Genes and Mechanisms in Vertebrate Sex Determination (2001) (Experientia Supplementum #91)
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- Synopsis
- Following an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions.
- Copyright:
- 2001
Book Details
- Book Quality:
- Publisher Quality
- ISBN-13:
- 9783034877817
- Related ISBNs:
- 9783764361686
- Publisher:
- Birkhäuser Basel
- Date of Addition:
- 08/14/22
- Copyrighted By:
- Springer Basel AG
- Adult content:
- No
- Language:
- English
- Has Image Descriptions:
- No
- Categories:
- Nonfiction, Science, Animals
- Submitted By:
- Bookshare Staff
- Usage Restrictions:
- This is a copyrighted book.
- Edited by:
- Gerd Scherer
- Edited by:
- Michael Schmid