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Cognitive Neuroscience of Aging: Linking Cognitive and Cerebral Aging

by Roberto Cabeza, Lars Nyberg and Denise C. Park

This second edition of the popular Cognitive Neuroscience of Aging provides up-to-date coverage of the most fundamental topics in this discipline. Like the first edition, this volume accessibly and comprehensively reviews the neural mechanisms of cognitive aging appropriate to both professionals and students in a variety of domains, including psychology, neuroscience, neuropsychology, neurology, and psychiatry. The chapters are organized into three sections. The first section focuses on major questions regarding methodological approaches and experimental design. It includes chapters on structural imaging (MRI, DTI), functional imaging (fMRI), and molecular imaging (dopamine PET, etc), and covers multimodal imaging, longitudinal studies, and the interpretation of imaging findings. The second section concentrates on specific cognitive abilities, including attention and inhibitory control, executive functions, memory, and emotion. The third section turns to domains with health and clinical implications, such as the emergence of cognitive deficits in middle age, the role of genetics, the effects of modulatory variables (hypertension, exercise, cognitive engagement), and the distinction between healthy aging and the effects of dementia and depression. Taken together, the chapters in this volume, written by many of the most eminent scientists as well as young stars in this discipline, provide a unified and comprehensive overview of cognitive neuroscience of aging.

Design and Analysis of Time Series Experiments

by Richard McCleary David McDowall Bradley Bartos

Design and Analysis of Time Series Experiments presents the elements of statistical time series analysis while also addressing recent developments in research design and causal modeling. A distinguishing feature of the book is its integration of design and analysis of time series experiments. Readers learn not only how-to skills but also the underlying rationales for design features and analytical methods. ARIMA algebra, Box-Jenkins-Tiao models and model-building strategies, forecasting, and Box-Tiao impact models are developed in separate chapters. The presentation of the models and model-building assumes only exposure to an introductory statistics course, with more difficult mathematical material relegated to appendices. Separate chapters cover threats to statistical conclusion validity, internal validity, construct validity, and external validity with an emphasis on how these threats arise in time series experiments. Design structures for controlling the threats are presented and illustrated through examples. The chapters on statistical conclusion validity and internal validity introduce Bayesian methods, counterfactual causality, and synthetic control group designs. Building on the earlier time series books by McCleary and McDowall, Design and Analysis of Time Series Experiments includes recent developments in modeling, and considers design issues in greater detail than does any existing work. Drawing examples from criminology, economics, education, pharmacology, public policy, program evaluation, public health, and psychology, the text is addressed to researchers and graduate students in a wide range of behavioral, biomedical and social sciences. It will appeal to those who want to conduct or interpret time series experiments, as well as to those interested in research designs for causal inference.

DESIGN & ANALYSIS TIME SERIES EXPERIM C

by David McDowall Richard McCleary Bradley Bartos

Design and Analysis of Time Series Experiments presents the elements of statistical time series analysis while also addressing recent developments in research design and causal modeling. A distinguishing feature of the book is its integration of design and analysis of time series experiments. Readers learn not only how-to skills but also the underlying rationales for design features and analytical methods. ARIMA algebra, Box-Jenkins-Tiao models and model-building strategies, forecasting, and Box-Tiao impact models are developed in separate chapters. The presentation of the models and model-building assumes only exposure to an introductory statistics course, with more difficult mathematical material relegated to appendices. Separate chapters cover threats to statistical conclusion validity, internal validity, construct validity, and external validity with an emphasis on how these threats arise in time series experiments. Design structures for controlling the threats are presented and illustrated through examples. The chapters on statistical conclusion validity and internal validity introduce Bayesian methods, counterfactual causality, and synthetic control group designs. Building on the earlier time series books by McCleary and McDowall, Design and Analysis of Time Series Experiments includes recent developments in modeling, and considers design issues in greater detail than does any existing work. Drawing examples from criminology, economics, education, pharmacology, public policy, program evaluation, public health, and psychology, the text is addressed to researchers and graduate students in a wide range of behavioral, biomedical and social sciences. It will appeal to those who want to conduct or interpret time series experiments, as well as to those interested in research designs for causal inference.

