Chemokine Biology - Basic Research and Clinical Application: Vol. 1: Immunobiology of Chemokines (2006) (Progress in Inflammation Research)

By: William W. Agace and Marco Baggiolini and Craig T. Morita and Federica Sallusto and José Miguel Rodriguez-Frade and Paul Kubes and Basil O. Gerber and Joost J. Oppenheim and Sergio Romagnani and Grant McFadden and Osamu Yoshie

Sign Up Now! Already a Member? Log In
You must be logged into UK education collection to access this title. Learn about membership options, or view our freely available titles.

Synopsis: Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They selectively attract leukocytes to inflammatory foci, inducing both cell migration and activation. They are involved in various diseases, like atherosclerosis, lung and skin inflammation, multiple sclerosis, or HIV.Volume 1 of this two-volume set discusses the immunobiology of chemokines. It is divided into two parts: a) cellular targets in innate and adaptive immunity, and b) effector cell traffic-unrelated functions. Together with volume 2, which discusses the pathophysiology of chemokines, both volumes give a comprehensive overview of chemokine biology.