Diuretics (1995) (Handbook of Experimental Pharmacology #117)

By: O. S. Better and A. Busch and J. Dorup and H. Endou and R. Greger and W. G. Guder and M. Hosoyamanda and M. Hropot and B. Kaissling and T. R. Kleymann and H. Knauf and F. Lang and H. J. Lang and W. Möhrke and E. Mutschler and T. Netzer and L. G. Palmer and J. B. Puschett and I. Rubinstein and M. Schmolke and F. Ullrich and K. J. Ullrich and H. Velazquez and J. Winaver

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Synopsis: The action of diuretics including cellular mechanisms of action, pharmacokinetics, and clinical usage, with much emphasis placed on the most recent findings on the pharmacodynamics of the respective drugs. During the past twenty-five years since volume 14 on Diuretica was published in the Handbook series, the cellular mechanisms of action of diuretics have slowly been unravelled. Today, the role of action within the target cells is known for most of the substances discussed. This has provided a new basis not only for the understanding of drug action but also for secondary effects and interactions. The book represents a comprehensive reference work on the diverse groups of diuretics which are among the most frequently prescribed medications.