Immigration, Cultural Identity, and Mental Health: Psycho-social Implications of the Reshaping of America

by Eugenio M. Rothe Andres J. Pumariega

What will the ethnic, racial and cultural face of the United States look like in the upcoming decades, and how will the American population adapt to these changes? Immigration, Cultural Identity, and Mental Health: Psycho-social Implications of the Reshaping of America outlines the various psychosocial impacts of immigration on cultural identity and its impact on mainstream culture. Thoroughly researched, this book examines how cultural identity relates to individual mental health and should be taken into account in mental health treatment. In a time when globalization is decreasing the importance of national boundaries and impacting cultural identity for both minority and mainstream populations, the authors explore the multiple facets of what immigration means for culture and mental health. The authors review the concept of acculturation and examine not only how the immigrant's identity transforms through this process, but also how the immigrant transforms the host culture through inter-culturation. The authors detail the risk factors and protective factors that affect the first generation and subsequent generations of immigrants in their adaptation to American society, and also seek to dispel myths and clarify statistics of criminality among immigrant populations. Further, the book aims to elucidate the importance of ethnicity and race in the psycho-therapeutic encounter and offers treatment recommendations on how to approach and discuss issues of ethnicity and race in psychotherapy. It also presents evidence-based psychological treatment interventions for immigrants and members of minority populations and shows how psychotherapy involves the creation of new, more adaptive narratives that can provide healing, personal growth, and relevance to the immigrant experience. Throughout, the authors provide clinical case examples to illustrate the concepts presented.

Immigration, Cultural Identity, and Mental Health: Psycho-social Implications of the Reshaping of America

by Eugenio M. Rothe Andres J. Pumariega

What will the ethnic, racial and cultural face of the United States look like in the upcoming decades, and how will the American population adapt to these changes? Immigration, Cultural Identity, and Mental Health: Psycho-social Implications of the Reshaping of America outlines the various psychosocial impacts of immigration on cultural identity and its impact on mainstream culture. Thoroughly researched, this book examines how cultural identity relates to individual mental health and should be taken into account in mental health treatment. In a time when globalization is decreasing the importance of national boundaries and impacting cultural identity for both minority and mainstream populations, the authors explore the multiple facets of what immigration means for culture and mental health. The authors review the concept of acculturation and examine not only how the immigrant's identity transforms through this process, but also how the immigrant transforms the host culture through inter-culturation. The authors detail the risk factors and protective factors that affect the first generation and subsequent generations of immigrants in their adaptation to American society, and also seek to dispel myths and clarify statistics of criminality among immigrant populations. Further, the book aims to elucidate the importance of ethnicity and race in the psycho-therapeutic encounter and offers treatment recommendations on how to approach and discuss issues of ethnicity and race in psychotherapy. It also presents evidence-based psychological treatment interventions for immigrants and members of minority populations and shows how psychotherapy involves the creation of new, more adaptive narratives that can provide healing, personal growth, and relevance to the immigrant experience. Throughout, the authors provide clinical case examples to illustrate the concepts presented.

Palliative Psychology: Clinical Perspectives on an Emerging Specialty

by E. Alessandra Strada

Palliative Psychology provides clinical, evidence-based training in palliative and end of life care for clinical psychologists to accomplish specific therapeutic goals. Chapters provide a clear road map for approaching assessment and treatment by reviewing the use of psychotropic medications for patients with advanced and terminal illness, basic but important aspects of pain medication, in depth psychological and psychiatric assessment for patients with advanced illness and their caregivers, and assessment tools, highlighting the specific clinical contexts for their use. The volume also includes evidence-based psychotherapy models that have been shown effective in treating various manifestations of psychological distress in patients and caregivers. In addition to clinical topics, Palliative Psychology addresses crucial and often sensitive professional issues, including communication and collaboration with medical providers and issues of stress and burnout. Psychologists will learn how to best communicate the results of their assessments and treatment plan goals to other care providers in order to foster collaboration and better position themselves as advocates for their patients. Insight-oriented and practical suggestions will help clinicians manage the emotional intensity of this work and channel the therapeutic potential of their emotional reactions into their work with patients and caregivers.

