists, trainees, psychiatric specialist nurses, and interested general practitioners. Schizophrenia is one of the most disabling mental illnesses and is also highly prevalent, occurring in approximately 1% of the population and affecting both men and women equally. The disorder has a typical onset of between 15 and 35 years of age and is characterised by impairments in reality, most commonly hallucinations and delusions. It is a highly complex condition and is often confused with other mental disorders such as bipolar disorder. This new edition will cover new DSM-5 diagnostic criteria and to reflect new data and include new longitudinal studies on psychiatric and medical co-morbidity, Genetic and environmental factors, new drug therapies, adherence and the role of depots, new advances in psychosocial therapies (CBT,ACT, & cognitive remediation) and includes an updated and expanded appendix.

The History of the World Federation of Neurology: The First 50 Years

Since its founding in 1957, the World Federation of Neurology (WFN) has been deeply integrated in the development of international collaboration in the field of neurology, and has played a key part in asserting with dissemination of information and the need to learn from each other, independent of political systems, but with a basis in the development of democracy worldwide. This book covers the history of the WFN from its founding in Brussels in 1957 to the present day. Written by a former President and long-standing officer of the WFN, The History of the World Federation of Neurology chronicles the formation and expansion of the WFN, the development of its structure and various committees, and the evolution of its global biennial meeting, the World Congress of Neurology. Sections of the text focus on the key neurologists involved in the development of the WFN, including Houston Merritt, Pearce Bailey Jr, and Ludo van Bogaert, to name but a few, as well as the history of its educational publications, including World Neurology and Journal of the Neurological Sciences.

Oxford Desk Reference: Toxicology (Oxford Desk Reference Series)

Overdose and poisoning are one of the most frequent acute medical presentations seen in emergency departments, and high dependency and intensive care facilities. The Oxford Desk Reference: Toxicology provides an authoritative guide for the management of patients with poisoning. Each chapter includes key clinical features and potential treatment options to help physicians to assess the potential severity of the poisoned patient and provide the optimum clinical care. A reader-friendly layout ensures that information is easy to find and assimilate, and topics are self-contained to aid quick diagnosis. Presented in an easy-to-use double-page spread format, highly bulleted and concise, the Oxford Desk Reference: Toxicology is ideal for quick referral when an acute problem arises. Contributions from the leading figures in toxicology make this book indispensable for all those involved with the management of poisoned patients, especially trainees and consultants working in emergency medicine, acute medicine, and critical care.

Oxford Desk Reference: Toxicology (Oxford Desk Reference Series)

Overdose and poisoning are one of the most frequent acute medical presentations seen in emergency departments, and high dependency and intensive care facilities. The Oxford Desk Reference: Toxicology provides an authoritative guide for the management of patients with poisoning. Each chapter includes key clinical features and potential treatment options to help physicians to assess the potential severity of the poisoned patient and provide the optimum clinical care. A reader-friendly layout ensures that information is easy to find and assimilate, and topics are self-contained to aid quick diagnosis. Presented in an easy-to-use double-page spread format, highly bulleted and concise, the Oxford Desk Reference: Toxicology is ideal for quick referral when an acute problem arises. Contributions from the leading figures in toxicology make this book indispensable for all those involved with the management of poisoned patients, especially trainees and consultants working in emergency medicine, acute medicine, and critical care.

Oxford Textbook of Urological Surgery (Oxford Textbooks in Surgery)

Offering a comprehensive guide, the Oxford Textbook of Urological Surgery is a practical resource mapped to the curriculum for urological training as approved by the General Medical Council (GMC), making it particularly useful in preparation for the Intercollegiate Examination. Presented in a clear and accessible way, this evidence based volume covers all major areas, including functional urology, stone disease, infection, andrology, nephrology, transplantation, uroradiology, and paediatric urology. This highly illustrated full colour textbook has an innovative and user-friendly style, including over 500 photographs, clinical images, and line drawings. Bringing together the expertise of over 100 specialist contributors in the field, the Oxford Textbook of Urological Surgery is a highly valuable source of information, and will become the standard reference text for all who study urological disease and its treatment.

Oxford Textbook of Vascular Surgery (Oxford Textbooks in Surgery)

The Oxford Textbook of Vascular Surgery draws on the expertise of over 130 specialist contributors to encompass the field of vascular surgery. Through the use of figures, findings of contemporary trials, and additional online content, this textbook is an excellent study material for surgical trainees entering their final two years of training, in addition to serving as an effective reference source for practicing surgeons. This volume discusses the epidemiology, vascular biology, clinical features and management of diseases that affect the vasculature and contains dedicated chapters which address topics such as paediatric surgery, damage control surgery, and amputations. The text follows a logical framework which complements the published Intercollegiate Surgery Curriculum making it particularly useful in preparation for the Intercollegiate Examination. The online version of The Oxford Textbook of Vascular Surgery is free for twelve months to individual purchasers of this book and contains the full text of the print edition, links to external sources and informative videos demonstrating current surgical techniques, making this a valuable resource for practicing surgeons. The field of vascular surgery has advanced rapidly in recent years and has expanded to include the techniques of interventional radiology and cardiology which are also extensively covered in this volume, making it an authoritative modern text. By combining contemporary evidence-based knowledge with informative figures, online resources and links to the current training curriculum, The Oxford Textbook of Vascular Surgery is a highly valuable source of information and will become the standard reference text for all who study vascular disease and its treatment.

