Annual Reports in Combinatorial Chemistry and Molecular Diversity (1997) (Annual Reports in Combinatorial Chemistry & Molecular Diversity #1)

Synopsis

Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed, more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. This first volume covers: (i) combinatorial chemistry, (ii) combinatorial biology and evolution, and (iii) informatics and related topics. Within each section chapters are prepared by experts in the field, including, for example, in Section I: Coverage of mixture pools vs. parallel individual compound synthesis, solution vs. solid-phase synthesis, analytical tools, and automation. Section II highlights selection strategies and library-based evolution, phage display, peptide and nucleic acid libraries. Section III covers databases and library design, high through-put screening, coding strategies vs. deconvolutions, intellectual property issues, deals and collaborations, and successes to date.

Copyright:

1997

Book Details

Book Quality:

Publisher Quality

ISBN-13:

9780306469046

Related ISBNs:

9789072199232

Publisher:

Springer Netherlands

Date of Addition:

12/12/20

Copyrighted By:

Springer Science+Business Media Dordrecht 1997

Adult content:

No

Language:

English

Has Image Descriptions:

No

Categories:

Nonfiction, Science, Technology, Medicine

Submitted By:

Bookshare Staff

Usage Restrictions:

This is a copyrighted book.

Edited by:

W.H. Moos

Edited by:

M.R. Pavia

Edited by:

B.K. Kay

Edited by:

Andrew D. Ellington