Palliative Psychology: Clinical Perspectives on an Emerging Specialty

by E. Alessandra Strada

Palliative Psychology provides clinical, evidence-based training in palliative and end of life care for clinical psychologists to accomplish specific therapeutic goals. Chapters provide a clear road map for approaching assessment and treatment by reviewing the use of psychotropic medications for patients with advanced and terminal illness, basic but important aspects of pain medication, in depth psychological and psychiatric assessment for patients with advanced illness and their caregivers, and assessment tools, highlighting the specific clinical contexts for their use. The volume also includes evidence-based psychotherapy models that have been shown effective in treating various manifestations of psychological distress in patients and caregivers. In addition to clinical topics, Palliative Psychology addresses crucial and often sensitive professional issues, including communication and collaboration with medical providers and issues of stress and burnout. Psychologists will learn how to best communicate the results of their assessments and treatment plan goals to other care providers in order to foster collaboration and better position themselves as advocates for their patients. Insight-oriented and practical suggestions will help clinicians manage the emotional intensity of this work and channel the therapeutic potential of their emotional reactions into their work with patients and caregivers.

Healthier: Fifty Thoughts on the Foundations of Population Health

by Sandro Galea

Fifty essays on the state of population health from a vanguard voice in the field Public health can rightly claim its share of victories: healthier cities, widespread sanitation, broader availability of nutrient-rich food, and reductions in violence and injury. But for all these gains, today we face a new set of challenges, ones complicated by political and professional shifts that threaten to fundamentally change the health of populations. Healthier is both an affirmation and an essential summary of the current challenges and opportunities for those working in and around the improvement of population health. The essays contained here champion an approach to health that is consequentialist and rooted in social justice -- an expansion of traditional, quantitatively motivated public health that will both inform and inspire any reader from student to seasoned practitioner. Galea's cogent, incisive arguments guarantee that his perspective, currently at the forefront of public health, will soon become conventional wisdom.

Healthier: Fifty Thoughts on the Foundations of Population Health

by Sandro Galea

Fifty essays on the state of population health from a vanguard voice in the field Public health can rightly claim its share of victories: healthier cities, widespread sanitation, broader availability of nutrient-rich food, and reductions in violence and injury. But for all these gains, today we face a new set of challenges, ones complicated by political and professional shifts that threaten to fundamentally change the health of populations. Healthier is both an affirmation and an essential summary of the current challenges and opportunities for those working in and around the improvement of population health. The essays contained here champion an approach to health that is consequentialist and rooted in social justice -- an expansion of traditional, quantitatively motivated public health that will both inform and inspire any reader from student to seasoned practitioner. Galea's cogent, incisive arguments guarantee that his perspective, currently at the forefront of public health, will soon become conventional wisdom.

The Guide to Interpersonal Psychotherapy: Updated and Expanded Edition

by Myrna M. Weissman John C. Markowitz Gerald L. Klerman

The Guide to Interpersonal Psychotherapy is the definitive, practical guide to Interpersonal Psychotherapy (IPT) for clinicians and researchers. IPT is a well-researched, time-limited, and diagnosis-focused therapy. An update and expansion of the original 1984, 2000, and 2007 IPT manuals, this guide illustrates not only individual IPT treatment for patients with major depression but also adaptations of IPT for different diagnoses, patient populations, and treatment formats. This book is the basis for the extensive research that has validated IPT and led to its listing in treatment guidelines. Written by the originators of the treatment and one of its leading researchers, this updated and expanded guide describes how to approach clinical encounters with patients, how to focus IPT treatment, and how to handle therapeutic difficulties. IPT can be combined with medication, and it is a safe alternative to medication for individuals who may not be able to take antidepressants. IPT has been shown not only to relieve symptoms but to build social skills as well. Learn how to use IPT to effectively treat depression and other disorders including bipolar disorder, anxiety disorders, eating disorders, posttraumatic stress, and borderline personality disorder. With clinical examples and sample therapist scripts throughout, The Guide summarizes the theoretical and empirical background of IPT and focuses on teaching you the best way to deliver this effective, immensely practical treatment.

Children and Environmental Toxins: What Everyone Needs to Know® (What Everyone Needs To Know®)

by Philip J. Landrigan Mary M. Landrigan

More than 80,000 new chemicals have been developed and released into the global environment during the last four decades. Today the World Health Organization attributes more than one-third of all childhood deaths to environmental causes, and as rates of childhood disease skyrocket -- autism, asthma, ADHD, obesity, diabetes, and even birth defects -- it raises serious, difficult questions around how the chemical environment is impacting children's health. Children and Environmental Toxins: What Everyone Needs to Know® offers an accessible guide to understanding and identifying the potential sources of harm in a child's environment. Written by experts in pediatrics and environmental health and formatted in an easy to follow question-and-answer format, it offers parents, care providers, and activists a reliable introduction to a hotly debated topic. As the burdens of environmental toxins and disease continue to defy borders, this book provides a new benchmark to understanding the potential threats in our environment and food. No parent or care provider should be without it.