The Patient's Wish to Die: Research, Ethics, and Palliative Care

Wish to die statements are becoming a frequent phenomenon in terminally ill patients. Those confronted by these statments need to understand the complexity of such wishes, so they can respond competently and compassionately to the requests. If misunderstood, the statements can be taken at face-value and the practitioner may not recognise that a patient is in fact experiencing ambivalent feelings at the end of life, or they may misinterpret the expressed wish to die as a sign of clinical depression. Public debate about the morality and ethics of various end-of-life care options has exploded in recent years. However, it has never been sensitive to the finer aspects of clinical reality or the experiences of patients. The Patient's Wish to Die: Research, Ethics, and Palliative Care brings together that reality and the patient's voice, combining them with different research approaches. It presents the best available knowledge and research methodologies about patients' wishes at the end-of-life, together with a series of ethical views and a discussion about the clinical implications for palliative care. The book presents material in an open and unbiased manner whilst remaining sensitive to the spiritual and existential dimensions of dying, and to the different cultural views that provide meaning to the individual. Written by the best specialists and ethics scholars from around the world, including palliative care practitioners and end-of-life scholars from countries where assisted dying practices are legalized and from those where it isn't, The The Patient's Wish to Die: Research, Ethics, and Palliative Care will prove essential reading for all those working or studying in the field of palliative care.

The Patient's Wish to Die: Research, Ethics, and Palliative Care

Wish to die statements are becoming a frequent phenomenon in terminally ill patients. Those confronted by these statments need to understand the complexity of such wishes, so they can respond competently and compassionately to the requests. If misunderstood, the statements can be taken at face-value and the practitioner may not recognise that a patient is in fact experiencing ambivalent feelings at the end of life, or they may misinterpret the expressed wish to die as a sign of clinical depression. Public debate about the morality and ethics of various end-of-life care options has exploded in recent years. However, it has never been sensitive to the finer aspects of clinical reality or the experiences of patients. The Patient's Wish to Die: Research, Ethics, and Palliative Care brings together that reality and the patient's voice, combining them with different research approaches. It presents the best available knowledge and research methodologies about patients' wishes at the end-of-life, together with a series of ethical views and a discussion about the clinical implications for palliative care. The book presents material in an open and unbiased manner whilst remaining sensitive to the spiritual and existential dimensions of dying, and to the different cultural views that provide meaning to the individual. Written by the best specialists and ethics scholars from around the world, including palliative care practitioners and end-of-life scholars from countries where assisted dying practices are legalized and from those where it isn't, The The Patient's Wish to Die: Research, Ethics, and Palliative Care will prove essential reading for all those working or studying in the field of palliative care.

Health Promotion: Ideology, Discipline, and Specialism

Health Promotion: Ideology, Discipline, and Specialism is a thorough examination of the field, advancing clear proposals for its development and future, and is essential reading for those needing an understanding of the theoretical background, historical context, or the challenges that health promotion faces today. Health promotion is a term which has been used varyingly to describe an ideology, a discipline, or a profession, and has subtly different meanings when used in each of these ways. Dr John Kemm presents a nuanced understanding of the complexities of the field, and careful consideration of the theoretical and practical difficulties involved. With the core belief that health promotion has a vital contribution to make to the health of populations, this book is packed with the knowledge and tools necessary to help people contribute in real and practical ways to health promotion. Its timely examination of the strategies and legislation of successive governments in the UK informs the ongoing debate on heath policy. The importance of health education is explored, including a look at the new possibilities that technological developments will bring. From the wealth of examples and cases studies used to illustrate the ethical principles underlying health promotion, to the examination of the concepts of environmental and lifestyle determinants of health, it is a comprehensive look at health promotion and will be a perfect resource for practitioners and students alike.

Health Promotion: Ideology, Discipline, and Specialism

Health Promotion: Ideology, Discipline, and Specialism is a thorough examination of the field, advancing clear proposals for its development and future, and is essential reading for those needing an understanding of the theoretical background, historical context, or the challenges that health promotion faces today. Health promotion is a term which has been used varyingly to describe an ideology, a discipline, or a profession, and has subtly different meanings when used in each of these ways. Dr John Kemm presents a nuanced understanding of the complexities of the field, and careful consideration of the theoretical and practical difficulties involved. With the core belief that health promotion has a vital contribution to make to the health of populations, this book is packed with the knowledge and tools necessary to help people contribute in real and practical ways to health promotion. Its timely examination of the strategies and legislation of successive governments in the UK informs the ongoing debate on heath policy. The importance of health education is explored, including a look at the new possibilities that technological developments will bring. From the wealth of examples and cases studies used to illustrate the ethical principles underlying health promotion, to the examination of the concepts of environmental and lifestyle determinants of health, it is a comprehensive look at health promotion and will be a perfect resource for practitioners and students alike.