CHILDREN & ENVIRONMENTAL TOXINS WENK C: What Everyone Needs to Know® (What Everyone Needs To Know®)

by Philip J. Landrigan Mary M. Landrigan

More than 80,000 new chemicals have been developed and released into the global environment during the last four decades. Today the World Health Organization attributes more than one-third of all childhood deaths to environmental causes, and as rates of childhood disease skyrocket -- autism, asthma, ADHD, obesity, diabetes, and even birth defects -- it raises serious, difficult questions around how the chemical environment is impacting children's health. Children and Environmental Toxins: What Everyone Needs to Know® offers an accessible guide to understanding and identifying the potential sources of harm in a child's environment. Written by experts in pediatrics and environmental health and formatted in an easy to follow question-and-answer format, it offers parents, care providers, and activists a reliable introduction to a hotly debated topic. As the burdens of environmental toxins and disease continue to defy borders, this book provides a new benchmark to understanding the potential threats in our environment and food. No parent or care provider should be without it.

Occupational and Environmental Health


Praise for Previous Editions: "This splendid book [...]is authoritative, well written, and ably edited." - Occupational & Environmental Medicine "The book provides a logical, structured exposition of a diverse multidisciplinary speciality, employing a language and format designed to educate the novice student and seasoned practitioner alike - a vital contribution to the field." - New England Journal of Medicine Occupational and environmental contributions to the occurrence of disease and injury represent a core component of public health and health care. Factors in the workplace and the ambient environment have significant impacts on individual and community health. Occupational and Environmental Health is a comprehensive, practical textbook for understanding how work and environment influence individual and population health. Comprising 40 chapters written by national and international experts, this book combines theory and practical insights to help readers effectively recognize and prevent occupational and environmental disease and injury.

Occupational and Environmental Health

by Barry S. Levy, David H. Wegman, Sherry L. Baron, Rosemary K. Sokas and Heather L. McStowe

Praise for Previous Editions: "This splendid book [...]is authoritative, well written, and ably edited." - Occupational & Environmental Medicine "The book provides a logical, structured exposition of a diverse multidisciplinary speciality, employing a language and format designed to educate the novice student and seasoned practitioner alike - a vital contribution to the field." - New England Journal of Medicine Occupational and environmental contributions to the occurrence of disease and injury represent a core component of public health and health care. Factors in the workplace and the ambient environment have significant impacts on individual and community health. Occupational and Environmental Health is a comprehensive, practical textbook for understanding how work and environment influence individual and population health. Comprising 40 chapters written by national and international experts, this book combines theory and practical insights to help readers effectively recognize and prevent occupational and environmental disease and injury.

The Oxford Handbook of Eating Disorders (Oxford Library of Psychology)

by W. Stewart Agras and Athena Robinson

The Oxford Handbook of Eating Disorders provides current insights from established experts into the phenomenology, epidemiology, prevention, and treatment of eating disorders. Fully revised to reflect new DSM-5 classification and diagnostic criteria, each chapter of the Second Edition has been updated to feature the latest clinical research findings, applications, and approaches to understanding eating disorders. An additional chapter on emerging issues explores critical questions pertaining to ethics and the use of technology in treating eating disorders. With information on newly documented syndromes and a new section on bariatric surgery, this handbook not only encapsulates where the field is at but also offers astute perspectives on how the field is changing. Including both practical specifics, like literature reviews and clinical applications, as well as a broad view of foundational topics, this handbook is essential for scientists, clinicians, experts, and students alike.

Pressure Cooker: Why Home Cooking Won't Solve Our Problems and What We Can Do About It

by Sarah Bowen Joslyn Brenton Sinikka Elliott

Food is at the center of national debates about how Americans live and the future of the planet. Not everyone agrees about how to reform our relationship to food, but one suggestion rises above the din: We need to get back in the kitchen. Amid concerns about rising rates of obesity and diabetes, unpronounceable ingredients, and the environmental footprint of industrial agriculture, food reformers implore parents to slow down, cook from scratch, and gather around the dinner table. Making food a priority, they argue, will lead to happier and healthier families. But is it really that simple? In this riveting and beautifully-written book, Sarah Bowen, Joslyn Brenton, and Sinikka Elliott take us into the kitchens of nine women to tell the complicated story of what it takes to feed a family today. All of these mothers love their children and want them to eat well. But their kitchens are not equal. From cockroach infestations and stretched budgets to picky eaters and conflicting nutrition advice, Pressure Cooker exposes how modern families struggle to confront high expectations and deep-seated inequalities around getting food on the table. Based on extensive interviews and field research in the homes and kitchens of a diverse group of American families, Pressure Cooker challenges the logic of the most popular foodie mantras of our time, showing how they miss the mark and up the ante for parents and children. Romantic images of family meals are inviting, but they create a fiction that does little to fix the problems with the food system. The unforgettable stories in this book evocatively illustrate how class inequality, racism, sexism, and xenophobia converge at the dinner table. If we want a food system that is fair, equitable, and nourishing, we must look outside the kitchen for answers.

Pressure Cooker: Why Home Cooking Won't Solve Our Problems and What We Can Do About It

by Sarah Bowen Sinikka Elliott Joslyn Brenton

Food is at the center of national debates about how Americans live and the future of the planet. Not everyone agrees about how to reform our relationship to food, but one suggestion rises above the din: We need to get back in the kitchen. Amid concerns about rising rates of obesity and diabetes, unpronounceable ingredients, and the environmental footprint of industrial agriculture, food reformers implore parents to slow down, cook from scratch, and gather around the dinner table. Making food a priority, they argue, will lead to happier and healthier families. But is it really that simple? In this riveting and beautifully-written book, Sarah Bowen, Joslyn Brenton, and Sinikka Elliott take us into the kitchens of nine women to tell the complicated story of what it takes to feed a family today. All of these mothers love their children and want them to eat well. But their kitchens are not equal. From cockroach infestations and stretched budgets to picky eaters and conflicting nutrition advice, Pressure Cooker exposes how modern families struggle to confront high expectations and deep-seated inequalities around getting food on the table. Based on extensive interviews and field research in the homes and kitchens of a diverse group of American families, Pressure Cooker challenges the logic of the most popular foodie mantras of our time, showing how they miss the mark and up the ante for parents and children. Romantic images of family meals are inviting, but they create a fiction that does little to fix the problems with the food system. The unforgettable stories in this book evocatively illustrate how class inequality, racism, sexism, and xenophobia converge at the dinner table. If we want a food system that is fair, equitable, and nourishing, we must look outside the kitchen for answers.

Antibiotics: What Everyone Needs to Know® (What Everyone Needs To Know®)

by Mary E. Wilson

Virtually everyone has taken antibiotics. They can be lifesavers -- and they can be useless. What are they? How are they used? And what happens as the effectiveness of antibiotics continues to decline? Antibiotics: What Everyone Needs to Know® examines the personal and societal implications of our planet's most important -- and frequently misused -- medications. In a question-and-answer format, it unpacks the most complicated aspects of this issue, including: How antibiotics are used (and overused) in humans, plants, and livestock; the causes and consequences of bacterial resistance to antibiotics; how the globalized world enables antibiotic resistance to spread quickly; and the difficult decisions ahead for both medical care and the food system. Grounded in the latest scientific research and crafted for general readers, Antibiotics: What Everyone Needs to Know® offers a clear-eyed overview of where we are, and what the future holds, as antibiotics lose their power.

ANTIBIOTICS WENK C: What Everyone Needs to Know® (What Everyone Needs To Know®)

by Mary E. Wilson

Virtually everyone has taken antibiotics. They can be lifesavers -- and they can be useless. What are they? How are they used? And what happens as the effectiveness of antibiotics continues to decline? Antibiotics: What Everyone Needs to Know® examines the personal and societal implications of our planet's most important -- and frequently misused -- medications. In a question-and-answer format, it unpacks the most complicated aspects of this issue, including: How antibiotics are used (and overused) in humans, plants, and livestock; the causes and consequences of bacterial resistance to antibiotics; how the globalized world enables antibiotic resistance to spread quickly; and the difficult decisions ahead for both medical care and the food system. Grounded in the latest scientific research and crafted for general readers, Antibiotics: What Everyone Needs to Know® offers a clear-eyed overview of where we are, and what the future holds, as antibiotics lose their power.