Impact of Addictive Substances and Behaviours on Individual and Societal Well-being (Governance Of Addictive Substances & Behaviours)

Impact of Addictive Substances and Behaviours on Individual and Societal Well-being outlines an innovative and fascinating new framework for understanding the harm that addictive substances and behaviours can cause. Taking a holistic approach and with well-being as a central tenet, it demonstrates how using different methods can lead to a more just and evidence-based approach to dealing with addictions. Presenting the latest and most comprehensive research, the expert team of authors examines the harm caused by addictive substances and behaviour, factors that contribute to addictions, and current European approaches to governing addictive substances and behaviours. It is both legal and illegal drugs, and behaviour that cause harm. For the world as a whole, cigarettes were the second largest cause of ill health and early death in 2010, alcohol the fifth, and illegal drugs the eighteenth. Regular and sustained heavy engagement in addictive substances and behaviour also impacts on quality of life and material living conditions. The well-being framework outlined here for understanding this impact places particular emphasis on the reciprocal relationship between well-being and drug use: well-being can be a driver of the heavy use of addictive substances and behaviours, and also compounds the harm done. Furthermore, the response of society can increase the harm caused by drug use, and stigma, social exclusion, and the actions of the criminal justice system can impair individual and societal well-being considerably. Impact of Addictive Substances and Behaviours on Individual and Societal Well-being is based on the research from ALICE RAP, a multidisciplinary European study of addictive substances and behaviours in contemporary society. A timely addition to the field, this book is essential reading for those wanting to make a real impact in the field of addiction prevention policy, including public managers, practitioners, public health professionals, and stakeholders influencing policy for addictive substances and behaviours, as well as academics.

Impact of Addictive Substances and Behaviours on Individual and Societal Well-being (Governance Of Addictive Substances & Behaviours)

Impact of Addictive Substances and Behaviours on Individual and Societal Well-being outlines an innovative and fascinating new framework for understanding the harm that addictive substances and behaviours can cause. Taking a holistic approach and with well-being as a central tenet, it demonstrates how using different methods can lead to a more just and evidence-based approach to dealing with addictions. Presenting the latest and most comprehensive research, the expert team of authors examines the harm caused by addictive substances and behaviour, factors that contribute to addictions, and current European approaches to governing addictive substances and behaviours. It is both legal and illegal drugs, and behaviour that cause harm. For the world as a whole, cigarettes were the second largest cause of ill health and early death in 2010, alcohol the fifth, and illegal drugs the eighteenth. Regular and sustained heavy engagement in addictive substances and behaviour also impacts on quality of life and material living conditions. The well-being framework outlined here for understanding this impact places particular emphasis on the reciprocal relationship between well-being and drug use: well-being can be a driver of the heavy use of addictive substances and behaviours, and also compounds the harm done. Furthermore, the response of society can increase the harm caused by drug use, and stigma, social exclusion, and the actions of the criminal justice system can impair individual and societal well-being considerably. Impact of Addictive Substances and Behaviours on Individual and Societal Well-being is based on the research from ALICE RAP, a multidisciplinary European study of addictive substances and behaviours in contemporary society. A timely addition to the field, this book is essential reading for those wanting to make a real impact in the field of addiction prevention policy, including public managers, practitioners, public health professionals, and stakeholders influencing policy for addictive substances and behaviours, as well as academics.

Invasive Studies of the Human Epileptic Brain: Principles and Practice

No other neurological condition allows the same opportunities for an intracranial electrophysiological study of the human brain as epilepsy does. Epileptic surgery is designed to remove the epileptic focus from the human brain, thereby effecting either cure or substantial reduction of seizures in an individual with an otherwise intractable condition. Its use as a treatment modality dates from the late 19th century, and it has become a widely used treatment option throughout the world in the last 20-30 years. The complexity of epilepsy cases in surgical centres, and the need for invasive electrode studies for pre-surgical evaluation, are both greatly increasing. Invasive Studies of the Human Epileptic Brain is the definitive reference text on the use of invasive electroencephalographic (EEG) diagnostic studies in human epilepsy. Written by some of the most renowned epilepsy experts of the 20th and 21st centuries, the authors provide their expertise and insights into the identification and mapping of intracranial epileptiform and non-epileptiform activity, mapping of the human brain function, and approaches in the use of invasive electroencephalography in a variety of clinical situations. The book is organized into an easily readable series of chapters and is brilliantly illustrated with case studies; each providing an intuitively comprehensive approach to invasive brain studies.