Clinical Pocket Guide to Advanced Practice Palliative Nursing

by Constance Dahlin, Patrick J. Coyne, Betty R. Ferrell

The Clinical Pocket Guide to Advanced Practice Palliative Nursing is a companion guide to Advanced Practice Palliative Nursing, the first text devoted to advanced practice nursing care of the seriously ill and dying. Each chapter of this pocket guide presents point-of-care guidance on palliative care issues for quick reference in daily practice. Edited by leaders in the field, this handbook provides consistency in the nursing process from assessment to management and evaluation of symptoms and various clinical situations. The Clinical Pocket Guide to Advanced Practice Palliative Nursing contains clinical pearls developed from the textbook and practical tools on pain and symptom assessment, functional status, and communication, making it an ideal resource for practicing APNs. management and evaluation of symptoms and various clinical situations.

The Gerontological Imagination: An Integrative Paradigm of Aging

by Kenneth F. Ferraro

The scientific study of aging is a relatively nascent field of inquiry. Although philosophic and literary reflections on what it means to grow older appear in the earliest historical records, the systematic study of aging began in earnest about a century ago. Scholarly interest in the topic has accelerated in recent decades, due in part to rapid population aging in developed nations. As a result, the study of aging has been incorporated into many disciplines, emphasizing concepts, theories, and methods to elucidate the antecedents and consequences of growing older. Although each discipline has key concepts and empirical generalizations about aging, there is little agreement across disciplines about the intellectual core of gerontology. Each discipline brings its own intellectual heritage and perspective to the study of aging, but the question posed by author Ken Ferraro is whether there is an emergent perspective or way of thinking about aging that transcends the disciplines. Biologists, psychologists, and sociologists may claim an interest in gerontology, but do they have a common image of aging or a set of principles to guide their research? Do they share a paradigm-a fundamental image of aging-that incorporates concepts and empirical generalizations from multiple disciplines? And when disciplinary approaches to gerontology clash, which approach or conceptualization of aging is likely to emerge as part of the paradigm? Although biologists, psychologists, and social scientists share an interest in the study of aging, they are distinctive in how they conduct their research. The Gerontological Imagination provides an integrative paradigm of aging that makes it the first book to identify intellectual common ground among scholars studying aging. Ferraro identifies an underlying set of principles that constitute a paradigm for the study of aging: causality, life course analysis, multifaceted change, heterogeneity, accumulation processes, and ageism. The proposed paradigm provides an efficient way to identify and interpret essential ideas, findings, models, and theories across multiple disciplines that study aging.

The Gerontological Imagination: An Integrative Paradigm of Aging

by Kenneth F. Ferraro

The scientific study of aging is a relatively nascent field of inquiry. Although philosophic and literary reflections on what it means to grow older appear in the earliest historical records, the systematic study of aging began in earnest about a century ago. Scholarly interest in the topic has accelerated in recent decades, due in part to rapid population aging in developed nations. As a result, the study of aging has been incorporated into many disciplines, emphasizing concepts, theories, and methods to elucidate the antecedents and consequences of growing older. Although each discipline has key concepts and empirical generalizations about aging, there is little agreement across disciplines about the intellectual core of gerontology. Each discipline brings its own intellectual heritage and perspective to the study of aging, but the question posed by author Ken Ferraro is whether there is an emergent perspective or way of thinking about aging that transcends the disciplines. Biologists, psychologists, and sociologists may claim an interest in gerontology, but do they have a common image of aging or a set of principles to guide their research? Do they share a paradigm-a fundamental image of aging-that incorporates concepts and empirical generalizations from multiple disciplines? And when disciplinary approaches to gerontology clash, which approach or conceptualization of aging is likely to emerge as part of the paradigm? Although biologists, psychologists, and social scientists share an interest in the study of aging, they are distinctive in how they conduct their research. The Gerontological Imagination provides an integrative paradigm of aging that makes it the first book to identify intellectual common ground among scholars studying aging. Ferraro identifies an underlying set of principles that constitute a paradigm for the study of aging: causality, life course analysis, multifaceted change, heterogeneity, accumulation processes, and ageism. The proposed paradigm provides an efficient way to identify and interpret essential ideas, findings, models, and theories across multiple disciplines that study aging.

Error and Uncertainty in Diagnostic Radiology

by Michael A. Bruno

Over the past decade, radiological imaging tests - including CT scanning, MRI, PET, X-rays, ultrasound, fluoroscopy and other modalities - have become essential to the routine diagnostic process. While these modern advanced medical images and their striking anatomic detail have discovered underlying issues, they have also contributed to a false impression of infallibility. Unlike other straightforward diagnostic tests, such as the EKG or blood chemistry panel, radiological imaging tests are highly variable and complex, often yielding uncertain results, as well as frequent false-negatives and false-positives. The experts who interpret the images (the diagnostic radiologists) sometimes make mistakes: the practice of diagnostic radiology is a fallible, human endeavour, one involving complex perceptual, neuro-physiological and cognitive processes employed under a wide range of circumstances, and with a great deal of variability. Error and Uncertainty in Diagnostic Radiology opens the 'black box,' of medical imaging, exposing the remarkable inner workings of the process of diagnostic radiology-including how and why it can sometimes go tragically wrong. The occurrence of radiological error is shown to be fundamentally intertwined with the underlying high level of uncertainty known to be present in the diagnostic process. As a foremost expert on radiology quality and safety, Dr. Bruno provides insight into the various types of radiologist error, along with a conceptual framework for understanding error and uncertainty in radiology, leading to practical strategies for error prevention and for reducing the risk of harm to patients when errors inevitably occur. This book is essential for radiologists, members of the Society to Improve Diagnosis in Medicine, emergency physicians, medical educators, medical and hospice administrators, especially quality and safety officers, as well as malpractice insurance carriers.

Error and Uncertainty in Diagnostic Radiology

by Michael A. Bruno

Over the past decade, radiological imaging tests - including CT scanning, MRI, PET, X-rays, ultrasound, fluoroscopy and other modalities - have become essential to the routine diagnostic process. While these modern advanced medical images and their striking anatomic detail have discovered underlying issues, they have also contributed to a false impression of infallibility. Unlike other straightforward diagnostic tests, such as the EKG or blood chemistry panel, radiological imaging tests are highly variable and complex, often yielding uncertain results, as well as frequent false-negatives and false-positives. The experts who interpret the images (the diagnostic radiologists) sometimes make mistakes: the practice of diagnostic radiology is a fallible, human endeavour, one involving complex perceptual, neuro-physiological and cognitive processes employed under a wide range of circumstances, and with a great deal of variability. Error and Uncertainty in Diagnostic Radiology opens the 'black box,' of medical imaging, exposing the remarkable inner workings of the process of diagnostic radiology-including how and why it can sometimes go tragically wrong. The occurrence of radiological error is shown to be fundamentally intertwined with the underlying high level of uncertainty known to be present in the diagnostic process. As a foremost expert on radiology quality and safety, Dr. Bruno provides insight into the various types of radiologist error, along with a conceptual framework for understanding error and uncertainty in radiology, leading to practical strategies for error prevention and for reducing the risk of harm to patients when errors inevitably occur. This book is essential for radiologists, members of the Society to Improve Diagnosis in Medicine, emergency physicians, medical educators, medical and hospice administrators, especially quality and safety officers, as well as malpractice insurance carriers.

Epidemiology by Design: A Causal Approach to the Health Sciences

by Daniel Westreich

A (LONG OVERDUE) CAUSAL APPROACH TO INTRODUCTORY EPIDEMIOLOGY Epidemiology is recognized as the science of public health, evidence-based medicine, and comparative effectiveness research. Causal inference is the theoretical foundation underlying all of the above. No introduction to epidemiology is complete without extensive discussion of causal inference; what's missing is a textbook that takes such an approach. Epidemiology by Design takes a causal approach to the foundations of traditional introductory epidemiology. Through an organizing principle of study designs, it teaches epidemiology through modern causal inference approaches, including potential outcomes, counterfactuals, and causal identification conditions. Coverage in this textbook includes: · Introduction to measures of prevalence and incidence (survival curves, risks, rates, odds) and measures of contrast (differences, ratios); the fundamentals of causal inference; and principles of diagnostic testing, screening, and surveillance · Description of three key study designs through the lens of causal inference: randomized trials, prospective observational cohort studies, and case-control studies · Discussion of internal validity (within a sample), external validity, and population impact: the foundations of an epidemiologic approach to implementation science For first-year graduate students and advanced undergraduates in epidemiology and public health fields more broadly, Epidemiology by Design offers a rigorous foundation in epidemiologic methods and an introduction to methods and thinking in causal inference. This new textbook will serve as a foundation not just for further study of the field, but as a head start on where the field is going.

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